The role of CREB signaling in Alzheimer’s disease and other cognitive disorders
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Items 201–300 of 316
- Hypothesis on ontogenesis and pathophysiology of Alzheimer’s diseaseEduarda Dal Pisol Schwab, Ruliam Queiroz, Anne Karine Bosetto Fiebrantz, Murilo Bastos, Juliana Sartori Bonini, Weber Cláudio Francisco Nunes da Silva · 2022 · Einstein (São Paulo)
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- Activation of ERα and/or ERβ ameliorates cognitive impairment and apoptosis in streptozotocin-induced diabetic miceSusu Tang, Yi Athena Ren, Lijie Xu, Jingran Cao, Hao Hong, Hui Ji, Qinghua Hu · 2018 · Hormones and Behavior
- Structural and functional characterization of H2 haplotype MAPT promoter: Unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's diseaseBryan Maloney, Debomoy K. Lahiri · 2012 · Gene
- Bioinformatics analyses of significant genes, related pathways and candidate prognostic biomarkers in Alzheimer’s diseaseBasavaraj Mallikarjunayya Vastrad, Chanabasayya Mallikarjunayya Vastrad · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Effects of sesamin on Aβ1-42-induced oxidative stress and LTP impairment in a rat model of Alzheimer's diseaseAmir Arabi, Seyed Asaad Karimi, Iraj Salehi, Rasool Haddadi, Alireza Komaki · 2023 · Metabolic Brain Disease
- The protective effects of Irbesartan in cognitive impairment in hypertensionShengyun Hao, He Qian, Yuan Yuan, Qiong Mu · 2024 · Aging
- Uptake and Cellular Effects of Polymethylmethacrylate on Human Cell LinesArthur Braun, Harald Seitz · 2024 · Microplastics
- Single-Cell Cortical Transcriptomics Reveals Common and Distinct Changes in Cell-Cell Communication in Alzheimer’s and Parkinson’s DiseaseSophie Le Bars, Enrico Glaab · 2024 · Molecular Neurobiology
- The effect of maternal forced exercise on offspring pain perception, motor activity and anxiety disorder: the role of 5-HT2 and D2 receptors and CREB gene expressionOzra Motaghinejad, Majid Motaghinejad, Manijeh Motevalian, Fatemeh Rahimi‐Sharbaf, Tabassom Beiranvand · 2017 · Journal of Exercise Rehabilitation
- Extracts of Sideritis scardica and Clinopodium vulgare Alleviate Cognitive Impairments in Scopolamine-Induced Rat DementiaMaria I. Lazarova, Elina R. Tsvetanova, Almira P. Georgieva, Miroslava O. Stefanova, Diamara N. Uzunova, Petko Nedyalkov Denev, Valya Vassileva, Krasimira N. Tasheva · 2024 · International Journal of Molecular Sciences
- Rubus coreanus Miquel Ameliorates Scopolamine-Induced Memory Impairments in ICR MiceMi‐Ran Choi, Min Young Lee, Ji Eun Hong, Jeong Eun Kim, Jae Yong Lee, Tae‐Hwan Kim, Jang-Woo Chun, Hyun Kyung Shin, Eun Ji Kim · 2014 · Journal of Medicinal Food
- N-Methyl-D-Aspartate (NMDA) Receptor Antagonists and their Pharmacological Implication: A Medicinal Chemistry-oriented Perspective OutlineVikas Rana, Shayantan Ghosh, Akanksha Bhatt, Damini Bisht, Gaurav Joshi, Priyank Purohit · 2024 · Current Medicinal Chemistry
- 7-Deoxy-trans-dihydronarciclasine Reduces β-Amyloid and Ameliorates Memory Impairment in a Transgenic Model of Alzheimer’s DiseaseYoon Sun Chun, Lijun Zhang, Huan Li, Yurim Park, Sungkwon Chung, Hyun Ok Yang · 2018 · Molecular Neurobiology
