The DOI matches its Crossref record.
Isolation and Characterization of Neural Stem Cells from the Adult Human Olfactory Bulb
Abstract
We have recently isolated stem cells deriving from the olfactory bulbs of adult patients undergoing particularly invasive neurosurgery. After improving our experimental conditions, we have now obtained neural stem cells according to clonal analysis. The cells can be expanded, established in continuous cell lines and differentiated into the three classical neuronal phenotypes (neurons, astrocytes, and oligodendrocytes). Also, after exposition to leukemia inhibitory factor, we are able to improve the number of neurons, an ideal biological source for transplantation in various neurodegenerative disorders.
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Citations
Cited by
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration
Sanai, N., Tramontin, A. D., Quiñones-Hinojosa, A., Barbaro, N. M., Gupta, N., Kunwar, S., Lawton, M. T., McDermott, M. W., Parsa, A. T., Manuel-García Verdugo, J., et al. (2004) · Nature · doi:10.1038/nature02301 · Cited by 1,313
The Biology of Cancer Stem Cells
Lobo, N. A., Shimono, Y., Qian, D., & Clarke, M. F. (2007) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.22.010305.104154 · Cited by 1,043
Enwere, E., Shingo, T., Gregg, C., Fujikawa, H., Ohta, S., & Weiss, S. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.2751-04.2004 · Cited by 549
Adult neurogenesis and neural stem cells of the central nervous system in mammals
Taupin, P., & Gage, F. H. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10378 · Cited by 527
The neuropoietic cytokine family in development, plasticity, disease and injury
Bauer, S., Kerr, B. J., & Patterson, P. H. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2054 · Cited by 419
Metadata
- Authors
- Pagano, S. F., Impagnatiello, F., Girelli, M., Cova, L., Grioni, E., Onofri, M., Cavallaro, M., Etteri, S., Vitello, F., Giombini, S., Solero, C. L., & Parati, E. A.
- Venue
- STEM CELLS
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-07
- Volume
- 18
- Issue
- 4
- Pages
- 295-300
- ISSN
- 1066-5099 (ISSN-L)
- 1549-4918
- OpenAlex
- W2039945427
- Cited by
- 225
- References
- 0
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Isolation and Characterization of Neural Stem Cells from the Adult Human Olfactory Bulb. https://app.cochat.ai/papers/10.1634/stemcells.18-4-295
- The paper
- Pagano, S. F., Impagnatiello, F., Girelli, M., Cova, L., Grioni, E., Onofri, M., Cavallaro, M., Etteri, S., Vitello, F., Giombini, S., Solero, C. L., & Parati, E. A. (2000). Isolation and Characterization of Neural Stem Cells from the Adult Human Olfactory Bulb. STEM CELLS. https://doi.org/10.1634/stemcells.18-4-295
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
