DNA polymerases and human diseases

Cites (273)

Items 201–273 of 273

1. Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase ι
   Robert E. Johnson, Louise Prakash, Satya Prakash · 2005 · Proceedings of the National Academy of Sciences
2. Functions of Eukaryotic DNA Polymerases
   Polina V. Shcherbakova, Katarzyna Bębenek, Thomas A. Kunkel · 2003 · Science of Aging Knowledge Environment
3. A Conserved Region in the Amino Terminus of DNA Polymerase δ Is Involved in Proliferating Cell Nuclear Antigen Binding
   Shan-Jian Zhang, Xiaorong Zeng, Peng Zhang, Ngoc Toomey, Ray-Yuan Chuang, Long‐Sheng Chang, Marietta Lee · 1995 · Journal of Biological Chemistry
4. Investigation of the Possible Role of a Novel Gene, DPCD , in Primary Ciliary Dyskinesia
   Maimoona A. Zariwala, Wanda K. O’Neal, Peadar G. Noone, Margaret W. Leigh, Michael R. Knowles, Lawrence E. Ostrowski · 2003 · American Journal of Respiratory Cell and Molecular Biology
5. Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene.
   Dominic W. Chung, J A Zhang, C K Tan, Earl W. Davie, Antero G. So, Kathleen M. Downey · 1991 · Proceedings of the National Academy of Sciences
6. Prostate-Cancer-Associated I260M Variant of DNA Polymerase β Is a Sequence-Specific Mutator
   Shibani Dalal, Suzanne E. Hile, Kristin A. Eckert, Ka-Wai Sun, Daniela Starcevic, Joann Balazs Sweasy · 2005 · Biochemistry
7. A novel family of DNA-polymerase-associated B subunits
   Minna Mäkiniemi, Helmut Pospiech, Seppo H. Kilpeläinen, Maarit Jokela, Mauno Vihinen, Juhani Eerik Syväoja · 1999 · Trends in Biochemical Sciences
8. Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta.
   Marilyn Diaz, Nicholas B. Watson, Gene Turkington, Laurent K. Verkoczy, Norman R. Klinman, W. Glenn McGregor · 2003 · PubMed
9. Reconstitution and Characterization of the Human DNA Polymerase Delta Four-Subunit Holoenzyme
   Bin Xie, Nayef A. Mazloum, Li Liu, Amal A. Rahmeh, Hao Li, Marietta Lee · 2002 · Biochemistry
10. Localization of the Deoxyribose Phosphate Lyase Active Site in Human DNA Polymerase ι by Controlled Proteolysis
    Rajendra Prasad, Katarzyna Bębenek, Esther W. Hou, David D. Shock, William A. Beard, Roger Woodgate, Thomas A. Kunkel, Samuel H. Wilson · 2003 · Journal of Biological Chemistry
11. Functional mutation of DNA polymerase β found in human gastric cancer – inability of the base excision repair in vitro
    章成 岩永, Mamoru Ouchida, Kohji Miyazaki, Katsuji Hori, Tsunehiro Mukai · 1999 · Mutation Research/DNA Repair
12. Localisation of human DNA polymerase κ to replication foci
    Valérie Bergoglio, Clarisse Bavoux, Vincent H. M. Verbiest, Jean‐Sébastien Hoffmann, Christophe Cazaux · 2002 · Journal of Cell Science
13. Telomere Repeat Binding Factor 2 Interacts with Base Excision Repair Proteins and Stimulates DNA Synthesis by DNA Polymerase β
    Meltem Müftüoğlu, Heng Kuan Wong, Syed Z. Imam, David M. Wilson, Vilhelm A. Bohr, Patricia Lynn Opresko · 2006 · Cancer Research
14. The Mutator Form of Polymerase β with Amino Acid Substitution at Tyrosine 265 in the Hinge Region Displays an Increase in both Base Substitution and Frame Shift Errors
    Patricia Lynn Opresko, Joann Balazs Sweasy, Kristin A. Eckert · 1998 · Biochemistry
15. DNA Synthesis and dRPase Activities of Polymerase β Are Both Essential for Single-Nucleotide Patch Base Excision Repair in Mammalian Cell Extracts
