NRF2 immunolocalization in human breast cancer patients as a prognostic factor

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer.

Paik, S., Shak, S., Tang, G., Kim, C., Baker, J., Cronin, M., Baehner, F., Walker, M. G., Watson, D., Park, T., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041588 · Cited by 6,009 · see citing works

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

Liang, C.-C., Park, A. Y., & Guan, J.-L. (2007) · Nature Protocols · doi:10.1038/nprot.2007.30 · Cited by 4,696 · see citing works

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

Hammond, M. E., Hayes, D. F., Dowsett, M., Allred, D. C., Hagerty, K. L., Badve, S., Fitzgibbons, P. L., Francis, G. D., Goldstein, N. S., Hayes, M. M., et al. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.25.6529 · Cited by 4,217 · see citing works

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y., Ueno, I., Sakamoto, A., Tong, K. I., et al. (2010) · Nature Cell Biology · doi:10.1038/ncb2021 · Cited by 2,422 · see citing works

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

DeNicola, G. M., Karreth, F. A., Humpton, T. J., Gopinathan, A., Wei, C., Frese, K., Mangal, D., Yu, K. H., Yeo, C. J., Calhoun, E. S., et al. (2011) · Nature · doi:10.1038/nature10189 · Cited by 2,277 · see citing works

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

Taguchi, K., Motohashi, H., & Yamamoto, M. (2011) · Genes to Cells · doi:10.1111/j.1365-2443.2010.01473.x · Cited by 1,478 · see citing works

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

Mitsuishi, Y., Taguchi, K., Kawatani, Y., Shibata, T., Nukiwa, T., Aburatani, H., Yamamoto, M., & Motohashi, H. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.05.016 · Cited by 1,395 · cited 3× · see citing works

Systemic Spread Is an Early Step in Breast Cancer

Hüsemann, Y., Geigl, J. B., Schubert, F., Musiani, P., Meyer, M., Burghart, E., Forni, G., Eils, R., Fehm, T. N., Riethmüller, G., et al. (2008) · Cancer Cell · doi:10.1016/j.ccr.2007.12.003 · Cited by 1,175 · see citing works

The cytoprotective role of the Keap1–Nrf2 pathway

Baird, L., & Dinkova‐Kostova, A. T. (2011) · Archives of Toxicology · doi:10.1007/s00204-011-0674-5 · Cited by 1,029 · see citing works

Ki-67 as prognostic marker in early breast cancer: a meta-analysis of published studies involving 12 155 patients

de Azambuja, E., Cardoso, F., de Castro, G., Colozza, M., Mano, M. S., Durbecq, V., Sotiriou, C. P., Larsimont, D., Piccart, M. J., & Paesmans, M. (2007) · British Journal of Cancer · doi:10.1038/sj.bjc.6603756 · Cited by 954 · see citing works

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

Surh, Y., Kundu, J. K., & Na, H. (2008) · Planta Medica · doi:10.1055/s-0028-1088302 · Cited by 759 · see citing works

Sequestosome 1/p62 Is a Polyubiquitin Chain Binding Protein Involved in Ubiquitin Proteasome Degradation

Seibenhener, M. L., Babu, J. R., Geetha, T., Wong, H. C., Krishna, N. R., & Wooten, M. W. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.18.8055-8068.2004 · Cited by 710 · see citing works

Dual roles of Nrf2 in cancer

LAU, A., VILLENEUVE, N., Sun, Z., Wong, P. K., & Zhang, D. (2008) · Pharmacological Research · doi:10.1016/j.phrs.2008.09.003 · Cited by 645 · see citing works

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

Inami, Y., Waguri, S., Sakamoto, A., Kouno, T., Nakada, K., Hino, O., Watanabe, S., Ando, J., Iwadate, M., Yamamoto, M. P., et al. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201102031 · Cited by 602 · see citing works

Genetic Alteration of Keap1 Confers Constitutive Nrf2 Activation and Resistance to Chemotherapy in Gallbladder Cancer

Shibata, T., Kokubu, A., Gotoh, M., Ojima, H., Ohta, T., Yamamoto, M. P., & Hirohashi, S. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.06.082 · Cited by 470 · see citing works

Nrf2 and Keap1 Abnormalities in Non–Small Cell Lung Carcinoma and Association with Clinicopathologic Features

Solis, L. M., Behrens, C., Dong, W., Suraokar, M. B., Ozburn, N. C., Moran, C. A., Corvalán, A. H., Biswal, S. S., Swisher, S. G., Bekele, B. N., et al. (2010) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-3352 · Cited by 430 · see citing works

Prognostic value of proliferation in invasive breast cancer: a review: Table 1

van Diest, P. J., van der Wall, E., & Baak, J. P. A. (2004) · Journal of Clinical Pathology · doi:10.1136/jcp.2003.010777 · Cited by 388 · see citing works

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

Zhang, P., Singh, A., Yegnasubramanian, S., Esopi, D., Kombairaju, P., Bodas, M., Wu, H., Bova, G. S., & Biswal, S. S. (2010) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-09-0589 · Cited by 376 · see citing works

