DNA polymerases and human diseases

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J. N., Rovio, A. T., Bruder, C. E., Bohlooly-Y, M., Gidlöf, S., Oldfors, A., Wibom, R., et al. (2004) · Nature · doi:10.1038/nature02517 · Cited by 2,734 · see citing works

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

Kujoth, G. C., Hiona, A., Pugh, T. D., Someya, S., Panzer, K., Wohlgemuth, S. E., Hofer, T., Seo, A. Y., Sullivan, R., Jobling, W. A., et al. (2005) · Science · doi:10.1126/science.1112125 · Cited by 2,165 · see citing works

DNA Replication in Eukaryotic Cells

Bell, S. P., & Dutta, A. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.110601.135425 · Cited by 2,065 · see citing works

Estimates of the worldwide incidence of 25 major cancers in 1990

Parkin, D. M., Pisani, P., & Ferlay, J. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990315)80:6 · Cited by 2,013 · see citing works

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Gu, H., Marth, J. D., Orban, P. C., Mossmann, H., & Rajewsky, K. (1994) · Science · doi:10.1126/science.8016642 · Cited by 1,397 · see citing works

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

Masutani, C., Kusumoto, R., Yamada, A., Dohmae, N., Yokoi, M., Yuasa, M., Araki, M., Iwai, S., Takio, K., & Hanaoka, F. (1999) · Nature · doi:10.1038/21447 · Cited by 1,292 · see citing works

EUKARYOTIC TRANSLESION SYNTHESIS DNA POLYMERASES: Specificity of Structure and Function

Prakash, S., Johnson, R. E., & Prakash, L. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.082803.133250 · Cited by 999 · see citing works

The Y-Family of DNA Polymerases

Ohmori, H., Friedberg, E. C., Fuchs, R. P., Goodman, M. F., Hanaoka, F., Hinkle, D. C., Kunkel, T. A., Lawrence, C. W., Livneh, Z., Nohmi, T., et al. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00278-7 · Cited by 882 · see citing works

Mammalian DNA nucleotide excision repair reconstituted with purified protein components

Aboussekhra, A., Biggerstaff, M., Shivji, M. K. K., Vilpo, J. A., Moncollin, V., Podust, V. N., Protić, M., Hübscher, U., Egly, J.-M., & Wood, R. D. (1995) · Cell · doi:10.1016/0092-8674(95)90289-9 · Cited by 837 · see citing works

Requirement of mammalian DNA polymerase-β in base-excision repair

Sobol, R. W., Horton, J. K., Kühn, R., Gu, H., Singhal, R. K., Prasad, R., Rajewsky, K., & Wilson, S. H. (1996) · Nature · doi:10.1038/379183a0 · Cited by 834 · see citing works

THE DNA REPLICATION FORK IN EUKARYOTIC CELLS

Waga, S., & Stillman, B. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.721 · Cited by 814 · see citing works

Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

Klungland, A., & Lindahl, T. (1997) · The EMBO Journal · doi:10.1093/emboj/16.11.3341 · Cited by 789 · see citing works

Reconstitution of DNA base excision‐repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.

Kubota, Y., Nash, R. A., Klungland, A., Schär, P., Barnes, D. E., & Lindahl, T. L. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01056.x · Cited by 776 · see citing works

Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes

Goodman, M. F. (2002) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.71.083101.124707 · Cited by 727 · see citing works

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.

Bienko, M., Green, C. M., Crosetto, N., Rudolf, F., Zapart, G., Coull, B., Kannouche, P., Wider, G., Peter, M., Lehmann, A. R., et al. (2005) · Science · doi:10.1126/science.1120615 · Cited by 712 · see citing works

Excision of Deoxyribose Phosphate Residues by DNA Polymerase β During DNA Repair

Matsumoto, Y., & Kim, K. (1995) · Science · doi:10.1126/science.7624801 · Cited by 683 · see citing works

An attempt to unify the structure of polymerases

Delarue, M. H., Poch, O., Tordo, N., Moras, D., & Argos, P. (1990) · Protein Engineering Design and Selection · doi:10.1093/protein/3.6.461 · Cited by 638 · see citing works

Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions

Johnson, R. E., Washington, M. T., Haracska, L., Prakash, S., & Prakash, L. (2000) · Nature · doi:10.1038/35023030 · Cited by 632 · see citing works

XRCC1 Polypeptide Interacts with DNA Polymerase and Possibly Poly (ADP-Ribose) Polymerase, and DNA Ligase III Is a Novel Molecular 'Nick-Sensor' In Vitro