    Andrej Ja. Podlutsky, Irina I. Dianova, Samuel H. Wilson, Vilhelm A. Bohr, Grigory L. Dianov · 2000 · Biochemistry
16. Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase ι
    Alexandra Vaisman, Ekaterina G. Frank, Shigenori Iwai, Eiji Ohashi, Haruo Ohmori, Fumio Hanaoka, Roger Woodgate · 2003 · DNA repair
17. Identification and Characterization of Human DNA Polymerase β2, a DNA Polymerase β-Related Enzyme
    Kei-ichi Nagasawa, Kenzo Kitamura, Akihiro Yasui, Yuji Nimura, Kyoji Ikeda, Momoki Hirai, Akio Matsukage, Makoto Nakanishi · 2000 · Journal of Biological Chemistry
18. Genetic linkage between Polι deficiency and increased susceptibility to lung tumors in mice
    Gang‐Hong Lee, Hiroshi Matsushita · 2005 · Cancer Science
19. Human DNA Polymerase ι Promiscuous Mismatch Extension
    Alexandra Vaisman, Agnès Tissier, Ekaterina G. Frank, Myron F. Goodman, Roger Woodgate · 2001 · Journal of Biological Chemistry
20. Consequences of OX40-OX40 ligand interactions in Langerhans cell function: enhanced contact hypersensitivity responses in OX40L-transgenic mice
    Takayuki Sato, Naoto Ishii, Kazuko Murata, Kazu Kikuchi, Satoshi Nakagawa, Lishomwa C. Ndhlovu, Kazuo Sugamura · 2002 · European Journal of Immunology
21. DNA Polymerase e - More Than a Polymerase
    Helmut Pospiech, Juhani Eerik Syväoja · 2003 · The Scientific World JOURNAL
22. Pol ι Is a Candidate for the Mouse Pulmonary Adenoma Resistance 2 Locus, a Major Modifier of Chemically Induced Lung Neoplasia
    Min Wang, Theodora R. Devereux, Haris G. Vikis, Scott D. McCulloch, Wanda M. Holliday, Colleen H. Anna, Yian Wang, Katarzyna Bębenek, Thomas A. Kunkel, Kun‐Liang Guan et al. · 2004 · Cancer Research
23. Trf4 and Trf5 Proteins of Saccharomyces cerevisiae Exhibit Poly(A) RNA Polymerase Activity but No DNA Polymerase Activity
    Lajos Haracska, Robert E. Johnson, Louise Prakash, Satya Prakash · 2005 · Molecular and Cellular Biology
24. A genetic system to identify DNA polymerase β mutator mutants
    Stacy Washington, Margaret S. Yoon, Alexander M. Chagovetz, Shu-Xia Li, Caroline Clairmont, Bradley D. Preston, Kristin A. Eckert, Joann Balazs Sweasy · 1997 · Proceedings of the National Academy of Sciences
25. Phosphorylation of human DNA polymerase by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen
    Isabelle Frouin · 2005 · Nucleic Acids Research
26. Modulation of the 5′-Deoxyribose-5-phosphate Lyase and DNA Synthesis Activities of Mammalian DNA Polymerase β by Apurinic/Apyrimidinic Endonuclease 1
    Donny Wong, Bruce Demple · 2004 · Journal of Biological Chemistry
27. Further Characterization of Human DNA Polymerase δ Interacting Protein 38
    Bin Xie, Hao Li, Qi Wang, Suqing Xie, Amal A. Rahmeh, Wei Hao Dai, Marietta Lee · 2005 · Journal of Biological Chemistry
28. Forward Genetic Screens for Meiotic and Mitotic Recombination-Defective Mutants in Mice
    Laura G. Reinholdt, Terry Ashley, John C. Schimenti, Naoko Shima · 2004 · Humana Press eBooks
29. A tumor necrosis factor α- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase δ and proliferating cell nuclear antigen
    Hua He, Cheng‐Keat Tan, Kathleen M. Downey, Antero G. So · 2001 · Proceedings of the National Academy of Sciences
30. Pre-Steady-State Kinetic Studies of the Fidelity of Human DNA Polymerase μ
