Postnatal glucose homeostasis in late-preterm and term infants
Abstract
This report provides a practical guide and algorithm for the screening and subsequent management of neonatal hypoglycemia. Current evidence does not support a specific concentration of glucose that can discriminate normal from abnormal or can potentially result in acute or chronic irreversible neurologic damage. Early identification of the at-risk infant and institution of prophylactic measures to prevent neonatal hypoglycemia are recommended as a pragmatic approach despite the absence of a consistent definition of hypoglycemia in the literature.
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Published guidelines for screening at-risk newborns and managing low plasma glucose concentrations in neonates focus on the immediate neonatal period but do not address the diagnosis and management of disorders causing recurrent and prolonged hypoglycemia.
“Published guidelines for screening at-risk newborns and managing low PG concentrations in neonates focus on the immediate neonatal period, but do not address the diagnosis and management of disorders causing recurrent and prolonged hypoglycemia.4–6”
From Recommendations from the Pediatric Endocrine Society for evaluation and management of persistent hypoglycemia in neonates, infants, and children (2015) · cites this paper as [5]
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- Authors
- Adamkin, D. H., & Committee on Fetus and Newborn
- Corresponding author
- Adamkin, David H.
- ORCID
- Adamkin, David H.
- Venue
- PEDIATRICS
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2011-03-01
- Volume
- 127
- Issue
- 3
- Pages
- 575-9
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2107321972
- Cited by
- 771
- References
- 32
- Citations by year
- 2026: 39 · 2025: 42 · 2024: 56 · 2023: 59 · 2022: 67 · 2021: 73 · 2020: 82 · 2019: 50 · 2018: 64 · 2017: 49 · 2016: 48 · 2015: 39 · 2014: 39 · 2013: 32 · 2012: 23
- FWCI
- 4.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal Health and Biochemistry
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Neonatal and fetal brain pathology
- Keywords
- neonatal hypoglycemia, glucose homeostasis, late preterm infants, term infants, hypoglycemia screening, hypoglycemia management, prophylaxis, neurologic damage, hypoglycemia definition
- MeSH terms
- Blood Glucose, Homeostasis, Humans, Hypoglycemia, Infant, Newborn, Infant, Premature, Diseases
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