Caldecott, K. W., Aoufouchi, S., Johnson, P., & Shall, S. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.22.4387 · Cited by 620 · see citing works

Compilation, alignment, and phylogenetic relationships of DNA polymerases

Braithwaite, D. K., & Ito, J. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.4.787 · Cited by 586 · see citing works

Deoxycytidyl transferase activity of yeast REV1 protein

Nelson, J. R., Lawrence, C. W., & Hinkle, D. C. (1996) · Nature · doi:10.1038/382729a0 · Cited by 573 · see citing works

A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control

Vaňáčová, Š., Wolf, J., Martin, G., Blank, D., Dettwiler, S., Friedlein, A., Langen, H., Keith, G., & Keller, W. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030189 · Cited by 567 · see citing works

Oxy radicals, lipid peroxidation and DNA damage

Marnett, L. J. (2002) · Toxicology · doi:10.1016/s0300-483x(02)00448-1 · Cited by 563 · see citing works

CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork

Johnson, A. M., & O’Donnell, M. E. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073859 · Cited by 563 · see citing works

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

Waga, S., & Stillman, B. (1994) · Nature · doi:10.1038/369207a0 · Cited by 557 · see citing works

Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: clinical and molecular genetic study

Luoma, P., Melberg, A., Rinne, J. O., Kaukonen, J. A., Nupponen, N. N., Chalmers, R. M., Oldfors, A., Rautakorpi, I., Peltonen, L., Majamaa, K., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16983-3 · Cited by 548 · see citing works

Rad18 guides polη to replication stalling sites through physical interaction and PCNA monoubiquitination

Watanabe, K., Tateishi, S., Kawasuji, M., Tsurimoto, T., Inoue, H., & Yamaizumi, M. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600383 · Cited by 538 · see citing works

Mechanisms of accurate translesion synthesis by human DNA polymerase η

Masutani, C., Kusumoto, R., Iwai, S., & Hanaoka, F. (2000) · The EMBO Journal · doi:10.1093/emboj/19.12.3100 · Cited by 504 · see citing works

POLG mutations associated with Alpers' syndrome and mitochondrial DNA depletion

Naviaux, R. K., & Nguyen, K. V. (2004) · Annals of Neurology · doi:10.1002/ana.20079 · Cited by 459 · see citing works

Xeroderma pigmentosum variant (XP‐V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

Masutani, C., Araki, M., Yamada, A., Kusumoto, R., Nogimori, T., Maekawa, T., Iwai, S., & Hanaoka, F. (1999) · The EMBO Journal · doi:10.1093/emboj/18.12.3491 · Cited by 434 · see citing works

Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69

Wang, J., Sattar, A. K. M. A., Wang, C. C., Karam, J. D., Konigsberg, W. H., & Steitz, T. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80296-2 · Cited by 430 · see citing works

DNA Polymerase γ, The Mitochondrial Replicase

Kaguni, L. S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161455 · Cited by 414 · see citing works

Reconstitution of complete SV40 DNA replication with purified replication factors.

Waga, S., Bauer, G. A., & Stillman, B. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34146-7 · Cited by 404 · see citing works

DNA polymerase ϵ links the DNA replication machinery to the S phase checkpoint

Navas, T. A., Zhou, Z. Y., & Elledge, S. J. (1995) · Cell · doi:10.1016/0092-8674(95)90448-4 · Cited by 403 · see citing works

Fidelity of Human DNA Polymerase η

Johnson, R. E., Washington, M. T., Prakash, S., & Prakash, L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.11.7447 · Cited by 399 · see citing works

Telomere-binding Protein TRF2 Binds to and Stimulates the Werner and Bloom Syndrome Helicases

Opresko, P. L., von Kobbe, C., Lainé, J., Harrigan, J. A., Hickson, I. D., & Bohr, V. A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205396200 · Cited by 389 · see citing works

Reconstitution of 5′-Directed Human Mismatch Repair in a Purified System

Zhang, Y., Yuan, F., Presnell, S. R., Tian, K., Gao, Y., Tomkinson, A. E., Gu, L., & Li, G. (2005) · Cell · doi:10.1016/j.cell.2005.06.027 · Cited by 380 · see citing works

Trading Places: How Do DNA Polymerases Switch during Translesion DNA Synthesis?

