Overview of Epidemiology, Clinical Features, Genetics, Neurobiology, and Prognosis of Adolescent Attention-Deficit/Hyperactivity Disorder
Abstract
ADHD is a common neurobehavioral disorder that is highly heritable. Recent research has identified several genes that are associated with ADHD. In addition, there are several biological factors that are environmentally derived that appear to play a role in the etiology of ADHD. It is quite clear that ADHD begins in childhood, but persists into adolescence and adulthood for the majority of individuals. Since the criteria for the diagnosis of ADHD are most applicable to children, making the diagnosis in adolescents requires an understanding of how these symptoms are expressed in this age group. The prognosis of ADHD is variable and depends on several psychosocial factors, with approximately 20% of adolescents who perform well in social, emotional, and educational domains, another 20% who perform poorly in these domains, and the majority who perform somewhere in the middle.
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There are well-established functional impairments and poor life outcomes in adolescents with ADHD.
“Despite the relatively high level of perceived QOL among most current study participants, there are well-established functional impairments and poor life outcomes seen in adolescents with ADHD (Schubiner and Katragadda 2008).”
From Participant-Perceived Quality of Life in a Long-Term, Open-Label Trial of Lisdexamfetamine Dimesylate in Adolescents with Attention-Deficit/Hyperactivity Disorder (2014) · cites this paper as Schubiner and Katragadda 2008
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Findling, R. L., Childress, A. C., Cutler, A. J., Gasior, M., Hamdani, M., Ferreira-Cornwell, M. C., & Squires, L. (2011) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2011.01.007 · Cited by 120 · see citing works
Weisler, R., Childress, A., Adler, L., Kollins, S., Goodman, D., Hamdani, & Dirks, B. (2013) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s47087 · Cited by 16 · see citing works
Childress, A. C., Cutler, A. J., Saylor, K., Gasior, M., Hamdani, M., Ferreira-Cornwell, M. C., & Findling, R. L. (2014) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2013.0077 · Cited by 5 · see citing works
- Authors
- Schubiner, H., & Katragadda, S.
- Affiliations
- Wayne State University (US)
- Dartmouth College (US)
- ORCID
- Schubiner, Howard
- Venue
- AM:STARs: ADHD/Learning Disorders, Vol. 19, No. 2
- Publisher
- American Academy of Pediatrics
- Published
- 2008-08-01
- Volume
- 19
- Issue
- 2
- Pages
- 209-215
- OpenAlex
- W2417517396
- Cited by
- 21
- References
- 0
- Citations by year
- 2025: 1 · 2024: 1 · 2018: 2 · 2017: 1 · 2014: 3 · 2013: 1
- FWCI
- 16.44
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- American Academy of Pediatrics eBooks (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Keywords
- ADHD epidemiology, ADHD genetics, ADHD etiology, environmental risk factors, psychosocial factors, neurobiology of ADHD
- MeSH terms
- Adolescent, Attention Deficit Disorder with Hyperactivity, Humans, Prognosis, Genetic Predisposition to Disease, Diagnostic and Statistical Manual of Mental Disorders
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