The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
RNAi Knockdown of a Salivary Transcript Leading to Lethality in the Pea Aphid,Acyrthosiphon pisum
Open accessAbstract
Abstract Injection of siRNA (small interfering RNA) into parthenogenetic adult pea aphids (Acyrthosiphon pisum) is shown here to lead to depletion of a target salivary gland transcript. The siRNA was generated from double stranded RNA that covered most of the open reading frame of the transcript, which we have called Coo2. The Coo2 transcript level decreases dramatically over a 3-day period after injection of siRNA. With a lag of 1 to 2 days, the siCoo2-RNA injected insects died, on average 8 days before the death of control insects injected with siRNA for green fluorescent protein. It appears, therefore, that siRNA injections into adults will be a useful tool in studying the roles of individual transcripts in aphid salivary glands and suggests that siCoo2-RNA injections can be a useful positive control in such studies.
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Cites
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Cited by
Effector proteins that modulate plant–insect interactions
Hogenhout, S. A., & Bos, J. I. (2011) · Current Opinion in Plant Biology · doi:10.1016/j.pbi.2011.05.003 · Cited by 473
Molecular mechanisms influencing efficiency of RNA interference in insects
Cooper, A. M., Silver, K., Zhang, J., Park, Y., & Zhu, K. Y. (2019) · Pest Management Science · doi:10.1002/ps.5126 · Cited by 435
Self-citationSilencing of Aphid Genes by dsRNA Feeding from Plants
Pitino, M., Coleman, A. D., Maffei, M. E., Ridout, C. J., & Hogenhout, S. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025709 · Cited by 414
Mutti, N. S., Louis, J., Pappan, L. K., Pappan, K., Begum, K., Chen, M.-S., Park, Y., Dittmer, N., Marshall, J., Reese, J. C., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708958105 · Cited by 393
Self-citationYan, S., Qian, J., Cai, C., Ma, Z., Li, J., Yin, M., Ren, B., & Shen, J. (2020) · Journal of Pest Science · doi:10.1007/s10340-019-01157-x · Cited by 281
Metadata
- Authors
- Mutti, N. S., Park, Y., Reese, J. C., & Reeck, G. R.
- Venue
- Journal of Insect Science
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-10
- Volume
- 6
- Issue
- 38
- Pages
- 1-7
- ISSN
- 1536-2442 (ISSN-L)
- OpenAlex
- W2108284976
- Cited by
- 343
- References
- 1
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: RNAi Knockdown of a Salivary Transcript Leading to Lethality in the Pea Aphid,Acyrthosiphon pisum. https://app.cochat.ai/papers/10.1673/031.006.3801
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- Mutti, N. S., Park, Y., Reese, J. C., & Reeck, G. R. (2006). RNAi Knockdown of a Salivary Transcript Leading to Lethality in the Pea Aphid,Acyrthosiphon pisum. Journal of Insect Science. https://doi.org/10.1673/031.006.3801
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