Friedberg, E. C., Lehmann, A. R., & Fuchs, R. P. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.03.032 · Cited by 376 · see citing works

A Biochemically Defined System for Mammalian Nonhomologous DNA End Joining

Ma, Y., Lu, H., Tippin, B. L., Goodman, M. F., Shimazaki, N., Koiwai, O., Hsieh, C., Schwarz, K., & Lieber, M. R. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.11.017 · Cited by 357 · see citing works

Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis

Guo, C., Fischhaber, P. L., Luk‐Paszyc, M. J., Masuda, Y., Zhou, J., Kamiya, K., Kisker, C., & Friedberg, E. C. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg626 · Cited by 353 · see citing works

Interaction of human apurinic endonuclease and DNA polymerase β in the base excision repair pathway

Bennett, R. A. O., Wilson, D. M., Wong, D., & Demple, B. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7166 · Cited by 350 · see citing works

A third essential DNA polymerase in S. cerevisiae

Morrison, A., Araki, H., Clark, A., Hamatake, R. K., & Sugino, A. (1990) · Cell · doi:10.1016/0092-8674(90)90391-q · Cited by 350 · see citing works

Roles of yeast DNA polymerases δ and ζ and of Rev1 in the bypass of abasic sitesPreprint

Haracska, L., Unk, I., Johnson, R. E., Johansson, E., Burgers, P., Prakash, S., & Prakash, L. (2001) · Genes & Development · doi:10.1101/gad.882301 · Cited by 347 · see citing works

Structure of the Catalytic Core of S. cerevisiae DNA Polymerase η

Trincão, J., Johnson, R. E., Escalante, C. R., Prakash, S., Prakash, L., & Aggarwal, A. K. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00306-9 · Cited by 344 · see citing works

DNA Primases

Frick, D. N., & Richardson, C. C. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.39 · Cited by 344 · see citing works

The lyase activity of the DNA repair protein β-polymerase protects from DNA-damage-induced cytotoxicity

Sobol, R. W., Prasad, R., Evenski, A. J., Baker, A. E., Yang, X., Horton, J. K., & Wilson, S. H. (2000) · Nature · doi:10.1038/35015598 · Cited by 343 · see citing works

A role for p53 in base excision repair

Zhou, J., Ahn, J., Wilson, S. H., & Prives, C. (2001) · The EMBO Journal · doi:10.1093/emboj/20.4.914 · Cited by 333 · see citing works

A Gradient of Template Dependence Defines Distinct Biological Roles for Family X Polymerases in Nonhomologous End Joining

McElhinny, S. A. N., Havener, J. M., García–Díaz, M., Juárez, R., Bębenek, K., Kee, B. L., Blanco, L., Kunkel, T. A., & Ramsden, D. A. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.06.012 · Cited by 327 · see citing works

MUTANTS OF YEAST DEFECTIVE IN MUTATION INDUCED BY ULTRAVIOLET LIGHT

Lemontt, J. F. (1971) · Genetics · doi:10.1093/genetics/68.1.21 · Cited by 325 · see citing works

DNA polymerase beta-like nucleotidyltransferase superfamily: identification of three new families, classification and evolutionary history

Aravind, L. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.7.1609 · Cited by 322 · see citing works

Replication by human DNA polymerase-ι occurs by Hoogsteen base-pairing

Nair, D. T., Johnson, R. E., Prakash, S., Prakash, L., & Aggarwal, A. K. (2004) · Nature · doi:10.1038/nature02692 · Cited by 309 · see citing works

Mitochondrial DNA Polymerase W748S Mutation: A Common Cause of Autosomal Recessive Ataxia with Ancient European Origin

Hakonen, A. H., Heiskanen, S., Juvonen, V., Lappalainen, I., Luoma, P. T., Rantamäki, M., Goethem, G. V., Löfgren, A., Hackman, P., Paetau, A. E., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/444548 · Cited by 309 · see citing works

Human DNA Polymerase η Promotes DNA Synthesis from Strand Invasion Intermediates of Homologous Recombination

McIlwraith, M. J., Vaisman, A., Liu, Y., Fanning, E., Woodgate, R., & West, S. C. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.10.001 · Cited by 304 · see citing works

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ

Gibbs, P., McGregor, W. G., Maher, V. M., Nisson, P. E., & Lawrence, C. W. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.12.6876 · Cited by 301 · see citing works

Association of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair

Mahajan, K. N., Nick McElhinny, S. A., Mitchell, B. S., & Ramsden, D. A. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.14.5194-5202.2002 · Cited by 293 · see citing works

Infantile hepatocerebral syndromes associated with mutations in the mitochondrial DNA polymerase- A

Ferrari, G. (2005) · Brain · doi:10.1093/brain/awh410 · Cited by 292 · see citing works

Generation of single-nucleotide repair patches following excision of uracil residues from DNA.

