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The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

History of cannabis as a medicine: a review

Open access
Zuardi, Antonio Waldo·2006·Revista Brasileira de Psiquiatria

Abstract

Cannabis as a medicine was used before the Christian era in Asia, mainly in India. The introduction of cannabis in the Western medicine occurred in the midst of the 19th century, reaching the climax in the last decade of that century, with the availability and usage of cannabis extracts or tinctures. In the first decades of the 20th century, the Western medical use of cannabis significantly decreased largely due to difficulties to obtain consistent results from batches of plant material of different potencies. The identification of the chemical structure of cannabis components and the possibility of obtaining its pure constituents were related to a significant increase in scientific interest in such plant, since 1965. This interest was renewed in the 1990's with the description of cannabinoid receptors and the identification of an endogenous cannabinoid system in the brain. A new and more consistent cycle of the use of cannabis derivatives as medication begins, since treatment effectiveness and safety started to be scientifically proven.

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Metadata

Authors
Zuardi, A. W.
Venue
Revista Brasileira de Psiquiatria
Published
2006-06
Volume
28
Issue
2
Pages
153-157
ISSN
1516-4446 (ISSN-L)
OpenAlex
W1966709829
Cited by
730
References
19
FWCI
3.58
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: History of cannabis as a medicine: a review. https://app.cochat.ai/papers/10.1590/s1516-44462006000200015
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Zuardi, A. W. (2006). History of cannabis as a medicine: a review. Revista Brasileira de Psiquiatria. https://doi.org/10.1590/s1516-44462006000200015

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.