Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

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Items 101–186 of 186

1. Metformin Suppresses Pancreatic Tumor Growth With Inhibition of NFκB/STAT3 Inflammatory Signaling
   Xiang‐Lin Tan, Kalyan K. Bhattacharyya, Shamit Kumar Dutta, William R. Bamlet, Kari G. Rabe, Enfeng Wang, Thomas C. Smyrk, Ann L. Oberg, Gloria M. Petersen, Debabrata Mukhopadhyay · 2015 · Pancreas
2. The Clinical Effect of Metformin on the Survival of Lung Cancer Patients with Diabetes: A Comprehensive Systematic Review and Meta-analysis of Retrospective Studies
   Xun Cao, Zhesheng Wen, Xudong Wang, Yong Li, Kui‐Yuan Liu, Xin Wang · 2017 · Journal of Cancer
3. Metformin Treatment Prevents Sedentariness Related Damages in Mice
   Pamela Senesi, Anna Montesano, Livio Luzi, Roberto Codella, Stefano Benedini, Ileana M. Terruzzi · 2015 · Journal of Diabetes Research
4. Treatment with Insulin Analog X10 and IGF-1 Increases Growth of Colon Cancer Allografts
   Henning Hvid, Marie‐José Blouin, Elena Birman, Jesper Damgaard, Fritz Poulsen, Johannes Josef Fels, Christian Fledelius, Bo F. Hansen, Michaël Pollak · 2013 · PLoS ONE
5. Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells
   Juan Du, Hui-rong Shi, Fang Ren, Jing-lu Wang, Qinghua Wu, Xia Li, Ruitao Zhang · 2017 · BMC Cancer
6. Do cancer cells care if their host is hungry?
   Pollak, Michael · 2009 · Cell Metabolism
7. Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma
   Ambrish Kumar, Nadia Al-Sammarraie, Donald J. DiPette, Ugra Sen Singh · 2014 · Oncotarget
8. Metformin and Gynecologic Cancers
   J.E. Stine, Victoria Lin Bae-Jump · 2014 · Obstetrical & Gynecological Survey
9. IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer
   Carly Jade Dool, Haider Mashhedi, Mahvash Zakikhani, Stéphanie David, Yunhua Zhao, Elena Birman, Joan M. Carboni, Marco M. Gottardis, Marie‐José Blouin, Michaël Pollak · 2011 · Endocrine Related Cancer
10. Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
    Mary Jo Cantoria, László G. Boros, Emmanuelle J. Meuillet · 2013 · Metabolomics
11. Is it time to test biguanide metformin in the treatment of melanoma?
    Michaël Cerezo, Tijana Tomić, Robert Ballotti, Stéphane Rocchi · 2014 · Pigment Cell & Melanoma Research
12. Combined Cancer Therapy with Non-Conventional Drugs: All Roads Lead to AMPK
    Suning Chen, Xingmei Zhu, Xiaofeng Lai, Tian Lin Xiao, Aidong Wen, Jian Zhang · 2014 · Mini-Reviews in Medicinal Chemistry
13. Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA
    Delfina Costa, Arianna Gigoni, Roberto Würth, Ranieri Cancedda, Tullio Florio, Aldo Pagano · 2014 · Cancer Cell International
14. Loss of function of PTEN alters the relationship between glucose concentration and cell proliferation, increases glycolysis, and sensitizes cells to 2-deoxyglucose
    Marie‐José Blouin, Yunhua Zhao, Mahvash Zakikhani, Carolyn Algire, Esther Piura, Michaël Pollak · 2009 · Cancer Letters
15. Survival benefit associated with metformin use in inoperable non-small cell lung cancer patients with diabetes: A population-based retrospective cohort study