    Michelle P. Roettger, Kevin A. Fiala, Susmitha Sompalli, Yuxia Dong, Zucai Suo · 2004 · Biochemistry
31. Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase κ
    Clarisse Bavoux, Jean‐Sébastien Hoffmann, Christophe Cazaux · 2005 · Biochimie
32. Immortalized mouse cell lines that lack a functional Rev3 gene are hypersensitive to UV irradiation and cisplatin treatment
    Linda Zander Balderud, Mats Bemark · 2004 · DNA repair
33. Frequent mutation related with overexpression of DNA polymerase beta in primary tumors and precancerous lesions of human stomach
    Xiaohui Tan, Min Zhao, Kai‐Feng Pan, Ying Dong, Bin Dong, Guijian Feng, Guang Jia, Youyong Lu · 2004 · Cancer Letters
34. The absence of DNA polymerase κ does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene
    Takeyuki Shimizu, Yoichi Shinkai, Tomoo Ogi, Haruo Ohmori, Takachika Azuma · 2003 · Immunology Letters
35. Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene
    D. R. Clark · 2003 · Nucleic Acids Research
36. ヒト胃癌に見られるDNAポリメラーゼβの機能変異 in vitroでの塩基除去修復の不能
    章成 岩永, M Ouchida, K Miyazaki, Katsuji Hori, T Mukai · 1999 · Mutation Research/Genetic Toxicology and Environmental Mutagenesis
37. The Tyr-265-to-Cys mutator mutant of DNA polymerase β induces a mutator phenotype in mouse LN12 cells
    Caroline Clairmont, Latha Narayanan, Ka-Wai Sun, Peter M. Glazer, Joann Balazs Sweasy · 1999 · Proceedings of the National Academy of Sciences
38. The property of DNA polymerase ζ: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control
    Yoshiki Murakumo · 2002 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
39. Elevated expression of DNA polymerase κ in human lung cancer is associated with p53 inactivation: Negative regulation of POLK promoter activity by p53
    Yanqing Wang, Mika Seimiya, Kiyoko Kawamura, Ling Yu, Tomoo Ogi, Keizo Takenaga, Tomotane Shishikura, Akira Nakagawara, Shigeru Sakiyama, Masatoshi Tagawa et al. · 2004 · International Journal of Oncology
40. Assignment of the gene for human DNA polymerase alpha to the X chromosome.
    Teresa S.‐F. Wang, Barbara E. Pearson, HELI A. SUOMALAINEN, Thuluvancheri K. Mohandas, Larry J. Shapiro, Jim Schröder, David Korn · 1985 · Proceedings of the National Academy of Sciences
41. DNA Polymerase β Interacts with TRF2 and Induces Telomere Dysfunction in a Murine Mammary Cell Line
    Poppy P. Fotiadou, Octavian Henegariu, Joann Balazs Sweasy · 2004 · Cancer Research
42. DNA polymerases α, δ, and ɛ localize and function together at replication forks inSaccharomyces cerevisiae
    Shin‐ichiro Hiraga, Aki Hayashi-Hagihara, Tomoko Ohya, Akio Sugino · 2005 · Genes to Cells
43. Stimulation of human DNA polymerase epsilon by MDM2
    Asahara, H. · 2003 · Nucleic Acids Research
44. Normal immunoglobulin gene somatic hypermutation in Polκ–Polι double-deficient mice
    Takeyuki Shimizu, Takachika Azuma, Mariko Ishiguro, Naoko Kanjo, Shuichi Yamada, Haruo Ohmori · 2004 · Immunology Letters
45. Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Polı gene as a candidate for Par2
    Gang‐Hong Lee, Hiroyuki Nishimori, Yasushi Sasaki, Hiroshi Matsushita, Tomoyuki Kitagawa, Takashi Tokino · 2003 · Oncogene
46. The B-Subunit of DNA Polymerase α-Primase Associates with the Origin Recognition Complex for Initiation of DNA Replication
