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Hepatitis E Virus and Chronic Hepatitis in Organ-Transplant Recipients
Open accessAbstract
Hepatitis E virus (HEV) is considered an agent responsible for acute hepatitis that does not progress to chronic hepatitis. We identified 14 cases of acute HEV infection in three patients receiving liver transplants, nine receiving kidney transplants, and two receiving kidney and pancreas transplants. All patients were positive for serum HEV RNA. Chronic hepatitis developed in eight patients, as confirmed by persistently elevated aminotransferase levels, serum HEV RNA, and histologic features of chronic hepatitis. The time from transplantation to diagnosis was significantly shorter and the total counts of lymphocytes and of CD2, CD3, and CD4 T cells were significantly lower in patients in whom chronic disease developed.
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Citations
Cited by
Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis
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Kamar, N., Dalton, H. R., Abravanel, F., & Izopet, J. (2014) · Clinical Microbiology Reviews · doi:10.1128/cmr.00057-13 · Cited by 675
Self-citationEASL Clinical Practice Guidelines on hepatitis E virus infection
Dalton, H. R., Kamar, N., Baylis, S. A., Moradpour, D., Wedemeyer, H., & Negro, F. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.03.005 · Cited by 665
Self-citationHepatitis-E-Virus: Stellungnahmen des Arbeitskreises Blut des Bundesministeriums für Gesundheit
Gesundheit, M. D. A. B. D. B. F. (2015) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-014-2103-4 · Cited by 374
Zoonotic hepatitis E: animal reservoirs and emerging risks
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Metadata
- Authors
- Kamar, N., Selves, J., Mansuy, J.-M., Ouezzani, L., Péron, J.-M., Guitard, J., Cointault, O., Esposito, L., Abravanel, F., Danjoux, M., Durand, D., Vinel, J.-P., Izopet, J., & Rostaing, L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2008-02-21
- Volume
- 358
- Issue
- 8
- Pages
- 811-817
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2012382212
- Cited by
- 1,350
- References
- 0
- FWCI
- 48.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Hepatitis E Virus and Chronic Hepatitis in Organ-Transplant Recipients. https://app.cochat.ai/papers/10.1056/nejmoa0706992
- The paper
- Kamar, N., Selves, J., Mansuy, J.-M., Ouezzani, L., Péron, J.-M., Guitard, J., Cointault, O., Esposito, L., Abravanel, F., Danjoux, M., Durand, D., Vinel, J.-P., Izopet, J., & Rostaing, L. (2008). Hepatitis E Virus and Chronic Hepatitis in Organ-Transplant Recipients. New England Journal of Medicine. https://doi.org/10.1056/nejmoa0706992
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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