RNAi -Mediated Silencing of Nuclear Factor Erythroid-2–Related Factor 2 Gene Expression in Non–Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

Singh, A., Boldin‐Adamsky, S., Thimmulappa, R. K., Rath, S. K., Ashush, H., Coulter, J. B., Blackford, A. L., Goodman, S. N., Bunz, F., Watson, W. H., et al. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-1401 · Cited by 371 · see citing works

Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues

Siegel, D. M., & Ross, D. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00310-5 · Cited by 300 · see citing works

NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1α

Kim, T., Hur, E.-G., Kang, S., Kim, J., Thapa, D., Lee, Y. M., Ku, S., Jung, Y., & Kwak, M. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-3007 · Cited by 292 · see citing works

Keap1 Mutations and Nrf2 Pathway Activation in Epithelial Ovarian Cancer

Konstantinopoulos, P. A., Spentzos, D., Fountzilas, E., Francoeur, N. J., Sanisetty, S., Grammatikos, A. P., Hecht, J. L., & Cannistra, S. A. (2011) · Cancer Research · doi:10.1158/0008-5472.can-10-4668 · Cited by 272 · see citing works

Predictive Value of Tumor Ki-67 Expression in Two Randomized Trials of Adjuvant Chemoendocrine Therapy for Node-Negative Breast Cancer

Viale, G., On the behalf of the International Breast Cancer Study Group, Regan, M. M., On the behalf of the International Breast Cancer Study Group, Mastropasqua, M. G., On the behalf of the International Breast Cancer Study Group, Maffini, F. A., On the behalf of the International Breast Cancer Study Group, Maiorano, E., On the behalf of the International Breast Cancer Study Group, et al. (2008) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm289 · Cited by 247 · see citing works

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

Lister, A., Nedjadi, T., Kitteringham, N. R., Campbell, F., Costello, E., Lloyd, B. H., Copple, I. M., Williams, S. J., Owen, A., Neoptolemos, J. P., et al. (2011) · Molecular Cancer · doi:10.1186/1476-4598-10-37 · Cited by 243 · see citing works

The p62 Scaffold Regulates Nerve Growth Factor-induced NF-κB Activation by Influencing TRAF6 Polyubiquitination

Wooten, M. W., Geetha, T., Seibenhener, M. L., Babu, J. R., Díaz-Meco, M. T., & Moscat, J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.c500237200 · Cited by 225 · see citing works

NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer

Shibata, T., Kokubu, A., Saito, S., Narisawa-Saito, M., Sasaki, H., Aoyagi, K., Yoshimatsu, Y., Tachimori, Y., Kushima, R., Kiyono, T., et al. (2011) · Neoplasia · doi:10.1593/neo.11750 · Cited by 224 · see citing works

Selective Autophagy in Cancer Development and Therapy

Đikić, I., Johansen, T., & Kirkin, V. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4027 · Cited by 212 · see citing works

Accumulation of p62/ SQSTM 1 is associated with poor prognosis in patients with lung adenocarcinoma

Inoue, D., Suzuki, T., Mitsuishi, Y., Miki, Y., Suzuki, S., Sugawara, S., Watanabe, M., Sakurada, A., Endo, C., Uruno, A., et al. (2012) · Cancer Science · doi:10.1111/j.1349-7006.2012.02216.x · Cited by 204 · see citing works

MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis

Singh, B. P., Ronghe, A. M., Chatterjee, A., Bhat, N. K., & Bhat, H. K. (2013) · Carcinogenesis · doi:10.1093/carcin/bgt026 · Cited by 200 · see citing works

Survival in patients with metastatic recurrent breast cancer after adjuvant chemotherapy

Tevaarwerk, A. J., Gray, R. J., Schneider, B. P., Smith, M. L., Wagner, L. I., Fetting, J. H., Davidson, N. E., Goldstein, L. J., Miller, K. D., & Sparano, J. A. (2012) · Cancer · doi:10.1002/cncr.27819 · Cited by 196 · see citing works

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

Uruno, A., & Motohashi, H. (2011) · Nitric Oxide · doi:10.1016/j.niox.2011.02.007 · Cited by 187 · see citing works

Integrating gene and protein expression data: pattern analysis and profile mining

Cox, B., Kislinger, T., & Emili, A. (2005) · Methods · doi:10.1016/j.ymeth.2004.08.021 · Cited by 176 · see citing works

Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells

Kim, S. K., Yang, J. W., Kim, M. R., Roh, S. H., Kim, H. G., Lee, K. Y., Jeong, H. G., & Kang, K. W. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.05.011 · Cited by 171 · see citing works

Systemic Distribution of Steroid Sulfatase and Estrogen Sulfotransferase in Human Adult and Fetal Tissues

Miki, Y., Nakata, T., Suzuki, T., Darnel, A. D., Moriya, T., Kaneko, C., Hidaka, K., Shiotsu, Y., Kusaka, H., & Sasano, H. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020670 · Cited by 171 · see citing works

