Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization

Diagnostic and Statistical Manual of Mental Disorders

Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845

“Mini-mental state”

Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282

Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., & Selkoe, D. J. (2002) · Nature · doi:10.1038/416535a · Cited by 4,291

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., et al. (1999) · Nature · doi:10.1038/22124 · Cited by 3,160

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Bard, F., Cannon, C., Barbour, R., Burke, R.-L., Games, D., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., et al. (2000) · Nature Medicine · doi:10.1038/78682 · Cited by 2,012

Natural oligomers of the amyloid-β protein specifically disrupt cognitive function

Cleary, J. P., Walsh, D. M., Hofmeister, J. J., Shankar, G. M., Kuskowski, M. A., Selkoe, D. J., & Ashe, K. H. (2004) · Nature Neuroscience · doi:10.1038/nn1372 · Cited by 1,722

Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

Hansson, O., Zetterberg, H., Buchhave, P., Londos, E., Blennow, K., & Minthon, L. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70355-6 · Cited by 1,700

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

Janus, C., Pearson, J., McLaurin, J., Mathews, P. M., Jiang, Y., Schmidt, S. D., Chishti, M. A., Horne, P., Heslin, D., French, J., et al. (2000) · Nature · doi:10.1038/35050110 · Cited by 1,431

A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF

Bigi, A., Napolitano, L., Vadukul, D. M., Chiti, F., Cecchi, C., Aprile, F. A., & Cascella, R. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01361-z · Cited by 23

Targeting soluble amyloid-beta oligomers with a novel nanobody

Haynes, J. R., Whitmore, C. A., Behof, W. J., Landman, C. A., Ong, H. H., Feld, A. P., Suero, I. C., Greer, C. B., Gore, J. C., Wijesinghe, P., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-66970-6 · Cited by 23

Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease

Ahnaou, A., Walsh, C., Manyakov, N. V., Youssef, S. A., & Drinkenburg, W. H. I. M. (2019) · Neural Plasticity · doi:10.1155/2019/6981268 · Cited by 24

Functional Selectivity of Dopamine D1 Receptor Signaling: Retrospect and Prospect

Yang, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111914 · Cited by 23

cAMP-Inhibits Cytoplasmic Phospholipase A2 and Protects Neurons against Amyloid-β-Induced Synapse Damage

Bate, C., & Williams, A. (2015) · Biology · doi:10.3390/biology4030591 · Cited by 22

Cytoplasmic expression of mouse prion protein causes severe toxicity in Caenorhabditis elegans

Park, K.-W., & Li, L. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.05.132 · Cited by 21

A Human Monoclonal IgG That Binds Aβ Assemblies and Diverse Amyloids Exhibits Anti-Amyloid ActivitiesIn VitroandIn Vivo

Levites, Y., O’Nuallain, B., Puligedda, R. D., Ondrejčák, T., Adekar, S. P., Chen, C. S., Cruz, P. E., Rosario, A. M., Macy, S. D., Mably, A. J., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.5109-14.2015 · Cited by 21

Inherent Anti-amyloidogenic Activity of Human Immunoglobulin γ Heavy Chains

Adekar, S. P., Klyubin, I. V., Macy, S., Rowan, M. J., Solomon, A., Dessain, S. K., & O’Nuallain, B. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.044321 · Cited by 21

The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer’s Disease

Busch, L., Eggert, S., Endres, K., & Bufe, B. (2022) · Cells · doi:10.3390/cells11213421 · Cited by 20

Exploring Amyloid-β Dimer Structure Using Molecular Dynamics Simulations

Mehrazma, B., & Rauk, A. (2019) · The Journal of Physical Chemistry A · doi:10.1021/acs.jpca.8b11251 · Cited by 20

Tau tubulin kinases in proteinopathy

Taylor, L. M., McMillan, P. J., Kraemer, B. C., & Liachko, N. F. (2019) · FEBS Journal · doi:10.1111/febs.14866 · Cited by 20

