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Cited by 1,306

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Biochemistry of Oxidative Stress

Sies, Helmut·1986·Angewandte Chemie International Edition in English

Abstract

As a normal attribute of aerobic life, structural damage to organic compounds of a wide variety (DNA, proteins, carbohydrates and lipids) may occur as a consequence of oxidative reactions. Oxidative damage inflicted by reactive oxygen species has been called “oxidative stress”. Biological systems contain powerful enzymatic and nonenzymatic antioxidant systems, and oxidative stress denotes a shift in the prooxidant/antioxidant balance in favor of the former. Diverse biological processes such as inflammation, carcinogenesis, ageing, radiation damage and photobiological effects appear to involve reactive oxygen species. This field of research provides new perspectives in biochemical pharmacology, toxicology, radiation biochemistry as well as pathophysiology.

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Metadata

Authors
Sies, H.
Venue
Angewandte Chemie International Edition in English
Publisher
Wiley
Published
1986-12
Volume
25
Issue
12
Pages
1058-1071
ISSN
0570-0833 (ISSN-L)
OpenAlex
W2151639536
Cited by
1,306
References
4
FWCI
17.15
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Biochemistry of Oxidative Stress. https://app.cochat.ai/papers/10.1002/anie.198610581
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Sies, H. (1986). Biochemistry of Oxidative Stress. Angewandte Chemie International Edition in English. https://doi.org/10.1002/anie.198610581

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.