- Neuroprotective effects of novel compound FMDB on cognition, neurogenesis and apoptosis in APP/PS1 transgenic mouse model of Alzheimer's diseaseXiaoqian Ren, Xin Huang, Shu-Yun Xing, Yan Long, Dan-Hua Yuan, Hao Hong, Susu Tang · 2023 · Neurochemistry International
- Scaffold hopping strategy toward novel Pyrazolo[3,4-d]pyrimidine-based thiazole frameworks as potential cholinesterase inhibitors for treating Alzheimer’s disease: insight into in vitro and in silico approachesFakhria A. Al‐Joufi, Maher S. Alwethaynani, Hina Sarfraz, Faisal Asif, Rafaqat Hussain, Asma Sardar, Yousaf Khan, Fakhrul Hassan, Ammena Y. Binsaleh, Nawal Al‐Hoshani et al. · 2026 · Journal of Molecular Structure
- Chronic administration of Tat-GluR23Y ameliorates cognitive dysfunction targeting CREB signaling in rats with amyloid beta neurotoxicityFatemeh Ashourpour, Adele Jafari, Parvin Babaei · 2021 · Metabolic Brain Disease
- Exploring the memory: existing activity-dependent tools to tag and manipulate engram cellsBo Pang, Xiaoyan Wu, Hailun Chen, Yiwen Yan, Zibo Du, Zihan Yu, Xiai Yang, Wanshan Wang, Kangrong Lu · 2024 · Frontiers in Cellular Neuroscience
- Differential Effects of Human P301L Tau Expression in Young versus Aged MiceHolly C. Hunsberger, Sharay E. Setti, Carolyn C. Rudy, Daniel S. Weitzner, Jeremiah C. Pfitzer, Kelli L. McDonald, Hao Hong, Subhrajit Bhattacharya, Vishnu D. Suppiramaniam, Miranda N. Reed · 2021 · International Journal of Molecular Sciences
- Pomegranate and Cognitive Performance: A Systematic ReviewRoghayeh Molani‐Gol, Elaheh Foroumandi, Mohammad Alizadeh, Sorayya Kheirouri · 2023 · Current Pharmaceutical Design
- Chronic Sleep Deprivation Altered the Expression of Memory-Related Genes and Caused Cognitive Memory Dysfunction in MiceXiang Wang, Hanqing Chen, Tian Tang, Xiang Zhan, Shukui Qin, Taijun Hang, Min Song · 2024 · International Journal of Molecular Sciences
- Computational investigation of mechanistic insights of Aβ42 interactions against extracellular domain of nAChRα7 in Alzheimer’s diseaseMubashir Hassan, Saba Shahzadi, Hussain Raza, Muhammad Athar Abbasi, Hany Alashwal, Nazar Zaki, Ahmed A. Moustafa, Sung‐Yum Seo · 2018 · International Journal of Neuroscience
- High Mobility Group Box 1 Ameliorates Cognitive Impairment in the 3×Tg-AD Mouse ModelJin Chi Zhang, Xuefeng Hua, Jin‐Hua Gu, Feng Chen, Jianlan Gu, Cheng‐Xin Gong, Fei Liu, Chun‐Ling Dai · 2020 · Journal of Alzheimer s Disease
- Protective Effects of Combination of Carthamus tinctorius L. Seed and Taraxacum coreanum on Scopolamine-induced Memory Impairment in MiceJi Hyun Kim, Mei Tong He, Min Jo Kim, Chan Hum Park, Jae Yang Lee, Yu Su Shin, Eun Ju Cho · 2020 · Korean Journal of Medicinal Crop Science