Copper(ii) and zinc(ii) dependent effects on Aβ42 aggregation: a CD, Th-T and SFM study

Attanasio, F., Bona, P. D., Cataldo, S., Sciacca, M. F. M., Milardi, D., Pignataro, B., & Pappalardo, G. (2013) · New Journal of Chemistry · doi:10.1039/c3nj40999f · Cited by 20

Two Distinct Conformations of Aβ Aggregates on the Surface of Living PC12 Cells

Bateman, D. A., & Chakrabartty, A. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2009.01.056 · Cited by 19

Different effects of soluble and aggregated amyloid β42 on gene/protein expression and enzyme activity involved in insulin and APP pathways

Bartl, J., Meyer, A. H., Brendler, S., Riederer, P., & Grünblatt, E. (2012) · Journal of Neural Transmission · doi:10.1007/s00702-012-0852-5 · Cited by 19

Synthesis and biochemical characterization of quasi-stable trimer models of full-length amyloid β40 with a toxic conformation

Irie, Y., Hanaki, M., Murakami, K., Imamoto, T., Furuta, T., Kawabata, T., Kawase, T., Hirose, K., Monobe, Y., Akagi, K., et al. (2018) · Chemical Communications · doi:10.1039/c8cc08618d · Cited by 19

PIP2: a new key player in Alzheimer's disease.

Arancio, O. (2008) · PubMed · Cited by 18

Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity

Scopes, D., O‘Hare, E., Jeggo, R., Whyment, A. D., Spanswick, D. C., Kim, E.-M., Gannon, J., Amijee, H., & Treherne, J. M. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.01973.x · Cited by 17

Alleviating the unwanted effects of oxidative stress on Aβ clearance: a review of related concepts and strategies for the development of computational modelling

Somin, S., Kulasiri, D., & Samarasinghe, S. (2023) · Translational Neurodegeneration · doi:10.1186/s40035-023-00344-2 · Cited by 18

RS-0406 Arrests Amyloid-β Oligomer-Induced Behavioural Deterioration In Vivo

O‘Hare, E., Scopes, D. I. C., Treherne, J. M., Norwood, K., Spanswick, D. C., & Kim, E. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.01.044 · Cited by 17

Computational identification of potential multitarget treatments for ameliorating the adverse effects of amyloid-β on synaptic plasticity

Anastasio, T. J. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00085 · Cited by 17

P3‐292: Grape seed polyphenolic extract specifically decreases Aβ∗56 in the brains of Tg2576 mice

Liu, P., Kotilinek, L., Kemper, L. J., Wang, J., Zahs, K. R., Ashe, K. H., & Pasinetti, G. M. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2010.05.1792 · Cited by 17

Biochemical Markers in Alzheimer's Disease Clinical Trials

Zetterberg, H., Mattsson, N., Shaw, L. M., & Blennow, K. (2010) · Biomarkers in Medicine · doi:10.2217/bmm.09.80 · Cited by 17

Direct Correlation of Cell Toxicity to Conformational Ensembles of Genetic Aβ Variants

Somavarapu, A. K., & Kepp, K. P. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00238 · Cited by 15

Synthesis and SAR of hydroxyethylamine based phenylcarboxyamides as inhibitors of BACE.

Wu, Y.-J., Zhang, Y.-H., Good, A., Burton, C., Toyn, J., Albright, C., Macor, J., & Thompson, L. (2009) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2009.03.144 · Cited by 14

Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease

O‘Hare, E., Scopes, D. I. C., Kim, E., Palmer, P., Spanswick, D. C., McMahon, B., Amijee, H., Nerou, E., Treherne, J. M., & Jeggo, R. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000886 · Cited by 16

A Window into the Heterogeneity of Human Cerebrospinal Fluid Aβ Peptides

Ghidoni, R., Paterlini, A., Albertini, V., Stoppani, E., Binetti, G. G., Fuxé, K., Benussi, L., & Agnati, L. F. (2011) · BioMed Research International · doi:10.1155/2011/697036 · Cited by 15

