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Cited by 779

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Regulation of ovarian function: the role of anti-Mullerian hormone

Open access
Durlinger, A L, Visser, J A, Themmen, A P·2002·Reproduction

Abstract

Anti-Mullerian hormone (AMH), also known as Mullerian inhibiting substance, is a member of the transforming growth factor β superfamily of growth and differentiation factors. In contrast to other members of the family, which exert a broad range of functions in multiple tissues, the principal function of AMH is to induce regression of the Mullerian ducts during male sex differentiation. However, the patterns of expression of AMH and its type II receptor in the postnatal ovary indicate that AMH may play an important role in ovarian folliculogenesis. This review describes several in vivo and in vitro studies showing that AMH participates in two critical selection points of follicle development: it inhibits the recruitment of primordial follicles into the pool of growing follicles and also decreases the responsiveness of growing follicles to FSH.

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Metadata

Authors
Durlinger, A. L., Visser, J. A., & Themmen, A. P.
Venue
Reproduction
Published
2002-11-01
Volume
124
Issue
5
Pages
601-609
ISSN
  • 1470-1626 (ISSN-L)
  • 1741-7899
OpenAlex
W2160864692
Cited by
779
References
1
FWCI
12.38
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Regulation of ovarian function: the role of anti-Mullerian hormone. https://app.cochat.ai/papers/10.1530/rep.0.1240601
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Durlinger, A. L., Visser, J. A., & Themmen, A. P. (2002). Regulation of ovarian function: the role of anti-Mullerian hormone. Reproduction. https://doi.org/10.1530/rep.0.1240601

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.