Dianov, G. L., Price, A., & Lindahl, T. L. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.4.1605 · Cited by 287 · see citing works

Nucleotide Excision Repair DNA Synthesis by DNA Polymerase .epsilon. in the Presence of PCNA, RFC, and RPA

Shivji, M. K. K., Podust, V. N., Hübscher, U., & Wood, R. D. (1995) · Biochemistry · doi:10.1021/bi00015a012 · Cited by 279 · see citing works

Domain structure, localization, and function of DNA polymerase η, defective in xeroderma pigmentosum variant cellsPreprint

Kannouche, P., Broughton, B. C., Volker, M., Hanaoka, F., Mullenders, L. H. F., & Lehmann, A. R. (2001) · Genes & Development · doi:10.1101/gad.187501 · Cited by 278 · see citing works

DNA Polymerase ε Catalytic Domains Are Dispensable for DNA Replication, DNA Repair, and Cell Viability

Kesti, T., Flick, K. M., Keränen, S., Syväoja, J. E., & Wittenberg, C. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80361-5 · Cited by 276 · see citing works

Mutations of mitochondrial DNA polymerase γA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia

Lamantea, E., Tiranti, V., Bordoni, A., Toscano, A., Bono, F., Servidei, S., Papadimitriou, A., Spelbrink, H., Silvestri, L., Casari, G., et al. (2002) · Annals of Neurology · doi:10.1002/ana.10278 · Cited by 270 · see citing works

DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA mutator in eukaryotic cells

Domı́nguez, O., Ruiz, J. F., de Lera, T. L., García–Díaz, M., González, M. A., Kirchhoff, T., Martínez‐A, C., Bernad, A., & Blanco, L. (2000) · The EMBO Journal · doi:10.1093/emboj/19.7.1731 · Cited by 268 · see citing works

DNA polymerase lambda (Pol λ), a novel eukaryotic DNA polymerase with a potential role in meiosis 1 1Edited by M. Yaniv

García–Díaz, M., Domı́nguez, O., López-Fernández, L. A., de Lera, L. T., Sanı́ger, M. L., Ruiz, J. F., Párraga, M., Garcı́a-Ortiz, M. J., Kirchhoff, T., del Mazo, J., et al. (2000) · Journal of Molecular Biology · doi:10.1006/jmbi.2000.4005 · Cited by 264 · see citing works

<i>POLG</i> mutations in neurodegenerative disorders with ataxia but no muscle involvement

Van Goethem, G., Luoma, P., Rantamäki, M., Al Memar, A., Kaakkola, S., Hackman, P., Krahe, R., Löfgren, A., Martin, J. J., De Jonghe, P., et al. (2004) · Neurology · doi:10.1212/01.wnl.0000140494.58732.83 · Cited by 261 · see citing works

Functions of DNA polymerases

Bebenek, K., & Kunkel, T. A. (2004) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(04)69005-x · Cited by 258 · see citing works

A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates

Jarosz, D. F., Godoy, V. G., Delaney, J. C., Essigmann, J. M., & Walker, G. C. (2006) · Nature · doi:10.1038/nature04318 · Cited by 258 · see citing works

Interaction of hREV1 with three human Y‐family DNA polymerases

Ohashi, E., Murakumo, Y., Kanjo, N., Akagi, J., Masutani, C., Hanaoka, F., & Ohmori, H. (2004) · Genes to Cells · doi:10.1111/j.1356-9597.2004.00747.x · Cited by 256 · see citing works

Double-Strand Break Repair in Yeast Requires Both Leading and Lagging Strand DNA Polymerases

Holmes, A. M., & Haber, J. E. (1999) · Cell · doi:10.1016/s0092-8674(00)80554-1 · Cited by 256 · see citing works

The overexpression of specialized DNA polymerases in cancer

Albertella, M. R., Lau, A., & O’Connor, M. J. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.01.005 · Cited by 252 · see citing works

Recessive POLG mutations presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia

Goethem, G. V., Martin, J. J., Dermaut, B., Löfgren, A., Wibail, A., Ververken, D., Tack, P., Dehaene, I., Zandijcke, M. V., Moonen, M., et al. (2003) · Neuromuscular Disorders · doi:10.1016/s0960-8966(02)00216-x · Cited by 245 · see citing works

The Role of Base Excision Repair in the Sensitivity and Resistance to Temozolomide-Mediated Cell Death

Trivedi, R. N., Almeida, K. H., Fornsaglio, J. L., Schamus, S., & Sobol, R. W. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0715 · Cited by 242 · see citing works

DNA repair synthesis in human fibroblasts requires DNA polymerase delta.

