The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Gold nanoparticles for molecular diagnostics
Abstract
Gold nanoparticles (AuNPs) exhibit a unique phenomenon, known as surface plasmon resonance, which is responsible for their large absorption and scattering cross-sections, which are four to five orders of magnitude larger than those of conventional dyes. In addition, their optical properties can be controlled by varying their sizes, shapes and compositions. AuNPs can be easily synthesized and functionalized with different biomolecules including oligonucleotides. Numerous methods have been utilized for detecting AuNPs such as colorimetric, scanometric, fluorescence, surface-enhanced Raman scattering and electrochemical techniques. These unique aspects have permitted the development of novel AuNP-based assays for molecular diagnostics which promise increased sensitivity and specificity, multiplexing capability, and short turnaround times. AuNP-based colorimetric assays in particular show great potential in point-of-care testing assays. This review discusses properties of AuNPs and their utilization for the development of novel molecular assays.
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Cites
Nanostructures in Biodiagnostics
Rosi, N. L., & Mirkin, C. A. (2005) · Chemical Reviews · doi:10.1021/cr030067f · Cited by 4,603
Cited by
Gold Nanoparticles in Chemical and Biological Sensing
Saha, K., Agasti, S. S., Kim, C., Li, X., & Rotello, V. M. (2012) · Chemical Reviews · doi:10.1021/cr2001178 · Cited by 4,620
Plasmons in Strongly Coupled Metallic Nanostructures
Halas, N. J., Lal, S., Chang, W.-S., Link, S., & Nordlander, P. (2011) · Chemical Reviews · doi:10.1021/cr200061k · Cited by 3,135
Saratale, R. G., Karuppusamy, I., Saratale, G. D., Pugazhendhi, A., Kumar, G., Park, Y., Ghodake, G. S., Bharagava, R. N., Banu, J. R., & Shin, H. S. (2018) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2018.05.045 · Cited by 388
Colorimetric Detection of Heavy Metal Ions Using Label-Free Gold Nanoparticles and Alkanethiols
Hung, Y.-L., Hsiung, T.-M., Chen, Y.-Y., Huang, Y.-F., & Huang, C.-C. (2010) · The Journal of Physical Chemistry C · doi:10.1021/jp1061573 · Cited by 258
Formation, antimicrobial activity, and biomedical performance of plant-based nanoparticles: a review
Nguyen, N. T. T., Nguyen, L. M., Nguyen, T. T. T., Nguyen, T. T., Nguyen, D. T. C., & Tran, T. V. (2022) · Environmental Chemistry Letters · doi:10.1007/s10311-022-01425-w · Cited by 175
Metadata
- Authors
- Radwan, S. H., & Azzazy, H. M.
- Venue
- Expert Review of Molecular Diagnostics
- Publisher
- Informa UK Limited
- Published
- 2009-07
- Volume
- 9
- Issue
- 5
- Pages
- 511-524
- ISSN
- 1473-7159 (ISSN-L)
- 1744-8352
- OpenAlex
- W2020881911
- Cited by
- 161
- References
- 1
- FWCI
- 6.57
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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