SHP2: a new target for pro‐senescence cancer therapies
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When apoptosis is blocked, various apoptotic stimuli can activate autophagy and JNK to induce autophagic cell death.
“when apoptosis is blocked, various apoptotic stimuli can activate autophagy and JNK to induce autophagic cell death”
From p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling (2017) · cites this paper as Serrano, 2015
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High expression of SHP2 predicts a promising prognosis in colorectal cancerPreprint
Liu, X., Li, M., Chen, L., Wen, F., Zheng, S. S., & Ge, W. (2022) · Research Square · doi:10.21203/rs.3.rs-1717423/v1
Mazeyrie, L. (2024) · theses.fr (ABES) · doi:10.70675/04dabd62z8f26z4393zac25z0070faaa4fb9
- Authors
- Serrano, M.
- Affiliations
- Spanish National Cancer Research Centre (ES)
- Corresponding author
- Serrano, Manuel
- ORCID
- Serrano, Manuel
- Venue
- The EMBO Journal
- Published
- 2015-04-27
- Volume
- 34
- Issue
- 11
- Pages
- 1439-1441
- ISSN
- 0261-4189 (ISSN-L)
- 1460-2075
- PMC
- PMC4474521
- OpenAlex
- W2043772448
- Cited by
- 12
- References
- 10
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 2 · 2020: 2 · 2019: 2 · 2017: 2 · 2015: 2
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The EMBO Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Tyrosine Phosphatases
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Keywords
- SHP2, cellular senescence, protein tyrosine phosphatase inhibition, breast cancer, senescence-associated inflammation, tumor cell proliferation
- MeSH terms
- Animals, Female, Humans, Mammary Neoplasms, Animal, Cellular Senescence, Protein Tyrosine Phosphatase, Non-Receptor Type 11
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