Reduced microvascular perfusion and reactivity in adult GH deficient patients is restored by GH replacement

Hana, V; Prazny, M; Marek, J; Skrha, J; Justova, V

doi:10.1530/eje.0.1470333

Reduced microvascular perfusion and reactivity in adult GH deficient patients is restored by GH replacement

BACKGROUND: An increased cardiovascular risk and mortality in hypopituitary patients receiving conventional hormonal treatment without GH replacement have been shown in several studies. Various atherogenic risk factors including endothelial dysfunction - an early event in the atherogenesis - are …