Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

Memory - A century of consolidation

McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250

Controlling the false discovery rate in behavior genetics research

Benjamini, Y., Drai, D., Elmer, G., Kafkafi, N., & Golani, I. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00297-2 · Cited by 4,146

The molecular biology of memory storage: a dialogue between genes and synapses

Kandel, E. R. (2001) · Science · doi:10.1126/science.1067020 · Cited by 3,917

Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders

Epstein, F. H., Lipton, S. A., & Rosenberg, P. A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199403033300907 · Cited by 2,676

Parallel human genome analysis: microarray-based expression monitoring of 1000 genes.

Schena, M., Shalon, D., Heller, R. A., Chai, A., Brown, P. O., & Davis, R. W. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.10614 · Cited by 1,599

Inflammation in Neurodegenerative Disease—A Double-Edged Sword

Wyss-Coray, T., & Mucke, L. (2002) · Neuron · doi:10.1016/s0896-6273(02)00794-8 · Cited by 1,235

Gene-expression profile of the ageing brain in mice

Lee, C.-K., Weindruch, R., & Prolla, T. A. (2000) · Nature Genetics · doi:10.1038/77046 · Cited by 1,055

Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory

Guzowski, J. F., Lyford, G. L., Stevenson, G. D., Houston, F. P., McGaugh, J. L., Worley, P. F., & Barnes, C. A. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-11-03993.2000 · Cited by 992

Molecular Characterization of Schizophrenia Viewed by Microarray Analysis of Gene Expression in Prefrontal Cortex

Mirnics, K., Middleton, F. A., Marquez, A., Lewis, D. A., & Levitt, P. (2000) · Neuron · doi:10.1016/s0896-6273(00)00085-4 · Cited by 882

Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites.

Steward, O., Wallace, C. S., Lyford, G., & Worley, P. (1998) · Neuron · doi:10.1016/s0896-6273(00)80591-7 · Cited by 845

Low Cerebrospinal Fluid Levels of Hemopexin Are Associated With Increased Alzheimer's Pathology, Hippocampal Hypometabolism, and Cognitive Decline

Ashraf, A., Dani, M., & So, P. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.590979 · Cited by 16

Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging

Paban, V., Billard, J., Bouët, V., Fréret, T., Boulouard, M., Chambon, C., Loriod, B., & Alescio‐Lautier, B. (2012) · Brain Structure and Function · doi:10.1007/s00429-012-0472-8 · Cited by 16

Synergy effects of HbA1c and variants of APOE and BDNFVal66Met explains individual differences in memory performance

Persson, N., Lavebratt, C., & Wåhlin, Å. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.08.017 · Cited by 15

A novel mouse model of the aged brain: Over-expression of the L-type voltage-gated calcium channel Ca V 1.3

Krueger, J. N., Moore, S. J., Parent, R., McKinney, B. C., Lee, A., & Murphy, G. G. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.06.054 · Cited by 15

Age- and Nicotine-Associated Gene Expression Changes in the Hippocampus of APP/PS1 Mice

Yang, J., Long, Y., Xu, D., Zhu, B., Deng, X., Yan, Z., Sun, F., & Chen, G.-J. (2019) · Journal of Molecular Neuroscience · doi:10.1007/s12031-019-01389-7 · Cited by 15

Phospho-Tau and Chromatin Landscapes in Early and Late Alzheimer’s Disease

Gil, L., Niño, S. A., Guerrero, C., & Jiménez-Capdeville, M. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910283 · Cited by 16

Expression Profile Analysis of Brain Aging

Ginsberg, S. D. (2007) · CRC Press eBooks · doi:10.1201/9781420005523-7 · Cited by 15

Genetic and pharmacological inactivation of adenosine A2Areceptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatum

Yu, L., Haverty, P. M., Mariani, J., Wang, Y., Shen, H., Schwarzschild, M. A., Weng, Z., & Chen, J. (2005) · Physiological Genomics · doi:10.1152/physiolgenomics.00068.2005 · Cited by 15

