Consumption of an Oral Carbohydrate-Protein Gel Improves Cycling Endurance and Prevents Postexercise Muscle Damage
Abstract
Investigators have reported improved endurance performance and attenuated post-exercise muscle damage with carbohydrate-protein beverages (CHO+P) versus carbohydrate-only beverages (CHO). However, these benefits have been demonstrated only when CHO+P was administered in beverage-form, and exclusively in male subjects. Thus, the purposes of this study were to determine if an oral CHO+P gel improved endurance performance and post-exercise muscle damage compared to a CHO gel, and determine if responses were similar between genders. Thirteen cyclists (8 men, 5 women; VO(2)peak = 57.9 +/- 7.0 ml x kg(-1) x min(-1)) completed two timed cycle-trials to volitional exhaustion at 75% of VO(2)peak. At 15-minute intervals throughout these rides, subjects received CHO or CHO+P gels, which were matched for carbohydrate content (CHO = 0.15 g CHO x kg BW(-1); CHO+P = 0.15 g CHO + 0.038 g protein x kg BW(-1)). Trials were performed using a randomly counterbalanced, double-blind design. Subjects rode 13% longer (p < 0.05) when utilizing the CHO+P gel (116.6 +/- 28.5 minutes) versus the CHO gel (102.8 +/- 25.0 minutes). In addition, men (101.8 +/- 24.6; 114.8 +/- 26.2) and women (104.4 +/- 28.6; 119.6 +/- 34.9) responded similarly to the CHO and CHO+P trials, with no significant treatment-by-gender effect. Postexercise creatine kinease (CK) was not significantly different between treatments. However, CK increased significantly following exercise in the CHO trial (183 +/- 116; 267 +/- 214 U x L(-1)), but not the CHO+P trial (180 +/- 133; 222 +/- 141 U x L(-1)). Therefore, to prolong endurance performance and prevent increases in muscle damage, it is recommended that male and female cyclists consume CHO+P gels rather than CHO gels during and immediately following exercise.
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Ingesting a light carbohydrate and protein snack 30 to 60 min prior to exercise also serves to increase availability of amino acids, decrease exercise-induced catabolism of protein, and minimize muscle damage.
“This also serves to increase availability of amino acids, decrease exercise-induced catabolism of protein, and minimize muscle damage [120–122].”
From ISSN exercise & sports nutrition review update: research & recommendations (2018) · cites this paper as [121]
Adding protein to a carbohydrate beverage/gel during exhaustive endurance exercise suppresses markers of muscle damage (creatine kinase) 12 to 24 h post-exercise.
“the scientific literature is consistent in reporting that adding protein to a carbohydrate beverage/gel during exhaustive endurance exercise suppresses markers of muscle damage (creatine kinase) 12 to 24 h post-exercise [8, 11–13]”
From International Society of Sports Nutrition Position Stand: protein and exercise (2017) · cites this paper as [12]
The addition of protein facilitates repair and recovery of the exercised muscle.
“the addition of protein facilitates repair and recovery of the exercised muscle [12].”
From International Society of Sports Nutrition Position Stand: protein and exercise (2017) · cites this paper as [12]
Pre-exercise administration of carbohydrate + protein combinations can favorably impact endurance performance.
“While none of these studies directly examined a timing comparison, they all demonstrate that pre-exercise administration of carbohydrate + protein combinations can favorably impact endurance performance.”
From International society of sports nutrition position stand: nutrient timing (2017) · cites this paper as [79]
Ingestion of a carbohydrate (0.146 g/kg) + protein (0.0365 g/kg) combination throughout an exhaustive bout of cycling exercise significantly improved cycling performance.
“The same research group [79] used a nutrient gel and again reported that ingestion of a carbohydrate (0.146 g/kg) + protein (0.0365 g/kg) combination throughout an exhaustive bout of cycling exercise significantly improved cycling performance.”
From International society of sports nutrition position stand: nutrient timing (2017) · cites this paper as [79]
Enhancements in endurance performance, as well as improved recovery of reduced muscle glycogen, have been consistently reported when carbohydrate + protein combinations have been consumed surrounding exercise bouts, particularly if lower quantities of carbohydrate are consumed.
“Towards this end, enhancements in endurance performance, as well as improved recovery of reduced muscle glycogen have also been consistently reported when carbohydrate + protein combinations have been consumed surrounding exercise bouts, particularly if lower quantities of carbohydrate are consumed.”
From International society of sports nutrition position stand: nutrient timing (2017) · cites this paper as [79]
Ingestion of carbohydrate + protein (or amino acids) in close temporal proximity to or throughout both endurance and resistance exercise may operate as an effective strategy to favorably affect performance of a subsequent exercise bout as well as adaptations from regular bouts of training.
“In summary, ingestion of carbohydrate + protein (or amino acids) in close temporal proximity to or throughout both endurance and resistance exercise may operate as an effective strategy to favorably affect performance of a subsequent exercise bout as well as adaptations from regular bouts of training.”
From International society of sports nutrition position stand: nutrient timing (2017) · cites this paper as [79]
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Cited by 149
- Authors
- Saunders, M. J., Luden, N. D., & Herrick, J. E.
- Affiliations
- James Madison University (US)
- Venue
- The Journal of Strength and Conditioning Research
- Published
- 2007
- Volume
- 21
- Issue
- 3
- Pages
- 678
- ISSN
- 1064-8011 (ISSN-L)
- 1533-4287
- OpenAlex
- W2013215090
- Cited by
- 149
- References
- 0
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 12 · 2023: 7 · 2022: 8 · 2021: 4 · 2020: 10 · 2019: 2 · 2018: 7 · 2017: 5 · 2016: 9 · 2015: 4 · 2014: 8 · 2013: 14 · 2012: 9
- FWCI
- 4.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Strength and Conditioning Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- endurance performance, creatine kinase, cycling, carbohydrate supplementation, protein supplementation, sex differences, cyclists, volitional exhaustion
- MeSH terms
- Administration, Oral, Adult, Analysis of Variance, Bicycling, Creatine Kinase, Dietary Carbohydrates, Dietary Proteins, Double-Blind Method, Female, Gels, Humans, Male, Physical Endurance, Muscle, Skeletal, Dietary Supplements
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