A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila

Zhang, Sheng, Binari, Richard, Zhou, Rui, Perrimon, Norbert·2010·Genetics
DOI 10.1534/genetics.109.112516

Cited by (157)

Items 101–157 of 157

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  8. Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster
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  9. Comparative analysis of the intracellular responses to disease-related aggregation-prone proteins
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  10. Functional and systems biology approaches to Huntington's disease
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  11. PolyQ-Expansion Causes Mitochondria Fragmentation Independent of Huntingtin and Is Distinct from Traumatic Brain Injury (TBI)/Mechanical Stress-Mediated Fragmentation Which Results from Cell Death
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  12. HSP90 et al.: Chaperome and Proteostasis Deregulation in Human Disease
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  13. Connecting Circadian Genes to Neurodegenerative Pathways in Fruit Flies
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  14. Analyzing the Structure, Function and Information Flow in Signaling Networks using Quantitative Cellular Signatures
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  15. Synthetic Lethality Induced by a Strong Drosophila Enhancer of Expanded Polyglutamine Tract
    Ping Zhang, Qiming Wang, Hannah Q. Hughes, Gino Intrieri · 2014 · Open Journal of Genetics
  16. The white gene controls copulation success in Drosophila melanogaster
    Chengfeng Xiao, Shuang Qiu, R. Meldrum Robertson · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
  17. MeDUsA: A novel system for automated axon quantification to evaluate neuroaxonal degeneration
    Yohei Nitta, Hiroki Kawai, Jiro Osaka, Satoko Hakeda‐Suzuki, Yoshitaka Nagai, Karolína Doubková, Takashi Suzuki, Gaia Tavosanis, Atsushi Sugie · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  18. The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
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  19. The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
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  21. Ubiquitin ligase Nedd4 regulates the abundance and toxicity of mutant huntingtin
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  22. Modeling Huntington Disease in Yeast and Invertebrates
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  24. Unbiased genome-wide approaches to identify vulnerability factors in Huntington's disease
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  25. Drosophila en el estudio de las interacciones proteicas de hTBP en el desarrollo y modelaje de SCA17
    Rubén J. Montalvo-Méndez, Marcela Cárdenas‐Tueme, Diana Reséndez‐Pérez · 2024 · Gaceta Médica de México
  26. Animal Models for Huntington's and Parkinson's Diseases
    Meera T. Saxena · 2013 · Materials and Methods
  27. Drosophila in the study of hTBP protein interactions in the development and modeling of SCA17
    Rubén J. Montalvo-Méndez, Marcela Cárdenas‐Tueme, Diana Reséndez‐Pérez · 2024 · Gaceta Médica de México
  28. Atypical Domain Communication and Domain Functions of a Hsp110 Chaperone
    Vignesh Kumar, Joshua Jebakumar Peter, Amin Sagar, Arjun Ray, Ashish, Koyeli Mapa · 2018 · SSRN Electronic Journal
  29. Glutamine Synthetase-1 induces autophagy-lysosomal degradation of huntingtin aggregates and ameliorates animal motility in a Drosophila model for Huntington’s disease
    Luisa Vernizzi, Chiara Paiardi, Giusimaria Licata, Teresa Vitali, Stefania Santarelli, Martino Raneli, Vera Manelli, Manuela Rizzetto, Mariarosa Gioria, Maria E. Pasini et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Enhanced methods for genetic assays in Drosophila cells
    Y Wang, JY Lee, Amy Housden, Emma Hottinger, Benjamin E. Housden · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  31. Dikar-Induced Synthetic Lethality in a Drosophila Model of CAG Repeat Diseases Does Not Result from an Expression Feedback Loop
    Daniel F. Camacho · 2013 · OpenCommons - UConn (University of Connecticut)
  32. Synthetic Lethality Induced by Toxic Polyglutamine Tract II: A Survey in Drosophila
    Ping Zhang, Daniel F. Camacho, Shashank Vodapally, Shanado Williams, Kavitha Kannan · 2015 · Open Journal of Genetics
  33. A Genome-Wide RNAi Screen for Modifiers of Polyglutamine-Induced Neurotoxicity in Drosophila
    Hannes Voßfeldt · 2013 · eDiss (Georg-August-Universität Göttingen)
  34. STUDYING AGGREGATE FORMATION BY AMYOTROPHIC LATERAL SCLEROSIS-ASSOCIATED MUTANT SOD1 PROTEIN IN DROSOPHILA MODEL
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  35. 6 Huntington’s Disease and Stem Cells
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  36. The ubiquitin proteasome system in Huntington disease : impairment of the proteolytic machinery aggravates huntingtin aggregation and toxicity
    Remko de Pril · 2011
  37. Image informatics for studying signal transduction in cells interacting with 3D matrices
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  38. Functional Analysis of Cytosolic Hsp70 Nucleotide Exchange Factor Networks in Yeast
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  39. Hunting for the mutant without the MAP(K)
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  40. Understanding Huntington's disease using Machine Learning Approaches
    Sonali Lokhande · 2017 · Scholarship - Claremont (Claremont Colleges)
  41. Step I: Target Identification
    Pierfausto Seneci · 2018 · Elsevier eBooks
  42. Modelling of human polyglutamine neurological disorders in Drosophila
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  44. Genome Sequencing in Field Crops: Unlocking Agricultural Potential
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  45. The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
    Liam C. Hunt, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth Pagala, Junmin Peng, Fabio Demontis · 2024 · eLife
  46. Author response: The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
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  47. eLife Assessment: The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
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  48. The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
    Liam C. Hunt, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth Pagala, Junmin Peng, Fabio Demontis · 2024 · eLife
  49. Reviewer #1 (Public Review): The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
    2024 · eLife
  50. Reviewer #2 (Public Review): The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
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  51. Reviewer #3 (Public Review): The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging
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  52. Insect Cell Lines and RNAi
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  53. Regulation of huntingtin-polyQ aggregation by glucose transporters and saccharide-binding receptors during aging in Drosophila
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  54. EDTP Loss of Function Impairs Longevity and Reproduction
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  55. Nervous system integrity in Drosophila : essential and dosage-sensitive roles of Hsp110
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  56. BindingDB Entry 50012342: GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes.
    BindingDB · 2022 · UC San Diego
  57. Interrogating the role of splicing factors in Huntington’s Disease
    Gurdeep S. Kooner · 2015 · Leicester Research Archive (University of Leicester)