The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
The prognosis of acute and persistent low-back pain: a meta-analysis
Open accessAbstract
BACKGROUND: Although low-back pain is a highly prevalent condition, its clinical course remains uncertain. Our main objective was to systematically review the literature on the clinical course of pain and disability in patients with acute and persistent low-back pain. Our secondary objective was to investigate whether pain and disability have similar courses. METHODS: We performed a meta-analysis of inception cohort studies. We identified eligible studies by searching MEDLINE, Embase and CINAHL. We included prospective studies that enrolled an episode-inception cohort of patients with acute or persistent low-back pain and that measured pain, disability or recovery. Two independent reviewers extracted data and assessed methodologic quality. We used mixed models to determine pooled estimates of pain and disability over time. RESULTS: Data from 33 discrete cohorts (11 166 participants) were included in the review. The variance-weighted mean pain score (out of a maximum score of 100) was 52 (95% CI 48-57) at baseline, 23 (95% CI 21-25) at 6 weeks, 12 (95% CI 9-15) at 26 weeks and 6 (95% CI 3-10) at 52 weeks after the onset of pain for cohorts with acute pain. Among cohorts with persistent pain, the variance-weighted mean pain score (out of 100) was 51 (95% CI 44-59) at baseline, 33 (95% CI 29-38) at 6 weeks, 26 (95% CI 20-33) at 26 weeks and 23 (95% CI 16-30) at 52 weeks after the onset of pain. The course of disability outcomes was similar to the time course of pain outcomes in the acute pain cohorts, but the pain outcomes were slightly worse than disability outcomes in the persistent pain cohorts. INTERPRETATION: Patients who presented with acute or persistent low-back pain improved markedly in the first six weeks. After that time improvement slowed. Low to moderate levels of pain and disability were still present at one year, especially in the cohorts with persistent pain.
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Systematic Reviews in Health Care: Meta‐Analysis in Context
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Chapter 3 European guidelines for the management of acute nonspecific low back pain in primary care
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Acute low back pain: systematic review of its prognosis
Pengel, L. H. M., Herbert, R. D., Maher, C. G., & Refshauge, K. M. (2003) · BMJ · doi:10.1136/bmj.327.7410.323 · Cited by 872
Self-citationSystematic reviews of evaluations of prognostic variables
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Will this patient develop persistent disabling low back pain?
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Cited by
What low back pain is and why we need to pay attention
Hartvigsen, J., Hancock, M. J., Kongsted, A., Louw, Q., Ferreira, M. L., Genevay, S., Hoy, D., Karppinen, J., Pransky, G., Sieper, J., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30480-x · Cited by 4,652
Self-citationMaher, C., Underwood, M., & Buchbinder, R. (2017) · The Lancet · doi:10.1016/s0140-6736(16)30970-9 · Cited by 2,535
Self-citationVlaeyen, J. W. S., Maher, C. G., Wiech, K., Van Zundert, J., Meloto, C. B., Diatchenko, L., Battié, M. C., Goossens, M., Koes, B., & Linton, S. J. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0052-1 · Cited by 497
Self-citationMotor control exercise for chronic non-specific low-back pain
Saragiotto, B. T., Maher, C. G., Yamato, T. P., Costa, L. O., Menezes Costa, L. C., Ostelo, R. W., & Macedo, L. G. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012004 · Cited by 433
Self-citationEfficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial
Williams, C. M., Maher, C. G., Latimer, J., McLachlan, A. J., Hancock, M. J., Day, R. O., & Lin, C.-W. C. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60805-9 · Cited by 325
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Metadata
- Authors
- Menezes Costa, L. D. C., Maher, C. G., Hancock, M. J., McAuley, J. H., Herbert, R. D., & Costa, L. O. P.
- Venue
- Canadian Medical Association Journal
- Publisher
- CMA Impact Inc.
- Published
- 2012-05-14
- Volume
- 184
- Issue
- 11
- Pages
- E613-E624
- ISSN
- 0820-3946 (ISSN-L)
- 1488-2329
- OpenAlex
- W2141058036
- Cited by
- 624
- References
- 52
- FWCI
- 4.27
- Type
- journal article
- Language
- en
- Open access
- gold
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