Neural system-enriched gene expression: relationship to biological pathways and neurological diseases

Zhang, J., Moseley, A. E., Jegga, A. G., Gupta, A., Witte, D. P., Sartor, M. A., Medvedovic, M., Williams, S. S., Ebert, C., Coolen, L. M., et al. (2004) · Physiological Genomics · doi:10.1152/physiolgenomics.00220.2003 · Cited by 15

Aging, Neuroinflammation, and Behavior

Johnson, R. W., & Godbout, J. P. (2007) · Elsevier eBooks · doi:10.1016/b978-012088576-3/50022-8 · Cited by 15

Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy

Horvath, S., Lacunza, E., Canatelli-Mallat, M., Portiansky, E. L., Gallardo, M. D., Brooke, R. T., Chiavellini, P., Pasquini, D. C., Girard, M., Lehmann, M., et al. (2024) · GeroScience · doi:10.1007/s11357-024-01269-y · Cited by 14

Survey of the Arc Epigenetic Landscape in Normal Cognitive Aging

Myrum, C., Kittleson, J. T., De, S., Fletcher, B. R., Castellano, J. F., Kundu, G., Becker, K. G., & Rapp, P. R. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-01915-4 · Cited by 14

Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide

Crivello, N. A., Rosenberg, I. H., Shukitt‐Hale, B., Bielinski, D. F., Dallal, G. E., & Joseph, J. A. (2007) · AGE · doi:10.1007/s11357-007-9039-7 · Cited by 14

Across sex and age: Learning and memory and patterns of avian hippocampal gene expression.

Kosarussavadi, S., Pennington, Z. T., Covell, J. J., Blaisdell, A. P., & Schlinger, B. A. (2017) · Behavioral Neuroscience · doi:10.1037/bne0000222 · Cited by 15

Aging-Related Calcium Dysregulation in Rat Entorhinal Neurons Homologous with the Human Entorhinal Neurons in which Alzheimer’s Disease Neurofibrillary Tangles First Appear

Gant, J. C., Kadish, I., Chen, K.-C., Thibault, O., Blalock, E. M., Porter, N. M., & Landfield, P. W. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180618 · Cited by 14

Tests for differential gene expression using weights in oligonucleotide microarray experiments

Hu, P., Beyene, J., & Greenwood, C. M. T. (2006) · BMC Genomics · doi:10.1186/1471-2164-7-33 · Cited by 14

Age at Onset: An Essential Variable for the Definition of Genetic Risk Factors for Sporadic Alzheimer's Disease

Beyer, K., Lao, J. I., Latorre, P., & Ariza, A. (2005) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2005.tb06138.x · Cited by 14

Amyloid Precursor Protein: From Synaptic Plasticity to Alzheimer's Disease

Mileusnić, R., Lancashire, C. L., & Rose, S. P. R. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1342.014 · Cited by 14

Xanthine-induced deficits in hippocampal behavior and abnormal expression of hemoglobin genes

Kambe, J., Miyata, S., Li, C., Yamamoto, Y., & Nagaoka, K. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114476 · Cited by 13

Neuroinflammation and oxidative injury in developmental neurotoxicity

Milatović, D., Zaja‐Milatovic, S., BREYER, R. M., Aschner, M., & Montine, T. J. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-382032-7.10064-5 · Cited by 13

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Kong, W., Mou, X., Xing, Z., Zhang, X., & Yang, Y. (2014) · Computational and Mathematical Methods in Medicine · doi:10.1155/2014/891761 · Cited by 13

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Pramanik, D., Mukherjee, S., & Dey, S. G. (2013) · Inorganic Chemistry · doi:10.1021/ic401771j · Cited by 13

LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease

Schrötter, A., Oberhaus, A., Kolbe, K., Seger, S., Mastalski, T., Magraoui, F. E., Hoffmann-Posorske, E., Bohnert, M., Deckert, J., Braun, C., et al. (2017) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2017.03.013 · Cited by 14

Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice

Britton, R., Liu, A. T., Rege, S. V., Adams, J. M., Akrapongpisak, L., Le, D., Alcantara‐Lee, R., Estrada, R. A., Ray, R. D., Ahadi, S., et al. (2022) · Brain and Behavior · doi:10.1002/brb3.2736 · Cited by 14

Age-related changes in the optic nerve of Sprague-Dawley rats: An ultrastructural and immunohistochemical study

Yassa, H. D. (2014) · Acta Histochemica · doi:10.1016/j.acthis.2014.05.001 · Cited by 12

Identification of significant features in DNA microarray data

Bair, E. (2013) · Wiley Interdisciplinary Reviews Computational Statistics · doi:10.1002/wics.1260 · Cited by 12

Untreated Hypertension Decreases Heritability of Cognition in Late Middle Age

Vasilopoulos, T., Kremen, W. S., Kim, K., Panizzon, M. S., Stein, P. K., Xian, H., Grant, M. D., Lyons, M. J., Toomey, R., Eaves, L. J., et al. (2011) · Behavior Genetics · doi:10.1007/s10519-011-9479-9 · Cited by 13

Accelerated midlife endocrine and bioenergetic brain aging in APOE4 females

Wang, T., Mao, Z., Shang, Y., Merlini, S., Vitali, F., Wiegand, J. L., & Brinton, R. D. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1632877 · Cited by 12

Structural aspects of the aging invertebrate brain

Koch, S. C., Nelson, A., & Hartenstein, V. (2021) · Cell and Tissue Research · doi:10.1007/s00441-020-03314-6 · Cited by 12

Glial glucocorticoid receptors in aged Fisher 344 (F344) and F344/Brown Norway rats

Kasckow, J. W., Xiao, C. Y., & Herman, J. P. (2009) · Experimental Gerontology · doi:10.1016/j.exger.2009.02.003 · Cited by 11

Dietary restriction lowers endogenous levels of oxidative stress in different brain regions of adult mice.

Rathod, P., Hemnani, T., & Parihar, M. S. (2011) · PubMed · Cited by 11

CART variance stabilization and regularization for high-throughput genomic data

Papana, A., & Ishwaran, H. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl384 · Cited by 11

Cellular and Molecular Mechanisms for Age-Related Cognitive Decline

Barter, J., & Foster, T. C. (2019) · Cambridge University Press eBooks · doi:10.1017/9781108554350.003 · Cited by 11

Non-canonical hemoglobin: An updated review on its ubiquitous expression

Reed, E. C., Kim, J. D., & Case, A. J. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103602 · Cited by 10

Effect of ladostigil treatment of aging rats on gene expression in four brain areas associated with regulation of memory

Linial, M., Stern, A., & Weinstock, M. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108229 · Cited by 10

Gene expression profile in rat hippocampus with and without memory deficit

Paban, V., Farioli, F., Romier, B., Chambon, C., & Alescio‐Lautier, B. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.03.005 · Cited by 11

New cellular and molecular approaches to ageing brain

Tripathi, A. (2012) · Annals of Neurosciences · doi:10.5214/ans.0972.7531.190410 · Cited by 11

Neuroendocrinology of Aging

Brinton, R. D. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-6231-8.10027-3 · Cited by 10

Behavioral and Cellular Tagging in Young and in Early Cognitive Aging

Gros, A., Lim, A. W. H., Hohendorf, V., White, N. C., Eckert, M. J., McHugh, T. J., & Wang, S. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.809879 · Cited by 11

Reproductive Aging of Females: Neural Systems

Brinton, R. D., Gore, A. C., Schmidt, P. J., & Morrison, J. H. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00068-1 · Cited by 10

Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis

Kai, N., Iwase, K., Imai, K., Nakahira, E., Soma, M., Ohtsuka, S., Yagi, T., Kobayashi, K., Koga, H., Takiguchi, M., et al. (2006) · Brain Research · doi:10.1016/j.brainres.2005.12.042 · Cited by 10

Gene Network Construction from Microarray Data Identifies a Key Network Module and Several Candidate Hub Genes in Age-Associated Spatial Learning Impairment

Uddin, R., & Singh, S. M. (2017) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2017.00075 · Cited by 9

Neuroadaptive Trajectories of Healthy Mindspan: From Genes to Neural Networks

Rapp, P. R., Bañuelos, C., & Myrum, C. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108552684.005 · Cited by 9

The Application of Microarray Technology to Neuropathology: Cutting Edge Tool With Clinical Diagnostics Potential or Too Much Information?

McShea, A., Marlatt, M. W., Lee, H., Tarkowsky, S. M., Smit, M., & Smith, M. A. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/01.jnen.0000240471.04920.3c · Cited by 9

Oligonucleotide-based Analysis of Differentially Expressed Genes in Hippocampus of Transgenic Mice Expressing NSE-controlled APPsw

Jee, S. W., Cho, J. S., Kim, C. K., Hwang, D. Y., Shim, S. B., Lee, S. H., Sin, J. S., Park, J. H., Kim, Y. S., Choi, S. Y., et al. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9117-8 · Cited by 9

Acute psychosocial stress in mid-aged male rats causes hyperthermia, cognitive decline, and increased deep sleep power, but does not alter deep sleep duration

Hargis, K., Buechel, H. M., Popović, J., & Blalock, E. M. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.06.009 · Cited by 9

Hepatic Genes Altered in Expression by Food Restriction Are Not Influenced by the Low Plasma Glucose Level in Young Male GLUT4 Transgenic Mice

Fu, C., Liang, X., Wu, Y., McCarter, R., Richardson, A. G., Hickey, M., & Han, E.-S. (2004) · Journal of Nutrition · doi:10.1093/jn/134.11.2965 · Cited by 9

Fluoxetine Ameliorates Cognitive Deficits in High-Fat Diet Mice by Regulating BDNF Expression

Zuo, X., Zhu, Z., Liu, M., Zhao, Q., Li, X., Zhao, X., & Feng, X. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00540 · Cited by 9

Chronological Pattern Exploration Algorithm for Gene Expression Data Clustering and Classification

Sharmila, L., & Sakthi, U. (2017) · Wireless Personal Communications · doi:10.1007/s11277-017-5208-x · Cited by 8

Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex

Martinović, J., Kontić, M. Z., Dragić, M., Todorović, A., Stojanović, I. G., Mitrović, N., Grković, I., & Drakulić, D. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114072 · Cited by 8

Age-changes in gene expression in primary mixed glia cultures from young vs. old rat cerebral cortex are modified by interactions with neurons

Kremsky, I., Morgan, T. E., Hou, X., Li, L., & Finch, C. E. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.12.008 · Cited by 10

The effects of aging vs. α7 nAChR subunit deficiency on the mouse brain transcriptome: aging beats the deficiency

Kedmi, M., & Orr‐Urtreger, A. (2010) · AGE · doi:10.1007/s11357-010-9155-7 · Cited by 8

Recovery of Age-Related Memory Loss: Hopes and Challenges

Thakur, M. K., Konar, A., Kumar, D., Baghel, M. S., & Singh, P. (2016) · Springer eBooks · doi:10.1007/978-981-10-2155-8_14 · Cited by 8

Sex as a determinant of age-related changes in rat spinal cord inflammation-oxidation state

Nacka-Aleksić, M., Stojanović, M., Simic, L., Bufan, B., Kotur‐Stevuljević, J., Stojić-Vukanić, Z., Dimitrijević, M., Ražić, S., & Leposavić, G. (2017) · Biogerontology · doi:10.1007/s10522-017-9726-4 · Cited by 9