Synthetic, Cell-Derived, Brain-Derived, and Recombinant β-Amyloid: Modelling Alzheimer’s Disease for Research and Drug Development

Varshavskaya, K. B., Mitkevich, V. A., Makarov, A. А., & Barykin, E. P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315036 · Cited by 18

Combining intracellular selection with protein-fragment complementation to derive A interacting peptides

Acerra, N., Kad, N. M., & Mason, J. M. (2013) · Protein Engineering Design and Selection · doi:10.1093/protein/gzt021 · Cited by 15

Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis

Chiang, A. C. A., Fowler, S., Reddy, R., Pletniková, O., Troncoso, J. C., Sherman, M. A., Lesné, S., & Jankowsky, J. L. (2017) · American Journal Of Pathology · doi:10.1016/j.ajpath.2017.11.011 · Cited by 17

AD Vaccines: Conclusions and Future Directions

Wisniewski, T. (2009) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152709787847289 · Cited by 14

Emergence of Barrel Motif in Amyloid-β Trimer: A Computational Study

Nguyen, H. L., Linh, H. Q., Matteini, P., Penna, G. L., & Li, M. S. (2020) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.0c05508 · Cited by 15

IPSC-Derived Neuronal Cultures Carrying the Alzheimer’s Disease Associated TREM2 R47H Variant Enables the Construction of an Aβ-Induced Gene Regulatory Network

Martins, S., Müller‐Schiffmann, A., Erichsen, L., Bohndorf, M., Wruck, W., Sleegers, K., Broeckhoven, C. V., Korth, C., & Adjaye, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21124516 · Cited by 14

Immunotherapy for the treatment of Alzheimer's disease: amyloid-β or tau, which is the right target?

Kayed, R., Castillo‐Carranza, D. L., & Guerrero‐Munoz, M. J. (2013) · ImmunoTargets and Therapy · doi:10.2147/itt.s40131 · Cited by 16

A mimotope peptide of Aβ42 fibril-specific antibodies with Aβ42 fibrillation inhibitory activity induces anti-Aβ42 conformer antibody response by a displayed form on an M13 phage in mice

Tanaka, K., Nishimura, M., Yamaguchi, Y., Hashiguchi, S., Takiguchi, S., Yamaguchi, M., Tahara, H., Gotanda, T., Abe, R., Ito, Y., et al. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2011.04.010 · Cited by 14

Amyloid solutions: lecanemab, gantenerumab, and donanemab in the treatment of Alzheimer's disease

Ameen, T. B., Ali, U., Salma, O., Samee, M. A., Abbas, S. M. I., Kashif, S. N., Arifi, M. A., Ali, M., Khowaja, M., Ali, S. M. S., et al. (2025) · The Egyptian Journal of Neurology Psychiatry and Neurosurgery · doi:10.1186/s41983-025-00968-3 · Cited by 20

Aβ dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease

Abdel‐Hafiz, L., Müller‐Schiffmann, A., Korth, C., Fazari, B., Chao, O. Y.-H., Nikolaus, S., Schäble, S., Herring, A., Keyvani, K., Lamounier‐Zepter, V., et al. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2018.04.005 · Cited by 13

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

Mengel, D., Mok, T. H., Nihat, A., Liu, W., Rissman, R. A., Galasko, D., Zetterberg, H., Mead, S., Collinge, J., & Walsh, D. M. (2021) · Cells · doi:10.3390/cells10123514 · Cited by 12

A Disulfide-Stabilized Aβ that Forms Dimers but Does Not Form Fibrils

Zhang, S., Yoo, S., Snyder, D. T., Katz, B. B., Henrickson, A., Demeler, B., Wysocki, V. H., Kreutzer, A. G., & Nowick, J. S. (2022) · Biochemistry · doi:10.1021/acs.biochem.1c00739 · Cited by 12

The preventive effect of NR2B and NR2D-containing NMDAR antagonists on Aβ-induced LTP disruption in the dentate gyrus of rats