    Chuang, Min-Chun, Yang, Yao-Hsu, Tsai, Ying-Huang, Hsieh, Meng-Jer, Lin, Yu-Ching, Lin, Chin-Kuo, Chen, Pau-Chung, Yang, Tsung-Ming · 2018 · PLOS ONE
16. Metformin plus first-line chemotherapy versus chemotherapy alone in the treatment of epithelial ovarian cancer: a prospective open-label pilot trial
    Ya Zheng, Jie Zhu, Haiyan Zhang, Yanmei Liu, Hong Sun · 2019 · Cancer Chemotherapy and Pharmacology
17. Antihyperglycaemic therapies and cancer risk
    Stefan Z Lutz, Harald Staiger, Andreas Fritsche, Hans‐Ulrich Häring · 2014 · Diabetes and Vascular Disease Research
18. PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs
    Serena Vella, Pier Giulio Conaldi, Tullio Florio, Aldo Pagano · 2016 · PPAR Research
19. Safety and Otoprotection of Metformin in Radiation‐Induced Sensorineural Hearing Loss in the Guinea Pig
    Mario A. Mujica‐Mota, Pezhman Salehi, Slobodan Dević, Sam J. Daniel · 2014 · Otolaryngology
20. Comparison of antiproliferative effects of metformine and progesterone on estrogen-induced endometrial hyperplasia in rats
    Mustafa Taş, Mehmet Serdar Kütük, İbrahim Serdar Serin, Mahmut Tuncay Özgün, Gökalp Öner, Figen Öztürk · 2013 · Gynecological Endocrinology
21. Metformin Mitigated Obesity-Driven Cancer Aggressiveness in Tumor-Bearing Mice
    Chun‐Jung Chen, Chih-Cheng Wu, Cheng-Yi Chang, Jian‐Ri Li, Yen‐Chuan Ou, Wen‐Ying Chen, Su‐Lan Liao, Jiaan‐Der Wang · 2022 · International Journal of Molecular Sciences
22. Metformin reduces the stimulatory effect of obesity on in vivo Walker-256 tumor development and increases the area of tumor necrosis
    Eveline Aparecida Isquierdo Fonseca de Queiroz, María Aparecida Oliveira, Núbia de Souza Lobato, Eliana Hiromi Akamine, Alison Colquhoun, Maria Helena Catelli de Carvalho, Szulim Ber Zyngier, Zuleica Bruno Fortes · 2011 · Life Sciences
23. The Relationship between Metformin and Cancer in Patients with Type 2 Diabetes
    Hyun Hee Chung, Jun Sung Moon, Ji Sung Yoon, Hyoung Woo Lee, Kyu Chang Won · 2013 · Diabetes & Metabolism Journal
24. Metformin Decreases 2-HG Production through the MYC-PHGDH Pathway in Suppressing Breast Cancer Cell Proliferation
    Sehyun Oh, Youngup Cho, Minsun Chang, Sunghyouk Park, Hyuk Nam Kwon · 2021 · Metabolites
25. Metformin inhibits early stage diethylnitrosamine-induced hepatocarcinogenesis in rats
    Woori Jo, Eunsil Yu, Minsun Chang, HYUN-KYU PARK, Hyun‐Ji Choi, Jae-Eun Ryu, Sungwoong Jang, HYO-JU LEE, JA‐JUNE JANG, Woo‐Chan Son · 2015 · Molecular Medicine Reports
26. Impact of diabetes mellitus on the survival of pancreatic cancer: a meta-analysis
    Jian Wang, Hui Shen, Ming Zhan, Weimin Wang, Yang Dong · 2016 · OncoTargets and Therapy
27. Knockdown of LKB1 Sensitizes Endometrial Cancer Cells via AMPK Activation
    Seung Bae Rho, Hyun Jung Byun, Boh-Ram Kim, Chang Hoon Lee · 2021 · Biomolecules & Therapeutics
28. Metformin upregulates E-cadherin and inhibits B16F10 cell motility, invasion and migration
    Guanzhao Liang, MINGLEI DING, Haitao Lu, NA CAO, Yan-Dong Niu, Yang Gao, Jie Lu · 2015 · Oncology Letters
29. Diabetes and cancer: Debating the link through Ca2+/cAMP signalling
