Cited by 270Antioxidant Activity and Oxidative StressRedox biology and oxidative stressExercise and Physiological Responses

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Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

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Ansarin, Khalil, Khoubnasabjafari, Maryam, Jouyban, Abolghasem·2017·BioImpacts

DOI 10.15171/bi.2015.20PMC PMC4597159

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Abstract

Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal that the reliability of MDA as a biomarker of oxidative stress n eeds to be re-evaluated by experts.

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Authors: Ansarin, K., Khoubnasabjafari, M., & Jouyban, A.
Affiliations: Tabriz University of Medical Sciences (IR)
Corresponding author: Jouyban, Abolghasem
ORCID: Ansarin, Khalil
Khoubnasabjafari, Maryam
Jouyban, Abolghasem
Venue: BioImpacts
Publisher: Maad Rayan Publishing Company
Published: 2017-08-23
Volume: 5
Issue: 3
Pages: 123-127
ISSN: 2228-5652 (ISSN-L)
2228-5660
DOI: 10.15171/bi.2015.20
PMC: PMC4597159
OpenAlex: W2281377718
Cited by: 270
References: 48
Citations by year: 2026: 13 · 2025: 22 · 2024: 26 · 2023: 32 · 2022: 41 · 2021: 29 · 2020: 45 · 2019: 19 · 2018: 28 · 2017: 10
FWCI: 9.85
Type: journal article
Language: en
Open access: diamond
doi.org
Licence: cc-by-nc
Locations: Bioimpacts (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
PubMed Central (publishedVersion, cc-by-nc)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Keywords: malondialdehyde, oxidative stress, biomarkers, mental illness, analytical reliability, lipid peroxidation, biomarker validity

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Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

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