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Cited by 314

The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.

Reactive Sulfur Species: An Emerging Concept in Oxidative Stress

Giles, G.I., Jacob, C.·2002·Biological Chemistry

Abstract

The ingredients of oxidative stress include a variety of reactive species such as reactive oxygen and reactive nitrogen species (ROS, RNS). While sulfur is usually considered as part of cellular antioxidant systems there is mounting evidence that reactive sulfur species (RSS) with stressor properties similar to the ones found in ROS are formed under conditions of oxidative stress. Thiols as well as disulfides are easily oxidised to sulfur species with sulfur in higher oxidation states. Such agents include thiyl radicals, disulfides, sulfenic acids and disulfide-S-oxides. They rapidly oxidise and subsequently inhibit thiol-proteins and enzymes and can be considered as a separate class of oxidative stressors providing new antioxidant drug targets.

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Metadata

Authors
Giles, G. I., & Jacob, C.
Venue
Biological Chemistry
Published
2002-01-12
Volume
383
Issue
3-4
Pages
375-88
ISSN
1431-6730 (ISSN-L)
OpenAlex
W2016947117
Cited by
314
References
75
FWCI
2.92
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Reactive Sulfur Species: An Emerging Concept in Oxidative Stress. https://app.cochat.ai/papers/10.1515/bc.2002.042
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Giles, G. I., & Jacob, C. (2002). Reactive Sulfur Species: An Emerging Concept in Oxidative Stress. Biological Chemistry. https://doi.org/10.1515/bc.2002.042

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.