    Leandro Bueno Bergantin · 2019 · Cancer Letters
30. Metformin reduces the Walker-256 tumor development in obese-MSG rats via AMPK and FOXO3a
    Eveline Aparecida Isquierdo Fonseca de Queiroz, Eliana Hiromi Akamine, Maria Helena Catelli de Carvalho, Sandra Coccuzzo Sampaio, Zuleica Bruno Fortes · 2014 · Life Sciences
31. Does Metformin Reduce Cancer Risks? Methodologic Considerations
    Asieh Golozar, Shuiqing Liu, Joseph A. Lin, Kimberly S. Peairs, Hsin‐Chieh Yeh · 2016 · Current Diabetes Reports
32. Metformin and asarone inhibit HepG2 cell proliferation in a high glucose environment by regulating AMPK and Akt signaling pathway
    Bhrigu Kumar Das, Rachel M. Knott, Pramod Channabasappa Gadad · 2021 · Future Journal of Pharmaceutical Sciences
33. The Effect of Metformin on Mortality Among Diabetic Cancer Patients: A Systematic Review and Meta-analysis
    Xun Cao, Yaopan Wu, Jing Wang, Kui‐Yuan Liu, Xin Wang · 2017 · JNCI Cancer Spectrum
34. Manipulation of Metabolic Pathways and Its Consequences for Anti-Tumor Immunity: A Clinical Perspective
    Huang‐Yu Yang, Chao-Yi Wu, Jonathan D. Powell, Kun‐Lin Lu · 2020 · International Journal of Molecular Sciences
35. Is metformin a geroprotector? A peek into the current clinical and experimental data
    Agnieszka Zajda, Kristiina M. Huttunen, Joanna Sikora, Maria Podsiedlik, Magdalena Markowicz-Piasecka · 2020 · Mechanisms of Ageing and Development
36. Betulin inhibits lung carcinoma proliferation through activation of AMPK signaling
    Xian-Dong Li, Yijie Zhang, Jichang Han · 2014 · Tumor Biology · Retracted
37. When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow?
    Noriko N. Yokoyama, Andria P. Denmon, Edward Uchio, Mark L. Jordan, Dan Mercola, Xiaolin Zi · 2015 · Current Pharmacology Reports
38. Prevention of Mutagenesis: New Potential Mechanisms of Metformin Action in Neoplastic Cells
    Frédéric Bost, Issam Ben‐Sahra, Jean‐François Tanti · 2012 · Cancer Prevention Research
39. Inverse relationship between insulin receptor expression and progression in renal cell carcinoma
    Makoto Takahashi, Takamitsu Inoue, Mingguo Huang, Kazuyuki Numakura, Hiroshi Tsuruta, Mitsuru Saito, Atsushi Maeno, Eijiro Nakamura, Shintaro Narita, Norihiko Tsuchiya et al. · 2017 · Oncology Reports
40. Anticancer effects of metformin in experimental animal models of different types of cancer: a systematic review and meta-analysis
    Fan Zhang, Shuai Han, Weijie Song · 2022 · Laboratory Animal Research
41. Increased efficacy of metformin corresponds to differential metabolic effects in the ovarian tumors from obeseversuslean mice
    Jianjun Han, Weiya Zhang Wysham, Yan Zhong, Hui Guo, Lu Zhang, Kim M. Malloy, Hallum K. Dickens, Gene Huh, Douglas Lee, Liza Makowski et al. · 2017 · Oncotarget
42. Current status and frontier tracking of clinical trials on Metformin for cancer treatment
    Zhipeng Wu, Wei Wang, Lengyun Wei, Shenglong Zhu · 2023 · Journal of Cancer Research and Clinical Oncology
43. Metformin and Pancreatic Cancer Metabolism
    Mary Jo Cantoria, Hitendra Patel, László G. Boros, Emmanuelle J. Meuillet · 2014 · InTech eBooks
