The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Evaluation of maternal thyroid function during pregnancy: the importance of using gestational age-specific reference intervals
Abstract
Background: Maternal thyroid dysfunction has been associated with a variety of adverse pregnancy outcomes. Laboratory measurement of thyroid function plays an important role in the assessment of maternal thyroid health. However, occult thyroid disease and physiologic changes associated with pregnancy can complicate interpretation of maternal thyroid function tests (TFTs). Objective and methods: To 1) establish the prevalence of laboratory evidence for autoimmune thyroid disease (AITD) in pregnant women; 2) establish gestational age-specific reference intervals for TFTs in women without AITD; and 3) examine the influence of reference intervals on the interpretation of TFT in pregnant women. Serum samples were collected from 2272 pregnant women, and TFT performed. Gestational age-specific reference intervals were determined in women without AITD, and then compared with the non-pregnant assay-specific reference intervals for interpretation of testing results. Results: Thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (Tg-Ab) were positive in 10.4 and 15.7% of women respectively. TPO-Ab level was related to maternal age, but TPO-Ab status, Tg-Ab status, and Tg-Ab level were not. Women with TSH > 3.0 mIU/l were significantly more likely to be TPO-Ab positive. Gestational age-specific reference intervals for TFT were significantly different from non-pregnant normal reference intervals. Interpretation of TFT in pregnant women using non-pregnant reference intervals could potentially result in misclassification of a significant percentage of results (range: 5.6–18.3%). Conclusion: Laboratory evidence for thyroid dysfunction was common in this population of pregnant women. Accurate classification of TFT in pregnant women requires the use of gestational age-specific reference intervals.
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The Colorado Thyroid Disease Prevalence Study
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Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease
(2003) · Thyroid · doi:10.1089/105072503321086962 · Cited by 1,212
Subclinical hypothyroidism and pregnancy outcomes
Casey, B. M., Dashe, J. S., Wells, C. E., McIntire, D. D., Byrd, W., Leveno, K. J., & Cunningham, F. G. (2005) · Obstetrics & Gynecology · doi:10.1097/01.aog.0000152345.99421.22 · Cited by 903
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Cited by
Stagnaro-Green, A., Abalovich, M., Alexander, E., Azizi, F., Mestman, J., Negro, R., Nixon, A., Pearce, E. N., Soldin, O. P., Sullivan, S., et al. (2011) · Thyroid · doi:10.1089/thy.2011.0087 · Cited by 2,942
Alexander, E. K., Pearce, E. N., Brent, G. A., Brown, R. S., Chen, H., Dosiou, C., Grobman, W. A., Laurberg, P., Lazarus, J. H., Mandel, S. J., et al. (2017) · Thyroid® · doi:10.1089/thy.2016.0457 · Cited by 2,731
Garber, J. R., Cobin, R. H., Gharib, H., Hennessey, J. V., Klein, I., Mechanick, J. I., Pessah-Pollack, R., Singer, P. A., & Woeber, K. A. (2012) · Endocrine Practice · doi:10.4158/ep12280.gl · Cited by 1,567
Thyroid Function and Human Reproductive Health
Krassas, G. E., Poppe, K., & Glinoer, D. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0041 · Cited by 1,223
Garber, J. R., Cobin, R. H., Gharib, H., Hennessey, J. V., Klein, I., Mechanick, J. I., Pessah-Pollack, R., Singer, P. A., & Woeber for the American Association, K. A. (2012) · Thyroid · doi:10.1089/thy.2012.0205 · Cited by 1,053
Treatment with thyroid hormone
Biondi, B., & Wartofsky, L. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1083 · Cited by 259
Ethnic differences in maternal thyroid parameters during pregnancy: the Generation R study
Korevaar, T. I. M., Medici, M., de Rijke, Y. B., Visser, W., de Muinck Keizer-Schrama, S. M. P. F., Jaddoe, V. W. V., Hofman, A., Ross, H. A., Visser, W. E., Hooijkaas, H., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-2005 · Cited by 150
Boas, M., Forman, J. L., Juul, A., Feldt-Rasmussen, U., Skakkebæk, N. E., Hilsted, L., Chellakooty, M., Larsen, T., Larsen, J. F., Petersen, J. H., et al. (2009) · European Journal of Endocrinology · doi:10.1530/eje-09-0579 · Cited by 74
Thyrotropin Isoforms: Implications for Thyrotropin Analysis and Clinical Practice
Estrada, J. M., Soldin, D., Buckey, T. M., Burman, K. D., & Soldin, O. P. (2014) · Thyroid® · doi:10.1089/thy.2013.0119 · Cited by 64
Metadata
- Authors
- Stricker, R., Echenard, M., Eberhart, R., Chevailler, M.-C., Perez, V, Quinn, F. A., & Stricker, R.
- Venue
- European Journal of Endocrinology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-10
- Volume
- 157
- Issue
- 4
- Pages
- 509-514
- ISSN
- 0804-4643 (ISSN-L)
- 1479-683X
- OpenAlex
- W2137845823
- Cited by
- 276
- References
- 6
- FWCI
- 8.73
- Type
- journal article
- Language
- en
- Open access
- closed
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