- Synchronized genetic activities in Alzheimer’s brains revealed by heterogeneity-capturing network analysisSharlee Climer, Alan R. Templeton, Michael R. Garvin, Daniel Jacobson, Matthew J. Lane, Scott Hulver, Brittany H. Scheid, Zheng Chen, Carlos Cruchaga, Weixiong Zhang · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Recognition of the CREB-Binding Protein/Mixed Lineage Leukemia Interface by Sulfonyl-γ-AApeptides: Beyond Mimicry of Mixed Lineage LeukemiaBo Huang, Minghui Wang, Emily Gregory‐Lott, Bingbing X. Li, Yu Yu Win, Ning Shen, Jianyu Chen, Sihao Li, Chuanhai Cao, Xiangshu Xiao et al. · 2025 · Journal of Medicinal Chemistry
- Resveratrol-Loaded Pluronic Micelles Ameliorate Scopolamine-Induced Cognitive Dysfunction Targeting Acetylcholinesterase Activity and Programmed Cell DeathMaria I. Lazarova, Miroslava O. Stefanova, Elina R. Tsvetanova, Almira P. Georgieva, Krasimira N. Tasheva, Lyubomira Radeva, Krassimira Yoncheva · 2024 · International Journal of Molecular Sciences
- Lindera glauca Blume ameliorates amyloid-β1-42-induced memory impairment in mice with neuroprotection and activation of the CREB-BDNF pathwayYunna Kim, Seung‐Hun Cho · 2021 · Neurochemistry International
- Insights into RNA ‐mediated pathology in new mouse models of Huntington's diseaseM. Woźna, Magdalena Jazurek, Łukasz Przybył, Dorota Wronka, Julia Oliwia Misiorek, Joanna Suszyńska-Zajczyk, Grzegorz Figura, Adam Ciesiołka, Paula Sobieszczańska, Anna Zeller et al. · 2024 · The FASEB Journal
- Hormonal Sensitivity of Adenylyl Cyclase in the Myocardium, Brain and Testes of 18-month-old Non-Diabetic and Diabetic RatsAlexander Olegovich Shpakov · 2013 · International Journal of Biochemistry Research & Review
- Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart diseaseGeorge C. Gabriel, Hisato Yagi, Tuantuan Tan, Abha Singh Bais, Benjamin J. Glennon, Margaret Caroline Stapleton, Lihua Huang, William T. Reynolds, Marla G. Shaffer, Madhavi K. Ganapathiraju et al. · 2025 · Nature Communications
- Exploring the Neuroprotective Effects of Rufinamide in a Streptozotocin-Induced Dementia ModelDarshpreet Kaur, Amarjot Kaur Grewal, Dalia Fouad, Amit Kumar, Varinder Singh, Athanasios T. Alexiou, Marios Papadakis, Gaber El‐Saber Batiha, Nermeen N. Welson, Thakur Gurjeet Singh · 2024 · Cellular and Molecular Neurobiology
- From Better Diagnostics to Earlier Treatment: The Rapidly Evolving Alzheimer’s Disease LandscapeAnastasia M. Bougea, Manuel Debasa‐Mouce, Shelly Gulkarov, Mónica Castro‐Mosquera, Allison Bethanne Reiss, Alberto Ouro · 2025 · Medicina
- Unraveling the Mechanism of Immunity and Inflammation Related to Molecular Signatures Crosstalk Among Obesity, T2D, and AD: Insights From Bioinformatics ApproachesVishal Kumar, Piplu Bhuiyan, Junxia Qi, Yang Chen, Jubiao Zhang, Fen Yang, Juxue Li · 2023 · Bioinformatics and Biology Insights
- Electroacupuncture attenuates ketamine-induced neuronal injury in the locus coeruleus of rats through modulation of the CAMK II/CREB pathwayHuachun Miao, Runzhi Li, Wenjuan Li, Feng Wu, Huaibin Li, Hong Luo · 2023 · Brain Research Bulletin
- Water extract of Humulus japonicus improves age‑related cognitive decline by inhibiting acetylcholinesterase activity and the acetylcholine signaling pathwayJu-Eun Kim, Kyeong-Seon Min, Jun Go, Hye‐Yeon Park, Young‐Keun Choi, In-Bok Lee, Jaewon Shin, Hyun‐Ju Cho, Hong‐Sik Kim, Dae Youn Hwang et al. · 2025 · Molecular Medicine Reports