Structure of the Ubiquitin-associated Domain of p62 (SQSTM1) and Implications for Mutations That Cause Paget's Disease of Bone

Ciani, B., Layfield, R., Cavey, J. R., Sheppard, P. W., & Searle, M. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307416200 · Cited by 128 · see citing works

PB1 Domain Interaction of p62/Sequestosome 1 and MEKK3 Regulates NF-κB Activation

Nakamura, K., Kimple, A. J., Siderovski, D. P., & Johnson, G. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.065102 · Cited by 125 · see citing works

The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease

Rolland, P., Madjd, Z., Durrant, L. G., Ellis, I. O., Layfield, R., & Spendlove, I. (2007) · Endocrine Related Cancer · doi:10.1677/erc.1.01312 · Cited by 115 · see citing works

Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage and is associated with inhibition of estrogen-induced breast cancer

Singh, B. P., & Bhat, H. K. (2012) · Carcinogenesis · doi:10.1093/carcin/bgs300 · Cited by 108 · see citing works

Nuclear cyclin B1 in human breast carcinoma as a potent prognostic factor

Suzuki, T., Urano, T., Miki, Y., Moriya, T., Akahira, J., Ishida, T., Horie, K., Inoue, S., & Sasano, H. (2007) · Cancer Science · doi:10.1111/j.1349-7006.2007.00444.x · Cited by 104 · see citing works

Expression of autophagy‐related markers beclin‐1, light chain 3A, light chain 3B and p62 according to the molecular subtype of breast cancer

Choi, J., Jung, W., & Koo, J. S. (2012) · Histopathology · doi:10.1111/his.12002 · Cited by 103 · see citing works

Stress Resistance in the Naked Mole-Rat: The Bare Essentials – A Mini-Review

Lewis, K. N., Mele, J., Hornsby, P. J., & Buffenstein, R. (2012) · Gerontology · doi:10.1159/000335966 · Cited by 100 · see citing works

Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy

Loignon, M., Miao, W., Hu, L., Bier, A., Bismar, T. A., Scrivens, P. J., Mann, K. K., Basik, M., Bouchard, A., Fiset, P., et al. (2009) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-08-1186 · Cited by 99 · see citing works

Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates Drug Resistance in Pancreatic Cancer Cells

Hong, Y. B., Kang, H. J., Kwon, S. Y., Kim, H. J., Kwon, K. Y., Cho, C. H., Lee, J., Kallakury, B., & Bae, I. (2010) · Pancreas · doi:10.1097/mpa.0b013e3181c31314 · Cited by 91 · see citing works

Genetic Polymorphisms and Protein Expression of NRF2 and Sulfiredoxin Predict Survival Outcomes in Breast Cancer

Hartikainen, J. M., Tengström, M., Kosma, V.-M., Kinnula, V. L., Mannermaa, A., & Soini, Y. (2012) · Cancer Research · doi:10.1158/0008-5472.can-12-1474 · Cited by 89 · cited 2× · see citing works

Oxidative stress and counteracting mechanisms in hormone receptor positive, triple-negative and basal-like breast carcinomas

Karihtala, P., Kauppila, S., Soini, Y., & Arja-Jukkola-Vuorinen (2011) · BMC Cancer · doi:10.1186/1471-2407-11-262 · Cited by 87 · see citing works

Correlation of Nrf2, HO-1, and MRP3 in Gallbladder Cancer and Their Relationships to Clinicopathologic Features and Survival

Wang, J., Zhang, M., Zhang, L., Cai, H., Zhou, S., Zhang, J., & Wang, Y. (2010) · Journal of Surgical Research · doi:10.1016/j.jss.2010.05.058 · Cited by 75 · see citing works

Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene

Becks, L., Prince, M., Burson, H. C., Christophe, C., Broadway, M., Itoh, K., Yamamoto, M. P., Mathis, J. M., Orchard, E. A., Shi, R., et al. (2010) · BMC Cancer · doi:10.1186/1471-2407-10-540 · Cited by 71 · see citing works

Early growth responsive gene 3 in human breast carcinoma: a regulator of estrogen-meditated invasion and a potent prognostic factor

Suzuki, T., Inoue, A., Miki, Y., Moriya, T., Akahira, J., Ishida, T., Hirakawa, H., Yamaguchi, Y., Hayashi, S., & Sasano, H. (2007) · Endocrine Related Cancer · doi:10.1677/erc-06-0005 · Cited by 67 · see citing works

Nuclear factor-erythroid 2-related factor 2 as a chemopreventive target in colorectal cancer

Saw, C. L. L., & Kong, A. T. (2011) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2011.553602 · Cited by 51 · see citing works

CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells

Artus, C., Maquarre, E., Moubarak, R. S., Delettre, C., Jasmin, C., Susín, S. A., & Robert-Lézénès, J. (2006) · Oncogene · doi:10.1038/sj.onc.1209581 · Cited by 50 · see citing works

Nrf2 expression in endometrial serous carcinomas and its precancers.

