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Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application
Open accessAbstract
Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles. SLNs were developed to overcome the limitations of other colloidal carriers, such as emulsions, liposomes and polymeric nanoparticles because they have advantages like good release profile and targeted drug delivery with excellent physical stability. In the next generation of the lipid nanoparticle, NLCs are modified SLNs which improve the stability and capacity loading. Three structural models of NLCs have been proposed. These LNPs have potential applications in drug delivery field, research, cosmetics, clinical medicine, etc. This article focuses on features, structure and innovation of LNPs and presents a wide discussion about preparation methods, advantages, disadvantages and applications of LNPs by focusing on SLNs and NLCs.
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Cited by
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Role of Nanotechnology in Cosmeceuticals: A Review of Recent Advances
Kaul, S., Gulati, N., Verma, D., Mukherjee, S., & Nagaich, U. (2018) · Journal of Pharmaceutics · doi:10.1155/2018/3420204 · Cited by 435
The landscape of nanoparticle-based siRNA delivery and therapeutic development
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Metadata
- Authors
- Naseri, N., Valizadeh, H., & Zakeri-Milani, P.
- Venue
- Advanced Pharmaceutical Bulletin
- Publisher
- Maad Rayan Publishing Company
- Published
- 2015-09-19
- Volume
- 5
- Issue
- 3
- Pages
- 305-313
- ISSN
- 2228-5881 (ISSN-L)
- 2251-7308
- OpenAlex
- W2265120954
- Cited by
- 1,116
- References
- 0
- FWCI
- 19.84
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Naseri, N., Valizadeh, H., & Zakeri-Milani, P. (2015). Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application. Advanced Pharmaceutical Bulletin. https://doi.org/10.15171/apb.2015.043
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