Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine

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2. A second Warburg‐like effect in cancer metabolism: The metabolic shift of glutamine‐derived nitrogen
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3. Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice
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5. Metabolic reprogramming sustains cancer cell survival following extracellular matrix detachment
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6. Cancer cell survival depends on collagen uptake into tumor-associated stroma
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7. RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis
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8. Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial Function
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9. Pre-clinical investigation of STAT3 pathway in bladder cancer: Paving the way for clinical translation.
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10. Cancer metabolism and intervention therapy
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13. Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo
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14. The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice
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15. Glutathione Synthesis in Cancer Cells
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16. ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway
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17. Overview of Cancer Metabolism and Signaling Transduction
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18. Enhanced Glutaminolysis Drives Hypoxia-Induced Chemoresistance in Pancreatic Cancer
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19. KRAS mutation: The booster of pancreatic ductal adenocarcinoma transformation and progression
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20. Arginine: Challenges and opportunities of this two-faced molecule in cancer therapy
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21. A micropeptide XBP1SBM encoded by lncRNA promotes angiogenesis and metastasis of TNBC via XBP1s pathway
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22. Targeting glutamine metabolism as a potential target for cancer treatment
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23. Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment
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24. Glutamine synthetase licenses APC/C-mediated mitotic progression to drive cell growth
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25. Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy
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26. Subgroup-specific prognostic signaling and metabolic pathways in pediatric medulloblastoma
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28. Amino acid metabolism‐related gene expression‐based risk signature can better predict overall survival for glioma
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29. Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation
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30. The pathways related to glutamine metabolism, glutamine inhibitors and their implication for improving the efficiency of chemotherapy in triple-negative breast cancer
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31. EWS‐FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine‐glycine biosynthesis
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32. Increased Amino Acid Uptake Supports Autophagy-Deficient Cell Survival upon Glutamine Deprivation
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33. Investigation of different targeting decorations effect on the radiosensitizing efficacy of albumin-stabilized gold nanoparticles for breast cancer radiation therapy
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34. Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion
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36. Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX
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37. Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer
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38. Comorbidity-associated glutamine deficiency is a predisposition to severe COVID-19
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39. The glutamine antagonist prodrug JHU-083 slows malignant glioma growth and disrupts mTOR signaling
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41. PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
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42. Glutamine mitigates murine burn sepsis by supporting macrophage M2 polarization through repressing the SIRT5-mediated desuccinylation of pyruvate dehydrogenase
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43. Glutamine metabolic reprogramming in hepatocellular carcinoma
    Yanyan Ye, Bodong Yu, Hua Wang, F. Yi · 2023 · Frontiers in Molecular Biosciences
44. Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA
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45. Immunometabolism: A new target for improving cancer immunotherapy
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48. Biosynthetic energy cost for amino acids decreases in cancer evolution
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49. Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis
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50. GLS1 depletion inhibited colorectal cancer proliferation and migration via redox/Nrf2/autophagy-dependent pathway
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51. Beyond the Warburg Effect: N-Myc Contributes to Metabolic Reprogramming in Cancer Cells
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52. MYCN and Metabolic Reprogramming in Neuroblastoma
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53. Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis
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54. Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target
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55. Glutamine metabolism: from proliferating cells to cardiomyocytes
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56. Primary cilia sense glutamine availability and respond via asparagine synthetase
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57. Elemene induces cell apoptosis via inhibiting glutathione synthesis in lung adenocarcinoma
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58. The Metabolic Interplay between Cancer and Other Diseases
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59. Metabolic Pathways, Enzymes, and Metabolites: Opportunities in Cancer Therapy
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60. Ibrutinib Resistance Is Reduced by an Inhibitor of Fatty Acid Oxidation in Primary CLL Lymphocytes
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61. Endoplasmic Reticulum Stress and Tumor Microenvironment in Bladder Cancer: The Missing Link
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65. Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria
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67. Targeted Glucose or Glutamine Metabolic Therapy Combined With PD-1/PD-L1 Checkpoint Blockade Immunotherapy for the Treatment of Tumors - Mechanisms and Strategies
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68. Glutamine metabolism in cancers: Targeting the oxidative homeostasis
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69. Pancreatic stellate cells exploit Wnt/β-catenin/TCF7-mediated glutamine metabolism to promote pancreatic cancer cells growth
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70. The role of the glutamine transporter ASCT2 in antineoplastic therapy
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71. Glutamate - A multifaceted molecule: Endogenous neurotransmitter, controversial food additive, design compound for anti-cancer drugs. A critical appraisal
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74. Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells
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75. Reprogramming of mitochondrial proline metabolism promotes liver tumorigenesis
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77. Sorting nexin 27 (SNX27) regulates the trafficking and activity of the glutamine transporter ASCT2
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82. A Glutamine-Rich Carrier Efficiently Delivers Anti-CD47 siRNA Driven by a “Glutamine Trap” To Inhibit Lung Cancer Cell Growth
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83. Targeting glutaminase-mediated glutamine dependence in papillary thyroid cancer
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97. UGCG influences glutamine metabolism of breast cancer cells
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98. WEE1 inhibition induces glutamine addiction in T-cell acute lymphoblastic leukemia
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