Application of DNA Microarray Technology to Gerontological Studies

Anisimov, S. V. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-361-5_19 · Cited by 8

Microarray analysis of aging-associated immune system alterations in the rostral ventrolateral medulla of F344 rats

Balivada, S., Ganta, C. K., Zhang, Y., Pawar, H. N., Ortiz, R. J., Becker, K. G., Khan, A. M., & Kenney, M. (2017) · Physiological Genomics · doi:10.1152/physiolgenomics.00131.2016 · Cited by 7

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Iqbal, J. (2018) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2018.82005 · Cited by 7

Neuroinflammation and oxidative injury in developmental neurotoxicity

Milatović, D., Zaja‐Milatovic, S., Brockett, M. M., BREYER, R. M., Aschner, M., & Montine, T. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89773-0.00056-4 · Cited by 7

Disease Modeling of Neurodegenerative Disorders Using Direct Neural Reprogramming

Legault, E. M., Bouquety, J., & Drouin‐Ouellet, J. (2022) · Cellular Reprogramming · doi:10.1089/cell.2021.0172 · Cited by 7

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Nott, A., Fass, D. M., Haggarty, S. J., & Tsai, L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-391494-1.00008-2 · Cited by 8

Transcriptomic changes in the prefrontal cortex of rats as a function of age and cognitive engagement

Duggan, M. R., Joshi, S., Tan, Y., Slifker, M. J., Ross, E. A., Wimmer, M. E., & Parikh, V. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.107035 · Cited by 7

Biological processes and key druggable targets involved in age-associated memory loss: A systematic review

Unni, P. A., Pillai, G. G., & Sajithalulu, S. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119079 · Cited by 7

Normal Neurocognitive Aging

Fletcher, B. R., & Rapp, P. R. (2012) · Wiley eBooks · doi:10.1002/9781118133880.hop203024 · Cited by 8

Human Reproductive Costs and the Predicted Response to Dietary Restriction

Arking, R. (2007) · Rejuvenation Research · doi:10.1089/rej.2007.0519 · Cited by 7

Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hippocampal Gene Expression

Vergnes, L., Phan, J., & Reue, K. (2004) · CRC Press eBooks · doi:10.1201/9781420030921-8 · Cited by 6

Molecular Biomarkers of Aging

Davinelli, S., Vasto, S., Caruso, C., Zella, D., & Scapagnini, G. (2012) · InTech eBooks · doi:10.5772/32944 · Cited by 6

Experience-dependent persistent Arc expression is reduced in the aged hippocampus

Gheidi, A., Damphousse, C. C., & Marrone, D. F. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.07.032 · Cited by 6

New Insight in The Molecular Mechanisms of Neurodegenerative Disease

Meiliana, A., Dewi, N. M., & Wijaya, A. (2018) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v10i1.448 · Cited by 6

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Fernández‐Ruíz, J., Sagredo, O., Gómez‐Ruíz, M., & de Lago, E. (2025) · Current topics in behavioral neurosciences · doi:10.1007/7854_2025_597 · Cited by 5

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Bilgic, M., Obata, R., Panfil, V., Zhu, Z., Saeki, M., Gotoh, Y., & Kishi, Y. (2025) · Aging Cell · doi:10.1111/acel.70233 · Cited by 5

Integrative Transcriptome Profiling of Cognitive Aging and Its Preservation through Ser/Thr Protein Phosphatase Regulation

Park, C. S., Valomon, A., & Welzl, H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0130891 · Cited by 5

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Unno, K., Yamamoto, H., Ohtaki, T., Ishikawa, Y., Noda, S., Maeda, K., Fujitani, K., Miyazaki, H., Takabayashi, F., Sasaki, T., et al. (2011) · Anti-aging Medicine · doi:10.3793/jaam.8.75 · Cited by 5

In vivo and ex vivo analyses of amyloid toxicity in the Tc1 mouse model of Down syndrome