Zhang, J., Wang, C., Deng, T., Xue, Z., Chen, X., Chang, L. Y., & Wang, Q. (2013) · Metabolic Brain Disease · doi:10.1007/s11011-013-9424-0 · Cited by 12

Cerebrospinal Fluid from Alzheimer's Disease Patients Promotes Amyloid β-Protein Oligomerization

Ikeda, T., Ono, K., Elashoff, D. A., Condron, M. M., Noguchi‐Shinohara, M., Yoshita, M., Teplow, D. B., & Yamada, M. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100075 · Cited by 12

Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting

Sandoval, K. E., & WITT, K. A. (2024) · Pharmacological Reviews · doi:10.1124/pharmrev.124.001117 · Cited by 14

Inhibition of hippocampal mossy fiber plasticity and episodic memory by human Aβ oligomers is prevented by enhancing cAMP signaling in Alzheimer's mice

Jin, S., Bellier, J., Wells, A. R., Llopis, P. D. L. M. M., Anekal, P. V., Tresback, J. S., Caldarone, B. J., Liu, L., Li, S., Dettmer, U., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70194 · Cited by 11

Influence of amyloid beta on impulse spiking of isolated hippocampal neurons

Yavorsky, V. A., Rozumna, N. M., & Lukyanetz, E. A. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1132092 · Cited by 11

The Unexpected Capability of Melanin to Split the Water Molecule and the Alzheimer’s Disease

Arias-Esparza, M. D. C., Arias, R. I. S., Arias, P. E. S., Arias, M. P. S., & Solís-Herrera, A. (2011) · Neuroscience & Medicine · doi:10.4236/nm.2011.23029 · Cited by 10

Does Alzheimer's Disease Result from Attempts at Repair or Protection After Transient Stress?

Bissette, G. (2009) · Journal of Alzheimer s Disease · doi:10.3233/jad-2009-1171 · Cited by 11

Is Covalently Crosslinked Aβ Responsible for Synaptotoxicity in Alzheimers Disease?

Naylor, R., Hill, A. F., & Barnham, K. J. (2008) · Current Alzheimer Research · doi:10.2174/156720508786898433 · Cited by 10

Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-β oligomers released from 7PA2 cells

Williams, R. S. B., & Bate, C. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.09.031 · Cited by 10

Beta-amyloid oligomers: recent developments

Borutaite, V., Morkuniene, R., & Valincius, G. (2011) · bmc · doi:10.1515/bmc.2011.019 · Cited by 9

Constructing conformational library for amyloid-β42 dimers as the smallest toxic oligomers using two CHARMM force fields

Dehabadi, M. H., & Firouzi, R. (2022) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2022.108207 · Cited by 10

NGP 555, a γ‐secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses

Kounnas, M. Z., Durakoglugil, M. S., Herz, J., & Comer, W. T. (2019) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1016/j.trci.2019.06.006 · Cited by 9

Assessments of the Effect of Neurokinin B on Toxic Aβ Aggregates in Alzheimer’s Disease with the Molecular Mechanisms’ Action

Press‐Sandler, O., & Miller, Y. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00535 · Cited by 9

The Role of Aβ and Tau Oligomers in the Pathogenesis of Alzheimer’s Disease

Bhaskar, K., & Lamb, B. T. (2011) · Springer eBooks · doi:10.1007/978-94-007-2774-8_5 · Cited by 8

Oligomeropathies, inflammation and prion protein binding

Forloni, G., Vitola, P. L., & Balducci, C. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.822420 · Cited by 8

Probing the efficacy of peptide-based inhibitors against acid- and zinc-promoted oligomerization of amyloid-β peptide via single-oligomer spectroscopy

Powell, L. R., Dukes, K. D., & Lammi, R. K. (2011) · Biophysical Chemistry · doi:10.1016/j.bpc.2011.08.006 · Cited by 8