- Cilostazol and SB203580 combination: Targeting ER stress and p38MAPK signaling in Alzheimer's disease mouse modelMohamed Ashraf Ali, Rabab Hamed Sayed, Walaa Wadie, Reham Atef Mohammed · 2025 · European Journal of Pharmacology
- The Pathogenesis Mechanism, Structure Properties, Potential Drugs and Therapeutic Nanoparticles against the Small Oligomers of Amyloid-βKe Wang, Liu Na, Mojie Duan · 2020 · Current Topics in Medicinal Chemistry
- MtDNA‐depleted neuronal cell transcriptomes reveal Alzheimer's disease‐related changesBlaise W. Menta, Emily Schueddig, Amol Ranjan, Yanming Li, Shea J. Andrews, Heather Wilkins, Dong Pei, Russell Howard Swerdlow · 2025 · Alzheimer s & Dementia
- Neuroprotective Effect of Ixeris dentata Extract on Trimethyltin-Induced Memory Impairment in RatsMinsook Ye, Daehyuk Jang, Sun‐Young Lee, Kyu-Ri Kim, Sung Ja Rhie, Jin Kyung Oh, Insop Shim · 2024 · Current Issues in Molecular Biology
- A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell deathGuilherme M. Gomes, Julia Bär, Anna Karpova, Michael R. Kreutz · 2023 · Molecular Brain
- Adsorption behaviour on silver nanocolloids at various concentrations of a bioactive therapeutic derivative of methylhydrazine: Experimental, DFT and molecular docking investigationsJamelah Saleh Al-Otaibi, Yohannan Sheena Mary, Y. Shyma Mary, Martin Krátký, Jarmila Vinšová, K. Jalaja, Maria Cristina Gamberini · 2023 · Journal of Molecular Liquids
- Anti-Cognitive Decline by Yinxing-Mihuan-Oral-Liquid via Activating CREB/BDNF Signaling and Inhibiting Neuroinflammatory ProcessZhenting Huang, Chengqun Wan, Yangyang Wang, Qiao Peifeng, Qian Zou, Jingxi Ma, Zhou Liu, Zhiyou Cai · 2021 · Experimental Aging Research
- Modeling the short time-scale dynamics of β-amyloid–neuron interactionsNatasha Wilson, Bradford Gates, Mariajosé Castellanos · 2013 · Journal of Theoretical Biology
- Predicting and Monitoring Responses to Epigenetic DrugsSemira Sheikh, Mina Bekheet, Heidi Olzscha, Nicholas Barrie La Thangue · 2016 · Elsevier eBooks
- Advances at the intersection of normal brain aging and Alzheimer’s diseaseSarah M. Neuner, Lynda A. Wilmott, Corina Burger, Catherine Cook Kaczorowski · 2017 · Behavioural Brain Research
- Mulberroside A: A Multi-Target Neuroprotective Agent in Alzheimer’s Disease via Cholinergic Restoration and PI3K/AKT Pathway ActivationJin Li, Jiawen Wang, Yaodong Li, Jingyi Guo, Ziliang Jin, Shourong Qiao, Yunxia Zhang, Guoyin Li, Huazhen Liu, Changjing Wu · 2025 · Biology
- Discovery of a brain penetrant SGK1 inhibitor using a ligand- and structure-based virtual screening methodologyEnrique Madruga, Cecilia Sanchez-Santos, Ignacio Martı́nez, David Ramírez, Carmen Gil, Ana Martı́nez · 2025 · Journal of Enzyme Inhibition and Medicinal Chemistry
- Subtle Alterations in Hippocampal Neuronal Activity Coincide With Early Sex‐Specific Differences in Amyloidosis and Microglia in a Pre‐Symptomatic Mouse Model of Alzheimer‐Like PathologyThomas Chaigneau, Sha Sha, Candice M. Roux, Saba Aïd, Alice Faucher, Yannick Chantran, Guillaume Dorothée, Slavica M Krantic · 2025 · Glia