Chen, N., Yi, X., Abushahin, N., Pang, S., Zhang, D., Kong, B., & Zheng, W. (2010) · PubMed Central · Cited by 31 · see citing works

The expression of NAD(P)H:quinone oxidoreductase 1 is increased along with NF-κB p105/p50 in human cutaneous melanomas

Li (2010) · Oncology Reports · doi:10.3892/or_00000722 · Cited by 29 · see citing works

Evaluation of Nrf2 and IGF-1 expression in benign, premalignant and malignant gastric lesions

Wang, H., Zhou, C., Song, S., Chen, P., Xu, W., Liu, B., Zhu, K., Yu, W., Wu, H., Wang, H.-J., et al. (2011) · Pathology - Research and Practice · doi:10.1016/j.prp.2010.12.009 · Cited by 27 · see citing works

NQO1 expression correlates inversely with NFκB activation in human breast cancer

Jamshidi, M., Bártková, J., Greco, D., Tommiska, J., Fagerholm, R., Aittomäki, K., Mattson, J., Villman, K., Vrtěl, R., Lukas, J., et al. (2011) · Breast Cancer Research and Treatment · doi:10.1007/s10549-011-1629-5 · Cited by 24 · see citing works

Opposite effects of arsenic trioxide on the Nrf2 pathway in oral squamous cell carcinoma in vitro and in vivo

Zhang, X., Su, Y., Zhang, M., & Sun, Z. (2011) · Cancer Letters · doi:10.1016/j.canlet.2011.12.005 · Cited by 23 · see citing works

Prognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma.

Wakai, T., Shirai, Y., Sakata, J., Matsuda, Y., Korita, P. V., Takamura, M., Ajioka, Y., & Hatakeyama, K. (2011) · PubMed Central · Cited by 21 · see citing works

Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: A potential mechanism of therapeutic limitation of mTOR inhibitor

Iida, S., Miki, Y., Ono, K., Akahira, J., Nakamura, Y., Suzuki, T., & Sasano, H. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.11.024 · Cited by 20 · see citing works

Analysis for Localization of Steroid Sulfatase in Human Tissues

Suzuki, T., Miki, Y., Fukuda, T., Nakata, T., Moriya, T., & Sasano, H. (2005) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(05)00018-2 · Cited by 11 · see citing works

Abstract 5081: Inhibiting DNA double strand break repair for alpha radioimmunotherapy

Hong, S., Hobbs, R. F., Shao, C., & Sgouros, G. (2011) · Cancer Research · doi:10.1158/1538-7445.am2011-5081 · Cited by 10 · see citing works

Abstract 5537: Quantitative multiplexed SRM analysis of oncogenic receptors in FFPE colorectal carcinoma tissue

Hembrough, T., Thyparambil, S. P., Liao, W., Darfler, M. M., Krizman, D. B., Adams, R., & Burrows, J. (2012) · Cancer Research · doi:10.1158/1538-7445.am2012-5537 · Cited by 5 · see citing works

Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging

Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03562-9 · Cited by 2,638 · see citing works

The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis

Yamamoto, M., Kensler, T. W., & Motohashi, H. (2018) · Physiological Reviews · doi:10.1152/physrev.00023.2017 · Cited by 1,968 · see citing works

Clinical Relevance of Biomarkers of Oxidative Stress

Frijhoff, J., Winyard, P. G., Žarković, N., Davies, S. S., Stocker, R., Cheng, D., Knight, A. R., Taylor, E., Oettrich, J., Ruskovska, T., et al. (2015) · Antioxidants and Redox Signaling · doi:10.1089/ars.2015.6317 · Cited by 918 · see citing works

The role of oxidative stress on breast cancer development and therapy

Hecht, F., Pessôa, C. F., Gentile, L. B., Rosenthal, D., de Carvalho, D. P., & Fortunato, R. S. (2016) · Tumor Biology · doi:10.1007/s13277-016-4873-9 · Cited by 304 · see citing works

The Role of Nrf2 Activity in Cancer Development and Progression

Zimța, A., Cenariu, D., Irimie, A., Magdo, L., Nabavi, S. M., Atanasov, A. G., & Berindan‐Neagoe, I. (2019) · Cancers · doi:10.3390/cancers11111755 · Cited by 298 · see citing works

Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation

Thiruvengadam, M., Venkidasamy, B., Subramanian, U., Samynathan, R., Shariati, M. A., Ребезов, М. Б., Girish, S., Thangavel, S., Dhanapal, A. R., Fedoseeva, N. A., et al. (2021) · Antioxidants · doi:10.3390/antiox10121859 · Cited by 282 · see citing works

NRF2 addiction in cancer cells

Kitamura, H., & Motohashi, H. (2018) · Cancer Science · doi:10.1111/cas.13537 · Cited by 275 · see citing works

Roles of Nrf2 in cell proliferation and differentiation

Murakami, S., & Motohashi, H. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.06.030 · Cited by 221 · see citing works

Targeting ferroptosis in breast cancer

Li, Z., Chen, L., Chen, C., Zhou, Y., Hu, D., Yang, J., Chen, Y., Zhuo, W., Mao, M., Zhang, X., et al. (2020) · Biomarker Research · doi:10.1186/s40364-020-00230-3 · Cited by 204 · see citing works