Characterization of behavioral changes in T-maze alternation from dopamine D1 agonists with different receptor coupling mechanisms

Cimino, J. X., Zhou, M., Waxmonsky, J. G., Mailman, R. B., & Yang, Y. (2023) · Psychopharmacology · doi:10.1007/s00213-023-06440-5 · Cited by 8

Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-β oligomers

McHale-Owen, H., & Bate, C. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.12.017 · Cited by 7

Screening of BACE1 inhibitors with antiamyloidogenic activity: A study of flavonoids and flavonoid derivatives

Das, S., Datta, S., Ghosal, A., Chaudhuri, N. R., Sundaram, G., & Basu, S. (2022) · Neuroscience Letters · doi:10.1016/j.neulet.2022.136965 · Cited by 7

Molecular Mechanisms in Synaptic Plasticity

Mayadevi, M., Archana, G. M., Ramya, R., & Omkumar, R. V. (2012) · InTech eBooks · doi:10.5772/36928 · Cited by 7

Aβ oligomer induced cognitive impairment and evaluation of ACU193‐MNS‐based MRI in rabbit

Rozema, N. B., Procissi, D., Bertolino, N., Viola, K. L., Nandwana, V., Abdul, N., Pribus, S. J., Dravid, V. P., Klein, W. L., Disterhoft, J. F., et al. (2020) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.12087 · Cited by 6

Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models

Uchino, A., Irie, Y., Tsukano, C., Kawase, T., Hirose, K., Kageyama, Y., Tooyama, I., Yanagita, R. C., & Irie, K. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00363 · Cited by 6

Redox reactivities of membrane-bound amyloid-β-Cu complexes and their targeting by metallothionein-3

Perez-Medina, L., & Meloni, G. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.08.047 · Cited by 5

Patterns of cognitive decline and somatosensory processing in a mouse model of amyloid accumulation

Uddin, O., Arakawa, K., Raver, C., Garagusi, B., & Keller, A. (2021) · Neurobiology of Pain · doi:10.1016/j.ynpai.2021.100076 · Cited by 6

Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-β oligomers

Nolan, W., McHale-Owen, H., & Bate, C. (2017) · Biochemical Journal · doi:10.1042/bcj20170239 · Cited by 5

Impact of alternating amino acid sequences on beta-amyloid-induced neurotoxicity and neuroinflammation in Alzheimer's disease

Li, Z., Peng, M., Wang, C., Yang, J., Li, X., & Zhao, J. (2023) · Aging · doi:10.18632/aging.205095 · Cited by 4

Designing Novel Peptidic Inhibitors of Beta Amyloid Oligomerization

Roy, S. S. (2010) · Libraries and Cultural Resources (University of Calgary) · doi:10.5072/prism/17548 · Cited by 4

A putative role for PCSK9 in synaptic remodelling and plasticity in response to brain injury: implications for Alzheimer's disease

Jasmin, S. B. (2011) · eScholarship@McGill (McGill) · doi:10.82308/52384 · Cited by 3

Elucidation of Amyloid-Beta’s Gambit in Oligomerization: Truncated Aβ fragments of residues Aβ1-23, Aβ1-24 and Aβ1-25 rapidly seed to form SDS-stable, LMW Aβ oligomers that impair synaptic plasticityPreprint

Gil, B., Rose, J. L., Demurtas, D., Mancini, G., Sordet‐Dessimoz, J., Sorrentino, V., Rudinskiy, N., Frosch, M. P., Hyman, B. T., Moniatte, M., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.12.04.519021 · Cited by 3

Animal Models of Alzheimer’s Disease

Kiyota, T. (2013) · Springer protocols handbooks/Springer protocols · doi:10.1007/978-1-4614-8794-4_35 · Cited by 3

Anesthetics Promoting in vitro AβPP Metabolism and Amyloid-β Toxicity

Eckel, B. A., Blobner, M., & Rammes, G. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-100984 · Cited by 2