44. Association of the metformin with the risk of lung cancer: a meta-analysis.
    Li Wang, Yong Song, Guannan Wu, Dongmei Yuan · 2013 · Europe PMC (PubMed Central)
45. Pilot study of oral metformin in cancer‐bearing cats
    Jackie M. Wypij · 2015 · Veterinary and Comparative Oncology
46. Benefits of Metformin Combined with Pemetrexed-Based Platinum Doublets as a First-Line Therapy for Advanced Lung Adenocarcinoma Patients with Diabetes
    Jiun-Long Wang, Yi-Ting Tsai, Ching‐Heng Lin, Abdulkadir Cidem, Theresa Staniczek, Gary Ro‐Lin Chang, Chih‐Ching Yen, Wei Chen, Kowit‐Yu Chong, Chuan‐Mu Chen · 2021 · Biomolecules
47. Metformin for lung cancer prevention and improved survival: a novel approach
    Juliana F. Roos, Mariam Qudsi, Arwa Samara, Madina M. Rahim, Samar A. Al-Bayedh, Hafez Ahmed · 2018 · European Journal of Cancer Prevention
48. Metformin: A stroke of luck
    Mohamad Aljofan, Abduzhappar Gaipov · 2019 · Electronic Journal of General Medicine
49. Cancer Cell Metabolism
    Akash Patnaik, Jason W. Locasale, Lewis C. Cantley · 2011 · Springer eBooks
50. Obesity, Diabetes and Cancer: A Mechanistic Perspective
    Vincenza Cifarelli, SD Hursting · 2015 · International Journal of Diabetology & Vascular Disease Research
51. A-activated protein kinase is required for cell survival and growth in hela-s3 cellsin vivo
    Xuhong Song, Dongyang Huang, Yanmin Liu, Xiaokang Pan, Jing Zhang, Bin Liang · 2014 · IUBMB Life
52. Metformin Inhibits N-Methyl-N-Nitrosourea Induced Gastric Tumorigenesis in db/db Mice
    Shan Zhuang, Yongmei Jian, Yongning Sun · 2017 · Experimental and Clinical Endocrinology & Diabetes
53. Biomarkers of Insulin and the Insulin-Like Growth Factor Axis in Relation to Breast Cancer Risk in Chinese Women
    Yifei Zhu, Tiange Wang, Jiayi Wu, Ou Huang, Li Zhu, Jianrong He, Yafen Li, Weiguo Chen, Xiaosong Chen, Kunwei Shen · 2020 · OncoTargets and Therapy
54. Macronutrient Intake and Cancer: How Does Dietary Restriction Influence Tumor Growth and Why Should We Care?
    Michaël Pollak · 2009 · Cancer Prevention Research
55. Identification of patient characteristics associated with survival benefit from metformin treatment in patients with stage I non–small cell lung cancer
    Peter L. Elkin, Sarah Mullin, Sheldon J. Tetewsky, Skyler D. Resendez, Wilmon McCray, Joseph J. Barbi, Sai Yendamuri · 2022 · Journal of Thoracic and Cardiovascular Surgery
56. Metformine et cancer. Du diabète au cancer : de nouvelles perspectives thérapeutiques pour la metformine
    Benoı̂t Viollet, Marc Foretz · 2011 · Médecine des Maladies Métaboliques
57. Insulin and Insulin-Like Growth Factor-1 Associated Cancers
    Sanjay Kumar Dey, Sabyasachi Senapati · 2021 · Springer eBooks
58. Diabetes Mellitus and Allopathic Medication Increase the Risk of Cancer Malignancy, but no Side Effect Associated with the Use of Antidiabetic Herbal Medicine
    Sanjeev Kumar · 2020 · Current Research in Diabetes & Obesity Journal
59. Structural basis of polypharmacological effects of metformin
    Weiwei Han, Lei Xie · 2012 · IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)
60. Repurposing Metformin for Lung Cancer Management
    Chuan‐Mu Chen, Jiun-Long Wang, Yi-Ting Tsai, Jie-Hau Jiang, Hsiao‐Ling Chen · 2017 · InTech eBooks
61. Is it the time for metformin to take place in adjuvant treatment of Her-2 positive breast cancer? Teaching new tricks to old dogs
    Banu Şarer Yürekli, Burçak Karaca, Şevki Çetinkalp, Rüçhan Uslu · 2009 · Medical Hypotheses
