The role of CREB signaling in Alzheimer’s disease and other cognitive disorders

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Items 101–200 of 316

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3. Nr4a2 Transcription Factor in Hippocampal Synaptic Plasticity, Memory and Cognitive Dysfunction: A Perspective Review
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4. Nutraceuticals to promote neuronal plasticity in response to corticosterone-induced stress in human neuroblastoma cells
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5. ERα and/or ERβ activation ameliorates cognitive impairment, neurogenesis and apoptosis in type 2 diabetes mellitus mice
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6. Bay Leaf (Laurus Nobilis L.) Incense Improved Scopolamine-Induced Amnesic Rats by Restoring Cholinergic Dysfunction and Brain Antioxidant Status
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7. Artificial Intelligence and Circulating Cell-Free DNA Methylation Profiling: Mechanism and Detection of Alzheimer’s Disease
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8. A Gating Mutation in Ryanodine Receptor Type 2 Rescues Phenotypes of Alzheimer’s Disease Mouse Models by Upregulating Neuronal Autophagy
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9. Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease
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10. 7,8-Dihydroxycoumarin Alleviates Synaptic Loss by Activated PI3K-Akt-CREB-BDNF Signaling in Alzheimer’s Disease Model Mice
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11. SCM-198 Ameliorates Cognitive Deficits, Promotes Neuronal Survival and Enhances CREB/BDNF/TrkB Signaling without Affecting Aβ Burden in AβPP/PS1 Mice
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12. Assessment of the CYP1A2 Inhibition-Mediated Drug Interaction Potential for Pinocembrin Using In Silico , In Vitro , and In Vivo Approaches
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13. Jacob‐induced transcriptional inactivation of CREB promotes Aβ‐induced synapse loss in Alzheimer's disease
    Katarzyna M. Grochowska, Guilherme M. Gomes, Rajeev Raman, Rahul Kaushik, Liudmila Sosulina, Hiroshi Kaneko, Anja Maria Oelschlegel, PingAn Yuanxiang, Irene Reyes‐Resina, Gonca Bayraktar et al. · 2023 · The EMBO Journal
14. Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies
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15. Melatonin ameliorates cognitive memory by regulation of cAMP-response element-binding protein expression and the anti-inflammatory response in a rat model of post-traumatic stress disorder
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16. Angelica keiskei Ameliorates Scopolamine-Induced Memory Impairments in Mice
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18. Compartmentalized Signaling in Aging and Neurodegeneration
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19. Chronic scopolamine-injection-induced cognitive deficit on reward-directed instrumental learning in rat is associated with CREB signaling activity in the cerebral cortex and dorsal hippocampus
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20. Comparison of the effect of three licorice varieties on cognitive improvementviaan amelioration of neuroinflammation in lipopolysaccharide-induced mice
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21. Pharmacological Potential of Cilostazol for Alzheimer’s Disease
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22. Design, synthesis, and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer’s disease
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23. Proof‐of‐Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase‐4 in Cognitively Healthy Subjects: Implications for Alzheimer’s Dementia
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24. From Age-Related Cognitive Decline to Alzheimer’s Disease: A Translational Overview of the Potential Role for Phosphodiesterases
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25. Melatonin Improves Short-Term Spatial Memory in a Mouse Model of Alzheimer’s Disease
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26. Cognitive Enhancers (Nootropics). Part 3: Drugs Interacting with Targets other than Receptors or Enzymes. Disease-modifying Drugs
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27. P7C3 Attenuates the Scopolamine-Induced Memory Impairments in C57BL/6J Mice
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28. Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease
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30. Decoding Common Features of Neurodegenerative Disorders: From Differentially Expressed Genes to Pathways
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31. Aqueous extract from You-Gui-Yin ameliorates cognitive impairment of chronic renal failure mice through targeting hippocampal CaMKIIα/CREB/BDNF and EPO/EPOR pathways
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32. Understanding of Alzheimer's disease pathophysiology for therapeutic implications of natural products as neuroprotective agents
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33. Cognitive‐Enhancing Effect of Aronia melanocarpa Extract against Memory Impairment Induced by Scopolamine in Mice
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34. Memory Disorders Related to Hippocampal Function: The Interest of 5-HT4Rs Targeting
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35. RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease
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36. Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer’s disease
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37. A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility
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38. Studies on medicinal herbs for cognitive enhancement based on the text mining of Dongeuibogam and preliminary evaluation of its effects
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39. Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells
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40. Insights into dietary phytochemicals targeting Parkinson's disease key genes and pathways: A network pharmacology approach
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42. Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology
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43. Design, Synthesis, and Biological Investigation of Quinazoline Derivatives as Multitargeting Therapeutics in Alzheimer’s Disease Therapy
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44. The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells
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45. The Melatonin Signaling Pathway in a Long-Term Memory In Vitro Study