- Integrating spatial transcriptomics and snRNA-seq data enhances differential gene expression analysis results of AD-related phenotypesShizhen Tang, Shihan Liu, Aron S. Buchman, David Alan Bennett, Philip L. De Jager, Jingjing Yang, Jian Hu · 2025 · Human Genetics and Genomics Advances
- A Cross-sectional In Vitro Study on the Synergistic Neuroprotective Effects of Phytochemicals Ferulic Acid and Ginkgolide B against Amyloid Beta-induced Oxidative Stress and Modulation of Multifunctional Enzyme APE1/Ref-1 in Human Neuroblastoma SH-SY5Y CellsHarkomal Verma, Anuradha Yadav, Prabhakar Gangwar, Sharanjot Kaur, Puneet Kumar, Monisha Dhiman, Anil Kumar Mantha · 2025 · Cell Biochemistry and Biophysics
- CREB Regulates Cisplatin Resistance by Targeting TNKS and KDM6A in NSCLC cell-Derived Tumor SpheroidJi Hae Lee, Youngjoo Kwon, Kyungsil Yoon · 2025 · International Journal of Biological Sciences
- Deciphering the molecular mechanism of REST regulation through DEGs and TFs in Alzheimer's diseaseAjmal Nassar, Madhavan Nampoothiri, Prasada Chowdari Gurram, Sairaj Satarker, Dinesh Upadhya, Gayathri Shamabhat, Fayaz Shaik Mahammad · 2023 · Journal of Applied Pharmaceutical Science
- Sericin Improves Memory Impairment Via Activation of the PKA-CREB-BDNF Signaling Pathway and Suppression of Oxidative Stress in Ovariectomized MiceFereshteh Farajdokht, Saeed Sadigh‐Eteghad, Seyed Mehdi Vatandoust, Leila Hosseini, Soroush Morsali, Hamidreza Feizi, Pedram Ghaderi Shadbad, Javad Mahmoudi · 2024 · Neurochemical Research
- Signaling pathways in the treatment of Alzheimer’s disease with acupuncture: a narrative reviewChao Ke, Shengtao Shan, Yan Tan, Yang Cao, Zhengrong Xie, Senjie Shi, Jiang Pan, Wei Zhang · 2024 · Acupuncture in Medicine
- Maternal Zinc Diet Impairs Learning and Memory in Offspring Rats through the CREB/BDNF PathwayNovi Dewi Tanjung, Nieka Adhara Wahono, Ninik Mudjihartini, Ani Retno Prijanti · 2024 · The Indonesian Biomedical Journal
- Potential Therapeutic Targets for Improving Memory Impairments and Dementia: Clues Obtained from Memory-Enhanced MiceShogo Endo · 2012 · Springer eBooks
- The beneficial effects of Achyranthus bidentata Blume on scopolamine-induced memory impairment in miceSarang Oh, Eun‐Mi Ahn, Ji Wook Jung · 2011 · Oriental Pharmacy and Experimental Medicine
- The regulatory role of Gnao1 protein in diabetic encephalopathy in KK-Ay mice and streptozotocin-induced diabetic ratsShuhong Xu, Wenwen Yu, Xiang Zhang, Weiping Wang, Xiaoliang Wang · 2022 · Brain Research
- Preventing Jacob-induced transcriptional inactivation of CREB protects synapses from β-amyloid in Alzheimer’s DiseaseKatarzyna M. Grochowska, Guilherme M. Gomes, Rajeev Raman, Rahul Kaushik, Liudmila Sosulina, Hiroshi Kaneko, Anja M. Oelschlegel, PingAn Yuanxiang, Irene Reyes-Resina, Gonca Bayraktar et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Does Metabolic Manager Show Encouraging Outcomes in Alzheimer's?: Challenges and Opportunity for Protein Tyrosine Phosphatase 1b InhibitorsRitu Singh, Smita Jain, Vartika Paliwal, Kanika Verma, Sarvesh Paliwal, Swapnil K. Sharma · 2024 · Drug Development Research