    Masashi Uchiyama, Teresa S.‐F. Wang · 2004 · Molecular and Cellular Biology
47. The role of DNA polymerase beta in determining sensitivity to ionizing radiation in human tumor cells
    Conchita Vens · 2002 · Nucleic Acids Research
48. Hoogsteen base-pairing in DNA replication?
    Jimin Wang · 2005 · Nature
49. Characterization of the mus308 gene in Drosophila melanogaster.
    Edith A. Leonhardt, Daryl S. Henderson, Janet E. Rinehart, James B. Boyd · 1993 · Genetics
50. DNA polymerases η and κ are responsible for error-free translesion DNA synthesis activity over a cis–syn thymine dimer in Xenopus laevis oocyte extracts
    Yoshihiko Yagi, Daichi Ogawara, Shigenori Iwai, Fumio Hanaoka, Masahiro Akiyama, Hisaji Maki · 2005 · DNA repair
51. Analysis of the mammalian recombination protein complex RC-1
    Rolf Jessberger, Gloria Chui, Stuart Linn, Börries Kemper · 1996 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
52. DNA polymerase lambda directly binds to proliferating cell nuclear antigen through its confined C‐terminal region
    Noriko Shimazaki, Takaya Yazaki, Takashi Kubota, Asami Sato, Ayako Nakamura, Shunsuke Kurei, Shingo Toji, Katsuyuki Tamai, Osamu Koiwai · 2005 · Genes to Cells
53. Deregulated DNA polymerase β strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities
    Mathilde Fréchet, Yvan Canitrot, Anne Bieth, Eugenia Dogliotti Y, Christophe Cazaux, Jean‐Sébastien Hoffmann · 2002 · Oncogene
54. The error-prone DNA polymerase zeta catalytic subunit (Rev3) gene is ubiquitously expressed in normal and malignant human tissues.
    K Kawamura, Jiyang O‐Wang, R Bahar, Nobuko Koshikawa, Tomotane Shishikura, Akira Nakagawara, Shigeru Sakiyama, Kagemasa Kajiwara, Masaki Kimura, Masatoshi Tagawa · 2001 · International Journal of Oncology
55. An APE that proofreads
    Josef Jiricny · 2002 · Nature
56. Diagnostics in patients with glutathione synthetase deficiency but without mutations in the exons of the GSS gene
    Runa NJÅLSSON, Katarina Carlsson, Andreas Winkler, Agne Larsson, Svante Norgren · 2003 · Human Mutation
57. Analyses of ultraviolet‐induced focus formation of hREV1 protein
    Yoshiki Murakumo, Sachie Mizutani, Mariko Yamaguchi, Masatoshi Ichihara, Masahide Takahashi · 2006 · Genes to Cells
58. Localization of the Gene for DNA Polymerase ϵ (POLE) to Human Chromosome 12q24.3 and Rat Chromosome 12 by Somatic Cell Hybrid Panels and Fluorescence in Situ Hybridization
    Josiane Szpirer, Florence Pédeutour, Tapio Kesti, Michèle Rivière, Juhani Eerik Syväoja, Claude Turc‐Carel, Claude Szpirer · 1994 · Genomics
59. Possible involvement of the yeast POLIII DNA polymerase in induced gene conversion
    Francis Fabre, Annick Boulet, Gérard Faye · 1991 · Molecular and General Genetics MGG
60. The human DNA polymerase λ interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21 /WAF1/CIP1
    Giovanni Maga, Giuseppina Blanca, Igor Shevelev, Isabelle Frouin, Kristijan Ramadan, Silvio Spadari, Giuseppe Villani, Ulrich Hübscher · 2004 · The FASEB Journal