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46. Mining disease genes using integrated protein–protein interaction and gene–gene co‐regulation information
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47. Cyclic Nucleotides Signaling and Phosphodiesterase Inhibition: Defying Alzheimer’s Disease
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48. A Chewable Cure “Kanna”: Biological and Pharmaceutical Properties of Sceletium tortuosum
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49. Dysregulated CRTC1-BDNF signaling pathway in the hippocampus contributes to Aβ oligomer-induced long-term synaptic plasticity and memory impairment
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50. Lead-exposure associated miRNAs in humans and Alzheimer’s disease as potential biomarkers of the disease and disease processes
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51. An insight into the concept of neuroinflammation and neurodegeneration in Alzheimer’s disease: targeting molecular approach Nrf2, NF-κB, and CREB
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52. Identification of learning-induced changes in protein networks in the hippocampi of a mouse model of Alzheimer’s disease
    Eric Ferreira, D M Shaw, Salvatore Oddo · 2016 · Translational Psychiatry
53. Neuroprotective effects of Camellia nitidissima Chi leaf extract in hydrogen peroxide‐treated human neuroblastoma cells and its molecule mechanisms
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54. Lactobacillus plantarum ST-III culture supernatant ameliorates alcohol-induced cognitive dysfunction by reducing endoplasmic reticulum stress and oxidative stress
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55. Furoxans (Oxadiazole-4N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory
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56. Walnut diets up-regulate the decreased hippocampal neurogenesis and age-related cognitive dysfunction in d -galactose induced aged rats
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59. Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain
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60. Ca2+-Permeable TRPV1 Receptor Mediates Neuroprotective Effects in a Mouse Model of Alzheimer’s Disease via BDNF/CREB Signaling Pathway
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61. CREB-Regulated Transcription Coactivator 1-Dependent Transcription in Alzheimer’s Disease Mice
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63. Synergistic enhancing-memory effect of D-serine and RU360, a mitochondrial calcium uniporter blocker in rat model of Alzheimer's disease
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64. Mulberry fruit extract alleviates the intracellular amyloid‐β oligomer‐induced cognitive disturbance and oxidative stress in Alzheimer’s disease model mice
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65. Cognitive‐Enhancing Effect of Steamed and Fermented Codonopsis lanceolata : A Behavioral and Biochemical Study
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66. Approaches for Probing Allosteric Interactions at 7 Transmembrane Spanning Receptors
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67. The role of BRD 7 in embryo development and glucose metabolism
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68. Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment
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69. Microglia CREB-Phosphorylation Mediates Amyloid-β-Induced Neuronal Toxicity
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70. Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca2+/CaMKII/CREB signaling pathway
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71. Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer’s disease
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75. In silico -determined compound from the root of Pueraria lobate alleviates synaptic plasticity injury induced by Alzheimer's disease via the p38MAPK-CREB signaling pathway
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80. A CREB1 Gene Polymorphism (rs2253206) Is Associated with Prospective Memory in a Healthy Cohort
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81. Bromodomain-Containing Protein 4: A Druggable Target
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82. Neuroprotective Effect of Cudrania tricuspidata Fruit Extracts on Scopolamine-Induced Learning and Memory Impairment
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83. Rescue of Impaired Long-Term Facilitation at Sensorimotor Synapses of<i>Aplysia</i>following siRNA Knockdown of CREB1
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84. Adenosine A1 receptor agonist, N6-cyclohexyladenosine, attenuates Huntington's disease via stimulation of TrKB/PI3K/Akt/CREB/BDNF pathway in 3-nitropropionic acid rat model
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85. Fate-mapping and functional dissection reveal perilous influence of type I interferon signaling in mouse brain aging
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86. Biomarkers in Alzheimer’s disease progression: a longitudinal cohort study of NPTX2, GRIA1, and GRIA4
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87. Genetic markers of white matter integrity in schizophrenia revealed by parallel ICA
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88. WY14643 Attenuates the Scopolamine-Induced Memory Impairments in Mice
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89. Sekikaic Acid and Lobaric Acid Target a Dynamic Interface of the Coactivator CBP/p300
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90. Presenilins Regulate Neurotrypsin Gene Expression and Neurotrypsin-dependent Agrin Cleavage via Cyclic AMP Response Element-binding Protein (CREB) Modulation*
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91. Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer’s Disease Mouse Model
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92. Muscarinic acetylcholine receptor-dependent and NMDA receptor-dependent LTP and LTD share the common AMPAR trafficking pathway
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93. Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy
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94. Rhoifolin, baicalein 5,6-dimethyl ether and agathisflavone prevent amnesia induced in scopolamine zebrafish (Danio rerio) model by increasing the mRNA expression of bdnf, npy, egr-1, nfr2α, and creb1 genes
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95. Steamed and Fermented Ethanolic Extract from Codonopsis lanceolata Attenuates Amyloid‐β‐Induced Memory Impairment in Mice
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96. Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1–42‐mediated cytotoxicity
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