The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies

Jaganjac, M., Milković, L., Šunjić, S. B., & Žarković, N. (2020) · Antioxidants · doi:10.3390/antiox9111151 · Cited by 164 · see citing works

Lithocholic Acid, a Metabolite of the Microbiome, Increases Oxidative Stress in Breast Cancer

Kovács, P., Csonka, T., Kovàcs, T., Sári, Z., Ujlaki, G., Sipos, A. A., Karányi, Z., Szeőcs, D., Hegedűs, C., Uray, K., et al. (2019) · Cancers · doi:10.3390/cancers11091255 · Cited by 120 · see citing works

Deoxynyboquinones as NQO1-Activated Cancer Therapeutics

Parkinson, E. I., & Hergenrother, P. J. (2015) · Accounts of Chemical Research · doi:10.1021/acs.accounts.5b00365 · Cited by 106 · see citing works

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers

Okazaki, K., Anzawa, H., Liu, Z., Ota, N., Kitamura, H., Onodera, Y., Alam, M. M., Matsumaru, D., Suzuki, T., Katsuoka, F., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19593-0 · Cited by 97 · see citing works

Luteolin Inhibits Breast Cancer Stemness and Enhances Chemosensitivity through the Nrf2-Mediated Pathway

Tsai, K.-J., Tsai, H.-Y., Tsai, C., Chen, T., Hsieh, T., Chen, C., Mbuyisa, L., Huang, Y., & Lin, M. (2021) · Molecules · doi:10.3390/molecules26216452 · Cited by 92 · see citing works

Mitochondrial “power” drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer

Fiorillo, M., Sotgia, F., Sisci, D., Cappello, A. R., & Lisanti, M. P. (2017) · Oncotarget · doi:10.18632/oncotarget.15852 · Cited by 77 · see citing works

Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs

Telkoparan‐Akillilar, P., Süzen, S., & Saso, L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20082025 · Cited by 66 · see citing works

Metabolic features of cancer cells in NRF2 addiction status

Okazaki, K., Papagiannakopoulos, T., & Motohashi, H. (2020) · Biophysical Reviews · doi:10.1007/s12551-020-00659-8 · Cited by 57 · see citing works

The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis

Almeida, M., Soares, M., Ramalhinho, A. C., Fonseca-Moutinho, J. A., Breitenfeld, L., & Pereira, L. C. (2019) · Breast Cancer Research and Treatment · doi:10.1007/s10549-019-05494-4 · Cited by 57 · see citing works

Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients

Kanamori, M., Higa, T., Sonoda, Y., Murakami, S., Dodo, M., Kitamura, H., Taguchi, K., Shibata, T., Watanabe, M., Suzuki, H., et al. (2014) · Neuro-Oncology · doi:10.1093/neuonc/nou282 · Cited by 57 · see citing works

IL-11 contribution to tumorigenesis in an NRF2 addiction cancer model

Kitamura, H., Onodera, Y., Murakami, S., Suzuki, T., & Motohashi, H. (2017) · Oncogene · doi:10.1038/onc.2017.236 · Cited by 54 · see citing works

Involvement of NRF2 in Breast Cancer and Possible Therapeutical Role of Polyphenols and Melatonin

Tascioglu Aliyev, A., Panieri, E., Stepanić, V., Gurer-Orhan, H., & Saso, L. (2021) · Molecules · doi:10.3390/molecules26071853 · Cited by 50 · see citing works

p62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)–Curcumin Complex

Garufi, A., Giorno, E., Montani, M. S. G., Pistritto, G., Crispini, A., Cirone, M., & D’Orazi, G. (2021) · Biomolecules · doi:10.3390/biom11030348 · Cited by 50 · see citing works

The oncoprotein HBXIP competitively binds KEAP1 to activate NRF2 and enhance breast cancer cell growth and metastasis

Zhou, X., Zhu, C.-Y., Wu, Z., Guo, X., & Zou, W. (2019) · Oncogene · doi:10.1038/s41388-019-0698-5 · Cited by 50 · see citing works

Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells

Panieri, E., & Saso, L. (2021) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8146 · Cited by 46 · see citing works

Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) and genomic gain of the NQO1 locus modulates breast cancer cell sensitivity to quinones

Glorieux, C., Sandoval, J. M., Dejeans, N., Ameye, G., Poirel, H. A., Verrax, J., & Calderón, P. B. (2015) · Life Sciences · doi:10.1016/j.lfs.2015.12.017 · Cited by 46 · see citing works

Targeted Inhibition of Anti-Inflammatory Regulator Nrf2 Results in Breast Cancer Retardation In Vitro and In Vivo

Bovilla, V. R., Kuruburu, M. G., Bettada, V. G., Krishnamurthy, J., Sukocheva, O. A., Thimmulappa, R. K., Shivananju, N. S., Balakrishna, J. P., & Madhunapantula, S. V. (2021) · Biomedicines · doi:10.3390/biomedicines9091119 · Cited by 44 · see citing works