Naert, G., Ferré, V. M., Keller, E., Slender, A., Gibbins, D., Fisher, E., Tybulewicz, V. L. J., & Maurice, T. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881117743484 · Cited by 5

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Emanetci, E., & Çakır, T. (2021) · Journal of Molecular Neuroscience · doi:10.1007/s12031-021-01807-9 · Cited by 5

Microarray Analysis of Gene Expression Changes in Aging

Hudson, F. N., Kaeberlein, M. R., Linford, N. J., Pritchard, D. K., Beyer, R., & Rabinovitch, P. S. (2005) · Elsevier eBooks · doi:10.1016/b978-012088387-5/50014-5 · Cited by 4

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Douillard‐Guilloux, G., Guilloux, J., Lewis, D. A., & Sibille, E. L. (2012) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e318266b7ad · Cited by 4

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Srivas, S., & Thakur, M. K. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.11398-4 · Cited by 3

Study DNA Microarray Gene Expression Data of Alzheimer's Disease by Independent Component Analysis

Kong, W., Mou, X., & Yang, B. (2009) · International Joint Conferences on Bioinformatics, Systems Biology and Intelligent Computing · doi:10.1109/ijcbs.2009.106 · Cited by 3

Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance

Mei, H., Simino, J. M., Li, L., Jiang, F., Bis, J. C., Davies, G., Hill, W. D., Xia, C., Gudnason, V. G., Yang, Q., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01376-6 · Cited by 3

Effect of growth hormone and melatonin on the brain: from molecular mechanisms to structural changes

Kireev, R. A., Cuesta‐Sancho, S., Vara, E., & Tresguerres, J. A. F. (2011) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci.2011.115 · Cited by 3

Fish Oil Supplementation Prevents Age-Related Memory Decline

Alfos, S. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-410527-0.00013-2 · Cited by 3

Identification of Potential Key lncRNAs and Genes Associated with Aging Based on Microarray Data of Adipocytes from Mice

Yang, Y., Teng, Z., Meng, S., & Yu, W. (2016) · BioMed Research International · doi:10.1155/2016/9181702 · Cited by 3

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Booker, S. A. (2020) · Journal of Visualized Experiments · doi:10.3791/61699 · Cited by 3

9 Genome-wide Views of Aging Gene NetworksPreprint

Kim, S. K. (2008) · Cold Spring Harbor Monograph Archive · doi:10.1101/087969824.51.215 · Cited by 3

The Ageless Question--What Accounts for Age-Related Cognitive Decline?

Nagahara, A. H., & Tuszynski, M. H. (2004) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2004.19.pe20 · Cited by 3

Roles of Innate Immunity and Inflammation in the Aging Brain

Okun, E., Chen, X., Bašta, M., & Mattson, M. P. (2011) · Oxidative stress and disease · doi:10.1201/b11014-2 · Cited by 2

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Shukla, R., Oh, H., & Sibille, E. L. (2019) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2019.06.001 · Cited by 2

Classical Models of Senile Osteoporosis

Watanabe, K. (2011) · Springer eBooks · doi:10.1007/978-0-85729-293-3_10 · Cited by 2

DNA Microarrays and Animal Models of Learning and Memory

Cavallaro, S. (2004) · International review of neurobiology · doi:10.1016/s0074-7742(04)60004-3 · Cited by 2

Gene-specific oxidative lesions in aged rat brain detected by polymerase chain reaction inhibition assay

Sen, T., Jana, S., Sreetama, S. C., Chatterjee, U., & Chakrabarti, S. (2006) · Free Radical Research · doi:10.1080/10715760601083722 · Cited by 2

Neurological Effects of Dietary n-3 Fatty Acids in Rat Brain

Barceló‐Coblijn, G., Farkas, T., Pusk√°s, L., & Kitajka, K. (2004) · CRC Press eBooks · doi:10.1201/9781420030921.ch5 · Cited by 2

