Prophylactic effect of coconut water (Cocos nucifera L.) on ethylene glycol induced nephrocalcinosis in male wistar rat
Open accessAbstract
INTRODUCTION: In some occasions, correlations between human structures can help planning surgical intra-abdominal interventions. The previous determination of ureteral length helps pre-operatory planning of surgeries, reduces costs of auxiliary exams, the correct choice of double-J catheter with low morbidity and fewer symptoms, and an adequate adhesion to treatment. OBJECTIVE: To evaluate ureteral length in adult cadavers and to analyze its correlation with anthropometric measures. MATERIALS AND METHODS: From April 2009 to January 2012 we determined ureteral length of adult cadavers submitted to necropsy and obtained the following measures: height, distance from shoulder to wrist, elbow-wrist, xiphoid appendix-umbilicus, umbilicus-pubis, xiphoid appendix-pubis and between iliac spines. We analyzed the correlations between ureteral length and those anthropometric measures. RESULTS: We dissected 115 ureters from 115 adult corpses from April 2009 to January 2012. Median ureteral length didn't vary between sexes or according to height. It was observed no correlation among ureteral length and all considered anthropometric measures in all analyzed subgroups and in general population. There were no significant differences between right and left ureteral measures. CONCLUSIONS: There is no difference of ureteral length in relation to height or gender (male or female). There is no significant correlation among ureteral length and the considered anthropometric measures.
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A recent anti-urolithiatic study involving male Wistar rats proved that CW prevented the adherence of crystals on renal tissues and reduced the number of crystals formed in the urine.
“A recent anti-urolithiatic study involving male Wistar rats proved that CW prevented the adherence of crystals on renal tissues and reduced the number of crystals formed in the urine [38].”
From Research Progress in Coconut Water: A Review of Nutritional Composition, Biological Activities, and Novel Processing Technologies (2025) · cites this paper as [38]
The Results report markedly fewer urinary crystals and no crystalline deposits in renal tissue among coconut-water-treated male Wistar rats. The paper did not test crystal adherence as a mechanism, and its discussion acknowledges limitations and describes the findings as suggesting a beneficial effect; “proved” overstates that conclusion. Page numbers are unavailable in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measuredCoconut water had prophylactic action against nephrolithiasis in a Wistar rat model.
“Coconut water had prophylactic action against nephrolithiasis in an experiment with a Wistar rat model (64).”
From Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review (2015) · cites this paper as [64]
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References 31 · Cited by 60
Research works printed but not linked: 4
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- Authors
- Gandhi, M., Aggarwal, M., Puri, S., & Singla, S. K.
- Affiliations
- Panjab University (IN)
- ORCID
- Venue
- International braz j urol
- Publisher
- FapUNIFESP (SciELO)
- Published
- 2013-01
- Volume
- 39
- Issue
- 1
- Pages
- 108-117
- ISSN
- 1677-5538 (ISSN-L)
- OpenAlex
- W2114333753
- Cited by
- 60
- References
- 31
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 9 · 2020: 6 · 2019: 3 · 2018: 11 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 2
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- International braz j urol (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Indian Council of Medical Research
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Kidney Stones and Urolithiasis Treatments
- Physical Sciences › Chemistry › Inorganic Chemistry › Coconut Research and Applications
- Health Sciences › Medicine › Obstetrics and Gynecology › Ureteral procedures and complications
- Keywords
- coconut water, Cocos nucifera, nephrocalcinosis, ethylene glycol, ureteral length, anthropometric measures, cadaveric dissection, surgical planning
- MeSH terms
- Animals, Cocos, Creatinine, Kidney, Male, Phytotherapy, Nephrocalcinosis, Random Allocation, Urea, Water, Treatment Outcome, Rats, Wistar, Ethylene Glycol, Rats, Urolithiasis, Real-Time Polymerase Chain Reaction
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