The antioxidative stress regulator Nrf2 potentiates radioresistance of oral squamous cell carcinoma accompanied with metabolic modulation

Matsuoka, Y., Yoshida, R., Kawahara, K., Sakata, J., Arita, H., Nkashima, H., Takahashi, N., Hirayama, M., Nagata, M., Hirosue, A., et al. (2022) · Laboratory Investigation · doi:10.1038/s41374-022-00776-w · Cited by 43 · see citing works

Curcumin induces p53-independent inactivation of Nrf2 during oxidative stress–induced apoptosis

Méndez-García, L., Castillo, M. M., Villegas‐Sepúlveda, N., Orozco, L., & Córdova, E. J. (2019) · Human & Experimental Toxicology · doi:10.1177/0960327119845035 · Cited by 41 · see citing works

Impact of nuclear factor erythroid-derived 2–like 2 and p62/sequestosome expression on prognosis of patients with gliomas

Zhao, M., Xu, H., Zhang, B., Hong, B., Yan, W. X., & Zhang, J. (2015) · Human Pathology · doi:10.1016/j.humpath.2015.02.009 · Cited by 38 · see citing works

Nrf2 inhibition sensitizes cholangiocarcinoma cells to cytotoxic and antiproliferative activities of chemotherapeutic agents

Samatiwat, P., Prawan, A., Senggunprai, L., Kukongviriyapan, U., & Kukongviriyapan, V. (2016) · Tumor Biology · doi:10.1007/s13277-016-5015-0 · Cited by 37 · see citing works

C/EBPβ/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis

Lei, K., Kang, S. S., Ahn, E. H., Chen, C., Liao, J., Liu, X., Li, H., Edgington‐Mitchell, L. E., Jin, L., & Ye, K. (2021) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-21-0019 · Cited by 32 · see citing works

TACC2 (transforming acidic coiled‐coil protein 2) in breast carcinoma as a potent prognostic predictor associated with cell proliferation

Onodera, Y., Takagi, K., Miki, Y., Takayama, K., Shibahara, Y., Watanabe, M., Ishida, T., Inoue, S., Sasano, H., & Suzuki, T. (2016) · Cancer Medicine · doi:10.1002/cam4.736 · Cited by 31 · see citing works

Overexpression of NRF 2 is correlated with prognoses of patients with malignancies: A meta‐analysis

Guo, Y., & Shen, L. (2017) · Thoracic Cancer · doi:10.1111/1759-7714.12462 · Cited by 29 · see citing works

The Roles of 4β-Hydroxywithanolide E from Physalis peruviana on the Nrf2-Anti-Oxidant System and the Cell Cycle in Breast Cancer Cells

Peng, C. Y., You, B., Lee, C.-L., Wu, Y., Lin, W., Lu, T., Chang, F.-C., & Lee, H. Z. (2016) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x16500348 · Cited by 29 · see citing works

Overexpression of ubiquitin-specific protease 2a (USP2a) and nuclear factor erythroid 2-related factor 2 (Nrf2) in human gliomas

Boustani, M. R., Khoshnood, R. J., Nikpasand, F., Taleshi, Z., Ahmadi, K., Yahaghi, E., & Goudarzi, P. K. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.03.003 · Cited by 27 · see citing works

NFR2/ABC transporter axis in drug resistance of breast cancer cells

Sargazi, Z., Yazdani, Y., Tahavvori, A., Youshanlouei, H. R., Alivirdiloo, V., Beilankouhi, E. A. V., & Valilo, M. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08384-7 · Cited by 26 · see citing works

Reduced mRNA expression levels of NFE2L2 are associated with poor outcome in breast cancer patients

Wolf, B., Goebel, G., Hackl, H., & Fiegl, H. (2016) · BMC Cancer · doi:10.1186/s12885-016-2840-x · Cited by 26 · see citing works

Competing endogenous RNA networks and ferroptosis in cancer: novel therapeutic targets

Orang, F. N., & Shadbad, M. A. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06732-4 · Cited by 22 · see citing works

Metformin diminishes the unfavourable impact of Nrf2 in breast cancer patients with type 2 diabetes

Urpilainen, E., Kangaskokko, J., Puistola, U., & Karihtala, P. (2019) · Tumor Biology · doi:10.1177/1010428318815413 · Cited by 18 · see citing works

PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2

Cheng, Y.-M., Lin, P.-L., Wu, D., Wang, L., Huang, C., & Lee, H. (2018) · Oncotarget · doi:10.18632/oncotarget.25254 · Cited by 17 · see citing works

Mutations and expression of the NFE2L2/KEAP1/CUL3 pathway in Chinese patients with lung squamous cell carcinoma

Zhang, Y., Fan, H. X., Fang, S., Wang, L., Chen, L., Jin, Y., Jiang, W., Lin, Z., Shi, Y., Zhan, C., et al. (2016) · Journal of Thoracic Disease · doi:10.21037/jtd.2016.06.08 · Cited by 16 · see citing works

Factors determining the sensitivity to proteasome inhibitors of multiple myeloma cells