61. Biological Response to Ionizing Radiation in Mouse Embryo Fibroblasts with a Targeted Disruption of the DNA Polymerase β Gene
    Masahiko Miura, Hiroshi Watanabe, Kiyoshi Okochi, Takehito Sasaki, Hitoshi Shibuya · 2000 · Radiation Research
62. Saving the Ends for Last: The Role of Pol μ in DNA End Joining
    Tanya T. Paull · 2005 · Molecular Cell
63. Polymerase μ is up‐regulated during the T cell‐dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts
    Daniel Lucas, Teresa Laı́n de Lera, Manuel A. González, José F. Ruiz, Orlando Domı́nguez, Jesús C. Casanova, Carlos Martínez‐A, Luis Blanco, António Bernad · 2005 · European Journal of Immunology
64. Direct Interaction of p21 with p50, the Small Subunit of Human DNA Polymerase Delta
    Hao Li, Bin Xie, Amal A. Rahmeh, Yajing Zhou, Marietta Lee · 2006 · Cell Cycle
65. Mapping of the gene for DNA polymerase β to mouse Chromosome 8
    O. Wesley McBride, Christine A. Kozak, Samuel H. Wilson · 2008 · Cytogenetics and Cell Genetics
66. The Second Largest Subunit of Mouse DNA Polymerase , DPE2, Interacts with SAP18 and Recruits the Sin3 Co-Repressor Protein to DNA
    MIKI WADA, Hiroshi Miyazawa, R.-S. Wang, T. Mizun, A. Sato, Makoto Asashima, Fumio Hanaoka · 2002 · The Journal of Biochemistry
67. Assembly of High-Resolution Bacterial Artificial Chromosome, P1-Derived Artificial Chromosome, and Cosmid Contigs
    Linda K. Ashworth, Michelle Alegria-Hartman, Matthew Burgin, LM Devlin, Anthony V. Carrano, Mark A. Batzer · 1995 · Analytical Biochemistry
68. Transcription, β–like DNA polymerases and hypermutation
    Claude–Agnès Reynaud, Stéphane Frey, Saïd Aoufouchi, Ahmad Faili, Barbara Bertocci, Auriel Dahan, Eric Flatter, Frédéric Delbos, Sébastien Storck, Carole Zober et al. · 2001 · Philosophical Transactions of the Royal Society B Biological Sciences
69. A mutation detected in DNA polymerase δ cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme
    Odilia Popanda, Thomas Flohr, Gabriele Fox, Heinz Walter Thielmann · 1999 · Journal of Cancer Research and Clinical Oncology
70. DNA polymerase alpha defect in the N syndrome
    Kimberly M. Floy, Russell O. Hess, Lorraine F. Meisner · 1990 · American Journal of Medical Genetics
71. Multiple PolK (POLK) transcripts in mammalian testis
    Caixia Guo, Tianshu Gao, Nils Confer, Susana Velasco-Miguel, Errol C. Friedberg · 2004 · DNA repair
72. Updating the N syndrome: Occurrence of lymphoid malignancy and possible association with an increased rate of chromosome breakage
    Russell O. Hess, Gholam‐Reza Hafez, Lorraine F. Meisner, John M. Opitz, Jay Bernstein · 1987 · American Journal of Medical Genetics
73. Human DNA polymerase alpha. Compensation for heat-labile mouse DNA polymerase alpha and its gene localization on the X chromosome.
    Fumio Hanaoka, Megumi Tandai, Hiroshi Miyazawa, Yasufumi Murakami, Tetsuya Hori, Masaki Yamada · 1984 · PubMed