The DOI matches its Crossref record; 59 of the 60 references it cites were found in a registry or an index.
Childhood Exposure to Adversity and Risk of Substance-Use Disorder in Two American Indian Populations: The Meditational Role of Early Substance-Use Initiation
Open accessAbstract
OBJECTIVE: We examined the relationship of childhood exposure to adversity and risk of substance-use disorder in two culturally distinct American Indian reservation communities, exploring both the role of early initiation of substance use in mediating this relationship and variation in risk across types of adversity exposure. METHOD: The American Indian Service Utilization, Psychiatric Epidemiology, Risk and Protective Factors Project provided data from 2,927 American Indians on the occurrence and age at onset of adversities, substance use, and substance-use-disorder symptoms. RESULTS: The risk of substance-use disorder associated with early adversity was explained partially by early initiation of substance use. Three types of adversity (major childhood events, traumas, and witnessed violence) were associated with early onset of substance use and increased risk of substance-use disorder. Gender and tribe were also related to variation in both early substance use and substance-use disorder. CONCLUSIONS: Early exposure to adverse events was associated with early substance use and the subsequent development of substance-use disorders among American Indians. public health initiatives targeting substance use and substance-use disorders in American Indian communities should include efforts to help children in these communities cope with adversities they encounter.
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“Trauma and exposure to stress are also highly prevalent in the American Indian community and are highly comorbid with substance use (Ehlers et al., 2013; Whitesell et al., 2009).”
From Assessment of culture and environment in the Adolescent Brain and Cognitive Development Study: Rationale, description of measures, and early data (2018) · cites this paper as Whitesell et al., 2009
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1 of the 60 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- aneshensel, c.s. outcomes of the stress process. in: horwitz, a.v. and scheid, t.l. (eds.) a handbook for the study of Mental health: social contexts, theories, and systems, New York: cambridge univ. press, 1999, pp. 211-227.
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Steele, P. D. (2026) · Oxford University Press eBooks · doi:10.1093/9780190275662.002.0008
Dagley, K. C. (2011) · ScholarsArchive (Brigham Young University)
Metadata
- Authors
- Whitesell, N. R., Beals, J., Mitchell, C. M., Manson, S. M., Turner, R. J., & AI-SUPERPFP Team
- Affiliations
- Colorado School of Public Health (US)
- Florida State University (US)
- Venue
- Journal of Studies on Alcohol and Drugs
- Publisher
- Alcohol Research Documentation, Inc.
- Published
- 2009-11
- Volume
- 70
- Issue
- 6
- Pages
- 971-981
- ISSN
- 1937-1888 (ISSN-L)
- 1938-4114
- PMC
- PMC2776127
- OpenAlex
- W2037405610
- Cited by
- 102
- References
- 60
- Citations by year
- 2026: 26 · 2025: 4 · 2024: 5 · 2023: 9 · 2022: 7 · 2021: 6 · 2020: 6 · 2019: 5 · 2018: 5 · 2017: 5 · 2016: 7 · 2015: 4 · 2014: 1 · 2013: 4 · 2012: 4
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Studies on Alcohol and Drugs (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (P01MH042473, R01MH048174)
- National Institute on Drug Abuse (R01DA014817, R01DA017803)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Health › Indigenous Health, Education, and Rights
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Keywords
- childhood adversity, substance use disorders, Native Americans, reservation communities, childhood trauma, witnessing violence, mediation, gender differences, tribal differences, risk and protective factors
- MeSH terms
- Adolescent, Adult, Age Factors, Child, Cross-Cultural Comparison, Data Collection, Female, Humans, Indians, North American, Male, Middle Aged, Risk Factors, Sex Factors, United States, Age of Onset, Substance-Related Disorders, Young Adult
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