The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The Magnetofection Method: Using Magnetic Force to Enhance Gene Delivery
Abstract
In order to enhance and target gene delivery we have previously established a novel method, termed magnetofection, which uses magnetic force acting on gene vectors that are associated with magnetic particles. Here we review the benefits, the mechanism and the potential of the method with regard to overcoming physical limitations to gene delivery. Magnetic particle chemistry and physics are discussed, followed by a detailed presentation of vector formulation and optimization work. While magnetofection does not necessarily improve the overall performance of any given standard gene transfer method in vitro, its major potential lies in the extraordinarily rapid and efficient transfection at low vector doses and the possibility of remotely controlled vector targeting in vivo.
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Citations
Cites
Ogris, M., Brunner, S., Schüller, S., Kircheis, R., & Wagner, E. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300900 · Cited by 1,178
Cited by
Non-viral vectors for gene-based therapy
Yin, H., Kanasty, R. L., Eltoukhy, A. A., Vegas, A. J., Dorkin, J. R., & Anderson, D. G. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3763 · Cited by 3,123
Progress in applications of magnetic nanoparticles in biomedicine
Pankhurst, Q. A., Thanh, N. T. K., Jones, S. K., & Dobson, J. (2009) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/42/22/224001 · Cited by 1,455
Ambasta, R. K., Kumar, P., Griendling, K. K., Schmidt, H. H. H. W., Busse, R., & Brandes, R. P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m406486200 · Cited by 541
Iron Oxide Nanoparticles for Magnetically-Guided and Magnetically-Responsive Drug Delivery
Estelrich, J., Escribano, E., Queralt, J., & Busquets, M. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16048070 · Cited by 532
Advances in magnetofection—magnetically guided nucleic acid delivery
Schillinger, U., Brill, T., Rudolph, C., Huth, S., Gersting, S., Krötz, F., Hirschberger, J., Bergemann, C., & Plank, C. (2005) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2005.01.032 · Cited by 158
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Metadata
- Authors
- Plank, C., Schillinger, U., Scherer, F., Bergemann, C., Rémy, J.-S., Krötz, F., Anton, M., Lausier, J., & Rosenecker, J.
- Venue
- Biological Chemistry
- Publisher
- Walter de Gruyter GmbH
- Published
- 2003-01-15
- Volume
- 384
- Issue
- 5
- Pages
- 737-47
- ISSN
- 1431-6730 (ISSN-L)
- OpenAlex
- W2002206025
- Cited by
- 369
- References
- 1
- FWCI
- 3.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- Plank, C., Schillinger, U., Scherer, F., Bergemann, C., Rémy, J.-S., Krötz, F., Anton, M., Lausier, J., & Rosenecker, J. (2003). The Magnetofection Method: Using Magnetic Force to Enhance Gene Delivery. Biological Chemistry. https://doi.org/10.1515/bc.2003.082
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