Amyloid beta 1-42 in cerebrospinal fluid is associated with cognitive plasticity

Uttner, I., Schurig, N., Arnim, C. A. F. V., Lange‐Asschenfeldt, C., Brettschneider, J., Riepe, M. W., & Tumani, H. (2011) · Psychiatry Research · doi:10.1016/j.psychres.2011.04.017 · Cited by 2

SMPL Synaptic Membranes: Nanodisc-Mediated Synaptic Membrane Mimetics Expand the Toolkit for Drug Discovery and the Molecular Cell Biology of Synapses

Bu, R. L., Clark, J. R., DiChiara, T., Sligar, S. G., & Klein, W. L. (2018) · Neuromethods · doi:10.1007/978-1-4939-8739-9_13 · Cited by 2

Amyloid fibrils are nanoparticles that target lysosomes.

Jakhria, T. (2014) · UPT. Syiah Kuala University Library (Syiah Kuala University) · Cited by 2

Safety, tolerability and immunogenicity of vaccine ALZ-101 in patients with early Alzheimer’s disease: randomised, controlled trial

Lovró, Z., Sandberg, A., Zetterberg, H., Pierrou, S. E., Parkkola, R., Sjögren, N., Scheinin, M., & Rinne, J. O. (2026) · Alzheimer s Research & Therapy · doi:10.1186/s13195-026-02082-9 · Cited by 2

Metformin enhances hippocampal excitatory synaptic transmission and preserves synaptic plasticity under amyloid-β oligomer-induced dysfunction

Arriagada, J., Ardiles, Á. O., Mery, E., Garay, C., Conejera, F., Herrera, E. A., Paula-Lima, A. C., & Muñoz, P. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.111116 · Cited by 1

The central role of T-cell memory in Alzheimer’s disease vaccination

Giunta, B. N., Ruscin, A., Salemi, J., Wolfson, A., Fernandez, F., & Tan, J. (2010) · Ageing Research · doi:10.4081/ar.2010.e5 · Cited by 1

Increased Detection of Aβ Oligomers in the Cerebrospinal Fluid of Alzheimer s Disease: Fact or Artifact?

Sancesario, G. (2012) · Journal of Molecular Biomarkers & Diagnosis · doi:10.4172/2155-9929.1000e107 · Cited by 1

Alzheimer’s Disease and Mechanism-Based Attempts to Enhance Cognition

Draffin, J. E., Knafo, S., & Heneka, M. T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-417042-1.00009-7 · Cited by 1

A preclinical screen to evaluate pharmacotherapies for the treatment of agitation in dementia

O‘Hare, E., Page, D., Curran, W. J., Hong, J.-S., & Kim, E. (2017) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000298 · Cited by 1

Anti-Amyloid-β Immunotherapy: A Leading Novel Avenue for Alzheimer's Disease

Babbar, R., Sharma, P., Sharma, T., Madaan, P., Arora, S., & Badavath, V. N. (2022) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557522666220524090354 · Cited by 1

The aging synapse: Synaptic proteome changes in mouse models of aging

Végh, M. J. (2012) · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) · Cited by 1

POTENTIAL OF ADENOSINE-SYSTEM-BASED THERAPIES IN THE TREATMENT OF NEUROIMMUNE DISORDERS

Peixoto, I. (2012) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · doi:10.34626/3cxd-am86 · Cited by 1

Structural and Toxic Properties of Protein Aggregates: Towards a Molecular Understanding of Alzheimer's Disease

Wang, L., & Campioni, S. (2011) · InTech eBooks · doi:10.5772/20922

Physico-chemical characterization of beta-amyloid oligomers and study of their function in biological processes at molecular level

Simon, D. (2011) · SZTE Repository of Dissertations (University of Szeged) · doi:10.14232/phd.1292

SPECIFIC AMYLOID-BETA OLIGOMERS IN HUMAN CEREBROSPINAL FLUID

Handoko, M. (2012) · University of Minnesota Digital Conservancy (University of Minnesota)