Pelon, M., Krzemiński, P., Tracz‐Gaszewska, Z., & Misiewicz-Krzemińska, I. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1351565 · Cited by 15 · see citing works

High Expression of NRF2 and Low Expression of KEAP1 Predict Worse Survival in Patients With Operable Triple-Negative Breast Cancer

Lee, Y. S., Kang, J. K., Jung, E. S., & Lee, A. (2023) · Journal of Breast Cancer · doi:10.4048/jbc.2023.26.e42 · Cited by 15 · see citing works

Redox profile of breast tumor and associated adipose tissue in premenopausal women - Interplay between obesity and malignancy

Kalezic, A., Udicki, M., Srdić, B., Aleksic, M., Korać, A., Janković, A., & Korać, B. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101939 · Cited by 15 · see citing works

Correlation of NQO1 and Nrf2 in Female Genital Tract Cancer and Their Precancerous Lesions (Cervix, Endometrium and Ovary)

Osman, N., El-Maqsoud, N. M. R. A., & Gelany, S. E. (2015) · World Journal of Oncology · doi:10.14740/wjon931w · Cited by 14 · see citing works

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach

Revoredo, C. M. S., Pereira, R. D. O., Melo, M. D. A., Lopes‐Costa, P. V., Borges, P. D. T. M., Sousa, E. B., Neto, F. M., Campelo, V., Lopes, I. M. R. S., Barros-Oliveira, M. D. C., et al. (2020) · Oncotarget · doi:10.18632/oncotarget.27574 · Cited by 14 · see citing works

Combinatorial Implications of Nrf2 Inhibitors with FN3K Inhibitor: In vitro Breast Cancer Study

Beeraka, N. M., Zhang, J., Zhao, D., Liu, J., Chinnappa, A. U., Hemanth Vikram, P. R., Shivaprakash, P., Bannimath, N., Manogaran, P., Sinelnikov, M. Y., et al. (2023) · Current Pharmaceutical Design · doi:10.2174/0113816128261466231011114600 · Cited by 13 · see citing works

The prognostic value of NRF2 in solid tumor patients: a meta-analysis

Wang, L., Zhang, C., Qin, L., Xu, J., Li, X., Wang, W., Kong, L., Zhou, T., & Li, X. (2017) · Oncotarget · doi:10.18632/oncotarget.19838 · Cited by 12 · see citing works

New insights into evodiamine attenuates IPEC-J2 cells pyroptosis induced by T-2 toxin - Activating Keap1-Nrf2/NF-κB signaling pathway through binding with Keap1

Yu, T., Deng, X., Yang, X., Yin, Y., Liu, Y., & Xu, S. (2024) · Journal of Environmental Management · doi:10.1016/j.jenvman.2024.122605 · Cited by 10 · see citing works

Oxygen needs sulfur, sulfur needs oxygen: a relationship of interdependence

Sekine, H., Akaike, T., & Motohashi, H. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00464-7 · Cited by 10 · see citing works

Demystifying the management of cancer through smart nano-biomedicine via regulation of reactive oxygen species

Mishra, A. P., Kumar, R., Harilal, S., Nigam, M., Datta, D., Singh, S. K., Waranuch, N., & Chittasupho, C. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03469-x · Cited by 9 · see citing works

FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00586-6 · Cited by 9 · see citing works

The Role of Genetic Polymorphisms in Nrf2 and P73 in Egyptian Women with Breast Cancer

Azhary, N. M. A., Kamel, M. M., Ismail, Y. M., Mahmoud, A., & Radwan, E. M. (2016) · Europe PMC (PubMed Central) · doi:10.22034/apjcp.2016.17.11.4945 · Cited by 8 · see citing works

Selective inhibition of TGF-β-induced epithelial-mesenchymal transition overcomes chemotherapy resistance in high-risk lung squamous cell carcinoma

Sun, L., Wang, J., Yu, H., Zhu, X., Zhang, J., Hu, J., Yan, Y., Zhang, X., Zhu, Y., Jiang, G., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-07595-x · Cited by 7 · see citing works

Expression Patterns and Relevance of FN3K, Nrf2, and NQO1 in Breast Cancers

Beeraka, N. M., Zhang, J., Uthaiah, C. A., Anastasia, C. A., Liu, J., Vikram, P. R. H., Priyanka, M. K., Bannimath, N., Deka, R., Manogaran, P., et al. (2024) · Eurasian Journal of Medicine and Oncology · doi:10.14744/ejmo.2024.61033 · Cited by 7 · see citing works

Prognostic Worth of Nrf2/BACH1/HO-1 Protein Expression in the Development of Breast Cancer

Barnes, P., Agbo, E., Wang, J., Amoani, B., Opoku, Y. K., Okyere, P., & Saahene, R. O. (2023) · Medical Principles and Practice · doi:10.1159/000534534 · Cited by 6 · see citing works

Screening of Prognosis-Related Genes in Primary Breast Carcinoma Using Genomic Expression Data

Gu, Y., Chen, G., & Du, Y. (2019) · Journal of Computational Biology · doi:10.1089/cmb.2019.0131 · Cited by 4 · see citing works