Nishida, C., Reinhard, P., & Linn, S. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57421-x · Cited by 240 · see citing works

Is There a Link Between DNA Polymerase Beta and Cancer?

Starcevic, D., Dalal, S., & Sweasy, J. B. (2004) · Cell Cycle · doi:10.4161/cc.3.8.1062 · Cited by 240 · see citing works

An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3′ mispaired DNA

Chou, K.-M., & Cheng, Y.-C. (2002) · Nature · doi:10.1038/415655a · Cited by 239 · see citing works

Physical and Functional Interactions of Human DNA Polymerase η with PCNA

Haracska, L., Johnson, R. E., Unk, I., Phillips, B., Hurwitz, J., Prakash, L., & Prakash, S. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.21.7199-7206.2001 · Cited by 235 · see citing works

Identification of an Intrinsic 5′-Deoxyribose-5-phosphate Lyase Activity in Human DNA Polymerase λ

García–Díaz, M., Bębenek, K., Kunkel, T. A., & Blanco, L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106336200 · Cited by 230 · see citing works

Interactions in the Error-prone Postreplication Repair Proteins hREV1, hREV3, and hREV7

Murakumo, Y., Ogura, Y., Ishii, H., Numata, S., Ichihara, M., Croce, C. M., Fishel, R. A., & Takahashi, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102051200 · Cited by 230 · see citing works

Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[ a ]pyrene

Ogi, T., Shinkai, Y., Tanaka, K., & Ohmori, H. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222377899 · Cited by 229 · see citing works

Human Mismatch Repair

Constantin, N., Dzantiev, L., Kadyrov, F. A., & Modrich, P. L. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509701200 · Cited by 225 · see citing works

Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase β

Sugo, N., Aratani, Y., Nagashima, Y., Kubota, Y., & Koyama, H. (2000) · The EMBO Journal · doi:10.1093/emboj/19.6.1397 · Cited by 221 · see citing works

Role of DNA Polymerase β in the Excision Step of Long Patch Mammalian Base Excision Repair

Dianov, G. L., Prasad, R., Wilson, S. H., & Bohr, V. A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.20.13741 · Cited by 217 · see citing works

BRCT Domain-containing Protein TopBP1 Functions in DNA Replication and Damage Response

Mäkiniemi, M., Hillukkala, T., Tuusa, J. T., Reini, K., Vaara, M., Huang, D., Pospiech, H., Majuri, I., Westerling, T., Mäkelä, T. P., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102245200 · Cited by 217 · see citing works

POLQ (Pol ), a DNA polymerase and DNA-dependent ATPase in human cells

Seki, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg814 · Cited by 213 · see citing works

UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, γ-H2AX formation, and Mre11 relocalization

Limoli, C. L., Giedzinski, E., Bonner, W. M., & Cleaver, J. E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.231611798 · Cited by 210 · see citing works

High‐efficiency bypass of DNA damage by human DNA polymerase Q

Seki, M., Masutani, C., Yang, L. W., Schuffert, A., Iwai, S., Bahar, İ., & Wood, R. D. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600424 · Cited by 209 · see citing works

The Saccharomyces cerevisiae DNA Polymerase α Catalytic Subunit Interacts with Cdc68/Spt16 and with Pob3, a Protein Similar to an HMG1-Like Protein

Wittmeyer, J., & Formosa, T. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.7.4178 · Cited by 208 · see citing works

Co-localization in replication foci and interaction of human Y-family members, DNA polymerase polη and REVl protein

Tissier, A., Kannouche, P. L., Reck, M.-P., Lehmann, A. R., Fuchs, R. P., & Cordonnier, A. M. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.06.015 · Cited by 207 · see citing works

Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-δ p66 Subunit and Flap Endonuclease-1

Bruning, J. B., & Shamoo, Y. (2004) · Structure · doi:10.1016/j.str.2004.09.018 · Cited by 206 · see citing works

Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius

Hopfner, K., Eichinger, A., Engh, R. A., Laue, F., Ankenbauer, W., Huber, R., & Angerer, B. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3600 · Cited by 206 · see citing works

Long Patch Base Excision Repair with Purified Human Proteins

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Synthesis of DNA by DNA polymerase epsilon in vitro.

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Addendum

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Genetic Instability of Cancer

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