Cited by 51Deep Brain Stimulation and Movement DisordersNeurological and metabolic disordersParkinson's Disease Mechanisms and Treatments

The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.

Tetrabenazine

Fasano, Alfonso, Bentivoglio, Anna Rita·2009·Expert Opinion on Pharmacotherapy

Abstract

BACKGROUND: Tetrabenazine (TBZ) depletes presynaptic dopamine in the CNS. It has been found to be beneficial in hyperkinetic movement disorders without carrying the extrapyramidal side effects that are characteristic of neuroleptics. OBJECTIVE: To summarize current knowledge on the use of TBZ and draw conclusions about its efficacy and safety. METHODS: PubMed literature searches using the term 'tetrabenazine' were carried out for the period prior to May 2009. Additional relevant studies referenced by these publications were included. CONCLUSIONS: Both short- and long-term studies have consistently yielded favorable results for the use of TBZ in the treatment of hyperkinetic movement in terms of efficacy and safety. TBZ is most effective in reducing chorea (including Huntington's disease associated chorea), tic associated with Tourette's syndrome and tardive dyskinesias. Furthermore, TBZ might also have potential for use in other hyperkinetic disorders (e.g., myoclonus and dystonia), for which future clinical trials are needed.

Overview

Integrity signals

Registry

Crossref · 10.1517/14656560903386292

Cites

77 of 77 references verified0 citation errors · 0 not checkable

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Citations

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Flagged first, then by citations

Research works printed but not linked: 6

  1. Lende N, 1960, Dis Nerv Syst, 21, 118
  2. Jankovic J, 1983, Adv Neurol, 37, 277
  3. Gimenez-Roldan S, 1989, Neurologia, 4, 282
  4. Mestre T, 2009, Cochrane Database Syst Rev, CD006456
  5. Kenney C, 2007, J Pediatric Neurol, 5, 9
  6. Jankovic J, 2004, Adv Neurol, 94, 275

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Metadata

Authors
Fasano, A., & Bentivoglio, A. R.
Affiliations
Università Cattolica del Sacro Cuore (IT)
Venue
Expert Opinion on Pharmacotherapy
Published
2009-11-25
Volume
10
Issue
17
Pages
2883-2896
ISSN
  • 1465-6566 (ISSN-L)
  • 1744-7666
OpenAlex
W4239925697
Cited by
51
References
77
Citations by year
2025: 1 · 2024: 1 · 2023: 4 · 2022: 4 · 2021: 3 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 4 · 2012: 7
FWCI
0.74
Type
journal article
Language
en
Open access
closed
Locations
  • Expert Opinion on Pharmacotherapy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
  • Health Sciences › Medicine › Clinical Neurology › Neurological and metabolic disorders
  • Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Keywords
tetrabenazine, dopamine depletion, hyperkinetic movement disorders, chorea, Huntington's disease, Tourette syndrome, tardive dyskinesia, myoclonus, dystonia, drug efficacy, drug safety, extrapyramidal symptoms
MeSH terms
Animals, Drug Interactions, Humans, Nervous System Diseases, Tetrabenazine, Randomized Controlled Trials as Topic, Adrenergic Uptake Inhibitors, Models, Animal

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