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Cited by 135Complementary and Alternative Medicine StudiesAutism Spectrum Disorder ResearchChild Nutrition and Feeding Issues

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Complementary and Alternative Medicine Use in a Large Pediatric Autism Sample

Perrin, James M., Coury, Daniel L., Hyman, Susan L., Cole, Lynn, Reynolds, Ann M., Clemons, Traci·2012·PEDIATRICS
DOI 10.1542/peds.2012-0900e
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Abstract

BACKGROUND AND OBJECTIVE: Children and adolescents with autism spectrum disorder (ASD) often use complementary and alternative medicine (CAM), usually along with other medical care. This study aimed to determine associations of ASD diagnostic category, co-existing conditions, and use of medications with use of CAM. METHODS: We used the Autism Speaks Autism Treatment Network patient registry, which collects information on CAM use, medical conditions, and psychotropic medication at enrollment. CAM was categorized as special diets versus "other" CAM; ASD was defined as autism, pervasive developmental disorder (PDD), or Asperger's. Gastrointestinal symptoms, seizure disorders, sleep problems, and medication use were determined from parent report. Child Behavior Checklist (CBCL) scores were used to measure behavioral symptoms. Logistic regression was used to determine associations of diagnostic category, other medical conditions, and medication use with CAM treatments, controlling for demographic characteristics. RESULTS: Of 3413 subjects in the registry as of April 2011, 3173 had complete data on CAM use: 896 (28%) reported any use; 548 (17%), special diets; and 643 (20%), other CAM. Higher rates of CAM use were associated with gastrointestinal symptoms (odds ratio [OR] = 1.88), seizures (OR = 1.58), and CBCL total score >70 (OR = 1.29). Children with PDD (OR = 0.62), Asperger's (OR = 0.66), or using medications (0.69) had lower rates. CONCLUSIONS: Children with ASD use more CAM when they have co-existing gastrointestinal symptoms, seizure disorders, and behavior problems. This study suggests the importance of asking about CAM use in children with ASD, especially those with complex symptoms.

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  1. Barnes, 2007, Natl Health, Stat Report, 2008, :1–23

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Metadata

Authors
Perrin, J. M., Coury, D. L., Hyman, S. L., Cole, L., Reynolds, A. M., & Clemons, T.
Affiliations
  • Harvard University (US)
  • Nationwide Children's Hospital (US)
  • University of Rochester Medicine (US)
  • Children's Hospital Colorado (US)
  • Emmes (United States) (US)
ORCID
Venue
PEDIATRICS
Publisher
American Academy of Pediatrics (AAP)
Published
2012-11-01
Volume
130
Issue
Supplement_2
Pages
S77-S82
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.2012-0900e
OpenAlex
W2111403994
Cited by
135
References
12
Citations by year
2026: 4 · 2025: 6 · 2024: 3 · 2023: 9 · 2022: 10 · 2021: 13 · 2020: 8 · 2019: 13 · 2018: 13 · 2017: 13 · 2016: 11 · 2015: 13 · 2014: 11 · 2013: 8
FWCI
24.95
Type
journal article
Language
en
Open access
closed
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
Keywords
complementary and alternative medicine, autism spectrum disorder, pervasive developmental disorders, Asperger syndrome, special diets, gastrointestinal symptoms, epilepsy, psychotropic drugs, behavioral problems
MeSH terms
Adolescent, Complementary Therapies, Autistic Disorder, Child, Child, Preschool, Cross-Sectional Studies, Female, Humans, Male

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