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Cited by 267

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Cardiopulmonary Exercise Testing: Basics of Methodology and Measurements

Mezzani, Alessandro·2017·Annals of the American Thoracic Society

Abstract

Cardiopulmonary exercise testing adds measurement of ventilation and volume of oxygen uptake and exhaled carbon dioxide to routine physiological and performance parameters obtainable from conventional exercise testing, furnishing an all-around vision of the systems involved in both oxygen transport from air to mitochondria and its use during exercise. Peculiarities of cardiopulmonary exercise testing methodology are the use of ramp protocols and calibration procedures for flow meters and gas analyzers. Among the several parameters provided by this technique, peak oxygen uptake, first and second ventilatory thresholds, respiratory exchange ratio, oxygen pulse, slope of ventilation divided by exhaled carbon dioxide relationship, exercise oscillatory ventilation, circulatory power, and partial pressure of end-tidal carbon dioxide are among the most relevant in the clinical setting. The choice of parameters to be considered will depend on the indication to cardiopulmonary exercise testing in the individual subject or patient, namely, exercise tolerance assessment, prognostic stratification, training prescription, treatment efficacy evaluation, diagnosis of causes of unexplained exercise tolerance reduction, or exercise (patho)physiology evaluation for research purposes. Overall, cardiopulmonary exercise testing is a methodology now widely available and supported by sound scientific evidence. Despite this, its potential still remains largely underused. Strong efforts and future investigations are needed to address these issues and further promote the use of cardiopulmonary exercise testing in the clinical and research setting.

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Metadata

Authors
Mezzani, A.
Venue
Annals of the American Thoracic Society
Published
2017-07-01
Volume
14
Issue
Supplement_1
Pages
S3-S11
ISSN
  • 2325-6621 (ISSN-L)
  • 2329-6933
OpenAlex
W2615003157
Cited by
267
References
39
FWCI
14.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cardiopulmonary Exercise Testing: Basics of Methodology and Measurements. https://app.cochat.ai/papers/10.1513/annalsats.201612-997fr
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Mezzani, A. (2017). Cardiopulmonary Exercise Testing: Basics of Methodology and Measurements. Annals of the American Thoracic Society. https://doi.org/10.1513/annalsats.201612-997fr

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