The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The Different Mechanisms of Cancer Drug Resistance: A Brief Review
Open accessAbstract
Anticancer drugs resistance is a complex process that arises from altering in the drug targets. Advances in the DNA microarray, proteomics technology and the development of targeted therapies provide the new strategies to overcome the drug resistance. Although a design of the new chemotherapy agents is growing quickly, effective chemotherapy agent has not been discovered against the advanced stage of cancer (such as invasion and metastasis). The cancer cell resistance against the anticancer agents can be due to many factors such as the individual's genetic differences, especially in tumoral somatic cells. Also, the cancer drug resistance is acquired, the drug resistance can be occurred by different mechanisms, including multi-drug resistance, cell death inhibiting (apoptosis suppression), altering in the drug metabolism, epigenetic and drug targets, enhancing DNA repair and gene amplification. In this review, we outlined the mechanisms of cancer drug resistance and in following, the treatment failures by common chemotherapy agents in the different type of cancers.
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Cites
Cancer drug resistance: an evolving paradigm
Holohan, C., Van Schaeybroeck, S., Longley, D. B., & Johnston, P. G. (2013) · Nature Reviews Cancer · doi:10.1038/nrc3599 · Cited by 4,681
Tumour stem cells and drug resistance
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Poised epigenetic states and acquired drug resistance in cancer
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Possible dominant-negative mutation of the SHIP gene in acute myeloid leukemia
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Cited by
Mechanisms of Multidrug Resistance in Cancer Chemotherapy
Bukowski, K., Kciuk, M., & Kontek, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093233 · Cited by 1,757
5-fluorouracil and other fluoropyrimidines in colorectal cancer: Past, present and future
Vodenkova, S., Buchler, T., Cervena, K., Veskrnova, V., Vodicka, P., & Vymetalkova, V. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.107447 · Cited by 956
Emran, T. B., Shahriar, A., Mahmud, A. R., Rahman, T., Abir, M. H., Siddiquee, M. F. R., Ahmed, H., Rahman, N., Nainu, F., Wahyudin, E., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.891652 · Cited by 606
The multi-factorial nature of clinical multidrug resistance in cancer
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Multidrug Resistance (MDR): A Widespread Phenomenon in Pharmacological Therapies
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Metadata
- Authors
- Mansoori, B., Mohammadi, A., Davudian, S., Shirjang, S., & Baradaran, B.
- Venue
- Advanced Pharmaceutical Bulletin
- Publisher
- Maad Rayan Publishing Company
- Published
- 2017-09-25
- Volume
- 7
- Issue
- 3
- Pages
- 339-348
- ISSN
- 2228-5881 (ISSN-L)
- 2251-7308
- OpenAlex
- W2769426045
- Cited by
- 1,883
- References
- 7
- FWCI
- 33.50
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Mansoori, B., Mohammadi, A., Davudian, S., Shirjang, S., & Baradaran, B. (2017). The Different Mechanisms of Cancer Drug Resistance: A Brief Review. Advanced Pharmaceutical Bulletin. https://doi.org/10.15171/apb.2017.041
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