A modified F-test for hypothesis testing in large-scale data

Salehi, M., Mohammadpour, A., Mohammadi, M., & Aminghafari, M. (2018) · Journal of Biopharmaceutical Statistics · doi:10.1080/10543406.2018.1436557 · Cited by 2

The Interest of Adding Micronutrients to Docosahexaenoic Acid Supplementation to Prevent Age-Related Cognitive Decline

Chataigner, M., Dinel, A., Pallet, V., Layé, S., & Joffre, C. (2018) · Journal of Alzheimer’s Disease & Parkinsonism · doi:10.4172/2161-0460.1000438 · Cited by 2

The Principal Inferior Olivary Nucleus in Aging and Alzheimer's Disease

Lasn, H. (2006) · Figshare · Cited by 2

Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hippocampal Gene Expression

Roberts, M., & Berger, A. (2004) · CRC Press eBooks · doi:10.1201/9781420030921.ch3 · Cited by 2

Psilocybin reduces depressive-like behavior and improves cognition in healthy aging mice via epigenetic regulation of plasticity- and immune-related genesPreprint

Mennenga, S. E., Hanson, T., Semple, M. G., Lifshitz, D., Flores, B., Balducci, J., Harker, S. A., Ford, A., & Lewis, C. R. (2025) · Research Square · doi:10.21203/rs.3.rs-7890051/v1 · Cited by 2

Aging and the Hippocampus

Burke, S. N., & Barnes, C. A. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780190065324.003.0015 · Cited by 1

Light-evoked activity and BDNF regulate mitochondrial dynamics and mitochondrial localized translation in CNS axons

Kreymerman, A., Weinstein, J. E., Vadgama, N., Shah, S. H., Nahmou, M. M., Belle, K. C., Ji, M. H., Xia, X., Faust, A. E., van der Merwe, Y., et al. (2025) · iScience · doi:10.1016/j.isci.2025.113563 · Cited by 1

Individual Differences in Cognitive Aging Rodent Datasets (ID-CARD): A collaborative platform for behavioral analysis across the lifespan

McQuail, J. A., Barnes, C. A., Bizon, J. L., Burke, S. N., Disterhoft, J. F., Foster, T. C., Huentelman, M. J., Kaczorowski, C. C., Long, J. M., Moore, S. J., et al. (2026) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2026.09.003 · Cited by 1

Learning the local molecular pattern of Alzheimer's disease by non-negative matrix factorization

Kong, W., Mou, X., Li, Q., & Song, Y. (2010) · International Conference on Green Circuits and Systems · doi:10.1109/icgcs.2010.5542987 · Cited by 1

Hippocampal transcriptome profiling in the aged rat brain for the prediction of age-associated cognitive decline

Damanhuri, H. A., Aliah, A. N., Makpol, S., Musalmah, M., & Zurinah, W. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/conf.fncel.2016.36.00030

Hippocampal Expression Analyses Reveal Selective Association of Immediate-Early, Neuroenergetic, and Myelinogenic Pathways with Cognitive Impairment in Aged Rats

Rowe, W. B., Blalock, E. M., Chen, K.-C., Kadish, I., Wang, D., Barrett, J. E., Thibault, O., Porter, N. M., Rose, G. M., & Landfield, P. W. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4163-06.2007 · Cited by 215

DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain

Mi-Suk, L., Heo, J., Kim, J., Park, J., Lee, J.-Y., Han, J.-A., & Jong-Il, K. (2006) · Seoul National University Open Repository (Seoul National University)

Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: Statistical reliability and functional correlation

Blalock, E. M., Chen, K.-C., Stromberg, A. J., Norris, C. M., Kadish, I., Kraner, S. D., Porter, N. M., & Landfield, P. W. (2005) · Ageing Research Reviews · doi:10.1016/j.arr.2005.06.006 · Cited by 102

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

Cribbs, D. H., Berchtold, N. C., Perreau, V., Coleman, P. D., Rogers, J., Tenner, A. J., & Cotman, C. W. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-179 · Cited by 499