- Alpha-Pinene Ameliorates Memory Deficits in 3-Nitropropionic Acid-Induced Rat Model of Huntington’s DiseaseParia Hashemi, Mohammad Raman Moloudi, Helia Rahmani, Katayoun Hassanzadeh, Zakaria Vahabzadeh, Esmael Izadpanah · 2025 · Neurochemical Research
- The absence of Parkin in hTau mice leads to synaptic mitochondrial dysfunction, alterations to the synaptic proteome, and increased phosphorylated tau in the HippocampusL. Daniel Estrella, Xiaoke Xu, Collin White, Jane E. Manganaro, Lexi Sheldon, Trey Farmer, Kelly L. Stauch · 2025 · Neurobiology of Disease
- miR ‐769‐5p as a Novel Biomarker and Functional Mediator in Alzheimer's Disease: Targeting CREB5 to Alleviate Oxidative InjuryPengju Ma, Huanxi Cui, Lihong Ren, Yumei Liu, Meini Cen · 2026 · Apmis
- Interpretable integration of unpaired multi-omics for Alzheimer’s diagnosis via cross-modal transformer reconstructionKai Liao, Danfeng Du, Jiawei Li, Jian An Huang, Xiaodan Fan, Changshui Chen, Shanshan Wu, Bowei Yan, Haibo Li · 2026 · PLoS Computational Biology
- Effect specificity of the early intervention with moxibustion at “BL23” in Alzheimer's disease rats modeled by ovariectomy and D-Galactose injection 艾灸“肾俞”早期干预去卵巢合D-半乳糖注射AD样大鼠效应中的特异性Yanjun Du, Yiming Tao, Qing Tian, Peng Hui Zeng, Wen-hui WU, Jia-huan Xiao · 2020 · 世界针灸杂志:英文版
- Prioritizing Nrf2/HO-1-Mediated Intrinsic Antioxidant Upregulation: The Foremost Neuroprotective Mechanism of Melittin in a Scopolamine-Induced Animal Model of Neural Stress, Preceding Anti- Inflammatory EffectsJaehee Yoo, Cong Duc Nguyen, Sang Jun Jeong, Ji Hye Yang, Gihyun Lee, Jeong Cheol Shin, Jae‐Hong Kim · 2024 · Research Square
- Identifying the function of methylated genes in Alzheimer’s disease to determine epigenetic signatures: a comprehensive bioinformatics analysisMd Rezanur Rahman, Tania Islam, Esra Göv, Julian M.W. Quinn, Mohammad Ali Moni · 2021 · Experimental Results
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- Single-Cell Transcriptomic Analysis by Deep Learning Identifies Novel Microglial Transcription Regulations in Alzheimer’s DiseaseMaitry Ronakbhai Trivedi, Jay Shah, Yi Su, Eric M. Reiman, Teresa Wu, Qi Wang · 2026 · AI in neuroscience.
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- Coupling extrasynaptic NMDA receptors to aberrant intracellular signaling in Huntington diseaseAlejandro Dau · 2013 · cIRcle (University of British Columbia)
- Age-related impairments in memory and in cholinergic signaling due to reduced blood glucose responses to epinephrineKenneth A. Morris · 2012 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
- Nitrate Chimeras: A New Class of Disease Modifying Agents for the Treatment of Alzheimer's DiseaseLawren A. VandeVrede · 2014 · Figshare
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- A Jacob/nsmf gene knockout does not protect against hypoxia- and NMDA-induced neuronal cell deathGuilherme M. Gomes, Julia Bär, Anna Karpova, Michael R. Kreutz · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Picking the best isoformDean Paes · 2023 · Research Publications (Maastricht University)
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