The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Nanostructured Lipid Carriers: A Groundbreaking Approach for Transdermal Drug Delivery
Open accessAbstract
Nanostructured lipid carriers (NLCs) are novel pharmaceutical formulations which are composed of physiological and biocompatible lipids, surfactants and co-surfactants. Over time, as a second generation lipid nanocarrier NLC has emerged as an alternative to first generation nanoparticles. This review article highlights the structure, composition, various formulation methodologies, and characterization of NLCs which are prerequisites in formulating a stable drug delivery system. NLCs hold an eminent potential in pharmaceuticals and cosmetics market because of extensive beneficial effects like skin hydration, occlusion, enhanced bioavailability, and skin targeting. This article aims to evoke an interest in the current state of art NLC by discussing their promising assistance in topical drug delivery system. The key attributes of NLC that make them a promising drug delivery system are ease of preparation, biocompatibility, the feasibility of scale up, non-toxicity, improved drug loading, and stability.
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Cites
Müller, R. H., Radtke, M., & Wissing, S. A. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00118-7 · Cited by 2,113
Solid lipid nanoparticles for parenteral drug delivery
Wissing, S. A., Kayser, O., & Müller, R. H. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.12.002 · Cited by 1,495
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application
Naseri, N., Valizadeh, H., & Zakeri-Milani, P. (2015) · Advanced Pharmaceutical Bulletin · doi:10.15171/apb.2015.043 · Cited by 1,116
Solid lipid nanoparticles: A modern formulation approach in drug delivery system
Mukherjee, S., Ray, S., & Thakur, R. (2009) · Indian Journal of Pharmaceutical Sciences · doi:10.4103/0250-474x.57282 · Cited by 1,000
Recent Advances in Lipid Nanoparticle Formulations with Solid Matrix for Oral Drug Delivery
Das, S., & Chaudhury, A. (2011) · AAPS PharmSciTech · doi:10.1208/s12249-010-9563-0 · Cited by 838
Nanostructured lipid carriers (NLC) in cosmetic dermal products☆
MULLER, R., PETERSEN, R., HOMMOSS, A., & PARDEIKE, J. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.04.012 · Cited by 700
Structure of the skin barrier and its modulation by vesicular formulations
Bouwstra, J. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(02)00028-0 · Cited by 635
Liposomes and skin: From drug delivery to model membranes
El Maghraby, G. M., Barry, B. W., & Williams, A. C. (2008) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2008.05.002 · Cited by 623
A Novel Phase Inversion-Based Process for the Preparation of Lipid Nanocarriers
Heurtault, B., Saulnier, P., Pech, B., Proust, J.-E., & Benoit, J.-P. (2002) · Pharmaceutical Research · doi:10.1023/a:1016121319668 · Cited by 583
Das, S., Ng, W. K., & Tan, R. B. H. (2012) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2012.05.010 · Cited by 576
Cited by
Priya, S., Desai, V. M., & Singhvi, G. (2023) · ACS Omega · doi:10.1021/acsomega.2c05976 · Cited by 228
Lipid nanoparticle-mediated drug delivery to the brain
Khare, P., Edgecomb, S. X., Hamadani, C. M., Tanner, E. E. L., & S Manickam, D. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114861 · Cited by 187
Bansal, K., Bhati, H., Vanshita, & Bajpai, M. (2024) · Pharmacological Research - Modern Chinese Medicine · doi:10.1016/j.prmcm.2024.100403 · Cited by 37
Vishwakarma, K. K., Hafeez, A., Usmani, S. A., Noor, L., & Khan, I. R. (2025) · Current Pharmaceutical Biotechnology · doi:10.2174/0113892010318524240907135527 · Cited by 4
Metadata
- Authors
- Chauhan, I., Yasir, M., Verma, M., & Singh, A. P.
- Venue
- Advanced Pharmaceutical Bulletin
- Publisher
- Maad Rayan Publishing Company
- Published
- 2020-02-18
- Volume
- 10
- Issue
- 2
- Pages
- 150-165
- ISSN
- 2228-5881 (ISSN-L)
- 2251-7308
- OpenAlex
- W3008004285
- Cited by
- 518
- References
- 59
- FWCI
- 17.97
- Type
- journal article
- Language
- en
- Open access
- diamond
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.