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Cited by 82Maternal and Neonatal HealthcareInfant Development and Preterm CareMaternal Mental Health During Pregnancy and Postpartum

Prenatal and Infancy Nurse Home Visiting and 18-Year Outcomes of a Randomized Trial

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Kitzman, Harriet, Olds, David L., Knudtson, Michael D., Cole, Robert, Anson, Elizabeth, Smith, Joyce A., Fishbein, Diana, DiClemente, Ralph +5 more·2019·Pediatrics
DOI 10.1542/peds.2018-3876PMC PMC6889968
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Abstract

OBJECTIVES: Given earlier effects found in randomized clinical trials of the Nurse-Family Partnership, we examined whether this program would improve 18-year-old first-born youths' cognition, academic achievement, and behavior and whether effects on cognitive-related outcomes would be greater for youth born to mothers with limited psychological resources (LPR) and on arrests and convictions among females. METHODS: We enrolled 742 pregnant, low-income women with no previous live births and randomly assigned them to receive either free transportation for prenatal care plus child development screening and referral (control; n = 514) or prenatal and infant home nurse visit (NV) plus transportation and screening (n = 228). Assessments were completed on 629 18-year-old first-born offspring to evaluate these primary outcomes: (1) cognitive-related abilities (nonverbal intelligence, receptive language, and math achievement) and (2) behavioral health (internalizing behavioral problems, substance use and abuse, sexually transmitted infections, HIV risk, arrests, convictions, and gang membership). RESULTS: Compared with control-group counterparts, NV youth born to mothers with LPR had better receptive language (effect size = 0.24; 95% confidence interval [CI]: 0.00 to 0.47; P = .05), math achievement (effect size = 0.38; 95% CI: 0.14 to 0.61; P = .002), and a number of secondary cognitive-related outcomes. NV females, as a trend, had fewer convictions (incidence ratio = 0.47; 95% CI: 0.20 to 1.11; P = .08). There were no intervention effects on other behaviors. CONCLUSIONS: The program improved the cognitive-related skills of 18-year-olds born to mothers with LPR and, as a trend, reduced female convictions but produced no other effects on youth behavioral health.

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  • The Nurse-Family Partnership has been rigorously studied and reproduced in multiple regions across the United States with over a decade of participant follow-up.

    “The Nurse-Family Partnership, in which a nurse attended multiple in-home visits to low-income, first-time pregnant mothers, has been rigorously studied and reproduced in multiple regions across the United States with over a decade of participant follow-up.30,32,33”

    From Community investment interventions as a means for decarceration: A scoping review (2022) · cites this paper as [30]

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Authors
Kitzman, H., Olds, D. L., Knudtson, M. D., Cole, R., Anson, E., Smith, J. A., Fishbein, D., DiClemente, R., Wingood, G., Caliendo, A. M., Hopfer, C., Miller, T., & Conti, G.
Affiliations
  • University of Rochester Medicine (US)
  • Departments of Pediatrics and
  • Pennsylvania State University (US)
  • New York University (US)
  • Columbia University (US)
  • Brown University (US)
  • University of Colorado Anschutz (US)
  • Curtin University (AU)
  • University College London (GB)
ORCID
Venue
Pediatrics
Publisher
American Academy of Pediatrics (AAP)
Published
2019-12-01
Volume
144
Issue
6
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.2018-3876
PMC
PMC6889968
OpenAlex
W2991420758
Cited by
82
References
3
Citations by year
2026: 3 · 2025: 16 · 2024: 15 · 2023: 11 · 2022: 14 · 2021: 14 · 2020: 7 · 2019: 2
FWCI
12.60
Type
journal article
Language
en
Open access
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
  • Economic and Social Research Council (ES/M001660/1)
  • National Institute on Drug Abuse (R01DA021624)
Topics
  • Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords
Nurse-Family Partnership, nurse home visiting, prenatal care, low-income pregnant women, firstborn children, cognitive outcomes, academic performance, receptive language, mathematics achievement, internalizing problems, substance use, young women, developmental screening
MeSH terms
Health Risk Behaviors, Adolescent, Cognition, Female, Follow-Up Studies, Home Care Services, House Calls, Humans, Infant, Infant, Newborn, Male, Poverty, Pregnancy, Prenatal Care, Time Factors, Treatment Outcome, Young Adult, Nurses, Community Health

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