Cancer metabolism in gastrointestinal cancer

Baba, H., Sawayama, H., & Miyanari, N. (2015) · Journal of Cancer Metastasis and Treatment · doi:10.4103/2394-4722.165533 · Cited by 3 · see citing works

Nrf2 and Inflammation-Triggered Carcinogenesis

Sarkar, S., Ghosh, N., Kundu, M., & Sil, P. C. (2020) · Progress in inflammation research · doi:10.1007/978-3-030-44599-7_6 · Cited by 2 · see citing works

Cooperation between oncogenic NRF2 and wild-type HRAS promotes progression of breast cancer

Kim, S., Saeidi, S., Cho, N., Lee, H., Han, W., Kim, K. P., & Surh, Y. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111920 · Cited by 1 · see citing works

NRF2 AND P73 POLYMORPHISMS IN EGYPTIAN WOMEN WITH BREAST CANCER

Hassan, I. A., Atia, H. A., El-Aziz, H. A. A., & Kamel, M. (2015) · Egyptian Journal of Biochemistry and Molecular Biology · doi:10.21608/ejb.2015.9838

Implications of NRF2 in Cancer Progression and Therapeutics

Agrawal, M., & Agrawal, S. K. (2022) · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects · doi:10.1007/978-981-16-1247-3_79-1

Implications of NRF2 in Cancer Progression and Therapeutics

Agrawal, M., & Agrawal, S. K. (2022) · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects · doi:10.1007/978-981-16-5422-0_79

Data from C/EBPβ/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis

Lei, K., Kang, S. S., Ahn, E. H., Chen, C., Liao, J., Liu, X., Li, H., Edgington‐Mitchell, L. E., Jin, L., & Ye, K. (2023) · doi:10.1158/1535-7163.c.6543378

NRF-2 and KEAP-1 Expression in Pancreatic Cancer Patients: A clinicopathological study

Fawzy, M., Sheta, H., Elkalla, H., & Yusuf, W. A. (2023) · International Journal of Cancer and Biomedical Research · doi:10.21608/jcbr.2023.230174.1312

Association Between Polymorphisms of NRF2 and Breast Cancer Risk in Japanese Population

Okano, Y., Kengo, U. S. U. I., Hanami, T., Taguri, M., Yamashita, T., & Miyagi, Y. (2024) · Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics · doi:10.3999/jscpt.55.2_67

Additional file 11 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720331

Additional file 9 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720325

Additional file 13 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720337

Additional file 3 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720307

Additional file 12 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720334

Additional file 6 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720316

Additional file 5 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720313

Additional file 2 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.25824842

Additional file 4 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720310

Additional file 8 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720322

Additional file 1 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.25824736

Additional file 10 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720328

Additional file 7 of FGFR2-triggered autophagy and activation of Nrf-2 reduce breast cancer cell response to anti-ER drugs

Gorska‐Arcisz, M., Popęda, M., Braun, M., Piasecka, D., Nowak, J. I., Kitowska, K., Stasiłojć, G., Okrój, M., Romańska, H., & Sądej, R. (2024) · Figshare · doi:10.6084/m9.figshare.26720319

Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism

Gambhir, L., Pokhriyal, A., Kapoor, N., & Kandwal, P. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-31698-2.00012-6

Subtype-Conditioned NRF2–KEAP1 Signaling in Breast Cancer: A Narrative Review and Hypothesis-Generating Framework from Chemoprevention to Therapy Resistance

Choi, H. Y., Kwon, H., & Hah, Y. (2026) · Antioxidants · doi:10.3390/antiox15101223

NRF2 in human breast cancer patients as a good prognostic factor.

Yu, X. F., & Jiang, H. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2015.33.15_suppl.e12570

The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis

Almeida, M., Soares, M., Ramalhinho, A. C., Fonseca-Moutinho, J. A., Breitenfeld, L., & Pereira, L. C. (2019) · Breast Cancer Research and Treatment · doi:10.1007/s10549-019-05494-4 · Cited by 57 · see citing works

Abstract 646: The amount of NRF2 expression in bulk tumors involves immune cells as well as cancer cells, which is associated with better prognosis in ER-positive/HER2-negative breast cancer

Oshi, M., Le, L. M., Angarita, F. A., Tokumaru, Y., Li, Y., Matsuyama, R., Endo, I., & Takabe, K. (2021) · Cancer Research · doi:10.1158/1538-7445.am2021-646

NRF2 drives an oxidative stress response predictive of breast cancer

Wolowczyk, C., Neckmann, U., Aure, M. R. R., Hall, M., Johannessen, B., Zhao, S., Skotheim, R. I., Andersen, S. B., Zwiggelaar, R. T., Steigedal, T. S., et al. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.03.029 · Cited by 20 · see citing works

NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction

Zhang, C., Wang, H.-J., Bao, Q., Wang, L., Guo, T.-K., Chen, W., Xu, L., Zhou, H.-S., Bian, J., Yang, Y., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.12435 · Cited by 127 · see citing works