The Association Between Traumatic Brain Injury and Alzheimer's Disease: Mouse Models and Potential Mechanisms

Tran, H. (2011) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7gb223z

The Alzheimer s disease related gamma-secretase complex : Localization and novel interacting proteins

Hur, J. (2010) · Figshare

Synaptic elimination and the complement system in Alzhaimer's disease

Daborg, J. (2012) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Amyloid-β Protofibrils in Alzheimer´s Disease : Focus on Antibodies, Inflammation and Astrocytes

Söllvander, S. (2015) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Multipotent neural stem/progenitor cells as a model of genetic neuronal diseases

Kärkkäinen, V. (2012) · UEF eRepo (University of Eastern Finland)

Abeta(1-42) enhances neuronal excitability and disrupts synaptic plasticity by altering glutamate-recycling

Varga, E. (2015) · SZTE Repository of Dissertations (University of Szeged) · doi:10.14232/phd.2588

Aβ Conformation Dependent Antibodies and Alzheimer's Disease

Sehlin, D. (2010) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

The interplay between vascular and mitochondrial abnormalities in type 2 diabetes and Alzheimer’s disease

Carvalho, C. (2013) · Estudo Geral (Universidade de Coimbra)

Development of human and rodent based in vitro systems toward better translation of bench to bedside in vivo results

Berry, B. J. (2015) · Journal of International Crisis and Risk Communication Research

Amyloid aggregates: detection and interaction

Rahman, M. M. (2018) · Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences))

Cognitive Deficits in Neurodegenerative Disorders: Parkinson’s Disease and Alzheimer’s Disease

Bodis-Wollner, I. G., & Moreno, H. (2010) · Advances in neurobiology · doi:10.1007/978-1-4419-7104-3_9

Transcranial Magnetic Stimulation in Dementia: From Pathophysiology to Treatment

Koch, G. (2020) · Springer eBooks · doi:10.1007/978-3-030-43356-7_12

Customer Loyalty in E-Business.

Raggad, B. G., & Lawler, J. E. (2003) · International Conference on Enterprise Information Systems

Functional spreading of hyperexcitability induced by human and synthetic intracellular Aβ oligomersPreprint

Fernández-Pérez, E. J., Muñoz, B., Bascuñán, D., Peters, C., Riffo-Lepe, N., Espinoza, M. P., Morgan, P. J., Filippi, C., Bourboulou, R., Sengupta, U., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.16.332445

Estudos da seletividade e afinidade da interação de anticorpos de cadeia única NUsc a oligômeros do peptídeo β-amiloide

Carraro, M. F. (2021) · doi:10.11606/d.17.2021.tde-28012022-104158

Prion Protein Complex with mGluR5 Mediates Amyloid-ß Synaptic Loss in Alzheimer’s Disease

Roseman, G. P., Fu, L., & Strittmatter, S. M. (2023) · Springer eBooks · doi:10.1007/978-3-031-20565-1_22

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.

Anwyl, R., Klyubin, I. V., & ROWAN, M. (2008) · Arrow@dit (Dublin Institute of Technology)

Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo

Klyubin, I., Walsh, D. M., Lemere, C. A., Cullen, W. K., Shankar, G. M., Betts, V., Spooner, E. T., Jiang, L., Anwyl, R., Selkoe, D. J., et al. (2005) · Nature Medicine · doi:10.1038/nm1234 · Cited by 489

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., & Selkoe, D. J. (2002) · Nature · doi:10.1038/416535a · Cited by 4,291

Synaptic plasticity disruption by amyloid β protein: modulation by potential Alzheimer's disease modifying therapies

Rowan, M. J., Klyubin, I. V., Wang, Q., & Anwyl, R. (2005) · Biochemical Society Transactions · doi:10.1042/bst0330563 · Cited by 83

S1‐02–03: Synthetic Abeta dimers and Abeta dimers from CSF and Alzheimer brain disrupt synaptic plasticity and memory

Walsh, D. M. (2008) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2008.05.192