62. Antidiabetic drugs and the risk of cancer: beneficial, neutral, or detrimental?
    Taoreed Adegoke Azeez, Sharif Adeniyi Folorunso, Chinedu Eguzozie, Adeleke Adedapo Adegboyega · 2021 · Forum of Clinical Oncology
63. THE EFFECTS OF METFORMIN ON PANCREATIC CANCER METABOLISM
    Mary Jo Cantoria · 2014 · UA Campus Repository (The University of Arizona)
64. Mouse Models to Study Metformin Effects in Carcinogenesis
    Abraham Schneider · 2015 · Energy balance and cancer
65. Metformin and lung cancer
    Sai Yendamuri · 2014 · The Journal of Clinical and Scientific Research
66. Multimodality imaging assessments of response to metformin therapy for breast cancer in nude mice
    Yi Mao, Rui Xia, Lei Wang, Yuqing Wang, Fabao Gao · 2013 · Chinese Medical Journal
67. Efeito da metformina sobre o desenvolvimento tumoral na obesidade: mecanismos envolvidos.
    Eveline Aparecida Isquierdo Fonseca de Queiroz · 2013
68. Influência da obesidade e da resistência à insulina sobre o desenvolvimento tumoral: efeito da metformina
    Eveline Aparecida Isquierdo Fonseca de Queiroz · 2010
69. Targeting AKT/mTOR Signaling Pathways During Murine Skin Tumor Promotion and the Impact of Dietary Energy Balance Manipulation
    Laura A Checkley · 2012 · Digital Commons-TMC (Texas Medical Center)
70. Determining the Role of Autophagy in HER2/neu-Induced Mammary Tumor Dormancy and Recurrence
    Samantha Dwyer · 2013 · Scholarly Commons (University of Pennsylvania)
71. Strategies for Targeting Cancer Stem Cells
    R. Allan Mufson · 2015 · Wiley-VCH eBooks
72. Review Article: Metformin and lung cancer
    Sai Yendamuri · 2014
73. Implicating insulin in neoplastic growth and metabolism
    Haider Mashhedi · 2011
74. Metformin as Adjuvant Therapy in Ovarian and Endometrial Cancers
    Leslie Horn Clark, Victoria Lin Bae-Jump · 2017 · Energy balance and cancer
75. Metformine — a new drug for the prevention and treatment of human malignant tumors
    Н. И. Лисяный · 2012 · Ukrainian Neurosurgical Journal
76. Hypoglycemic therapy and the risks of developing oncopathology among patients with type 2 diabetes (literature review).
    Bazarbekova Rimma Bazarbekovna, I.S. Bektayeva, A.B. Konyrbayeva, M.M. Omarova, D.K. Abseitova, Assem Kazbekova, I.A. Suslova, A.T. Moldasheva, N.E. Balazhanova, S.M. Abdazimova · 2018 · Journal Medicine
77. FOXO3a em leiomioma e leiomiossarcoma uterinos: avaliação de seu potencial para terapia alvo in vitro
    Anamaria Ritti Ricci · 2019
78. Innovations in the treatment of non-small cell lung cancer
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79. Faculty Opinions recommendation of Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis.
    Asad Umar · 2012 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
80. Efeitos do 17-estradiol e da metformina na captação de glicose, ativação das vias de sinalização de FOXO3a e do receptor de insulina em células ovarianas in vitro
    Isabela de Souza Faria · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
81. Análisis molecular del tipo de muerte celular inducido por la terapia coadyudante: metformina y el oxamato de sodio como inhibidores de la vía mTOR y la glucólisis en un modelo celular triple negativo de cáncer de mama
    Verónica García-Castillo · 2018
82. Data from Finasteride Modifies the Relation between Serum C-Peptide and Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial
    Marian L. Neuhouser, Cathee Till, Alan R. Kristal, Phyllis J. Goodman, Ashraful M. Hoque, Elizabeth A. Platz, Ann W. Hsing, Demetrius Albanes, Howard L. Parnes, Michaël Pollak · 2023
83. Type 2 Diabetes Mellitus and the Risk of Prostate Cancer: A Mendelian Randomization Study
    Shuangcheng Ning, Zhi Zou, Bang Liu, Xiangyu Chen, Jin Wang · 2024 · Research Square
84. Repurposing Metformin: A New Frontier in Cancer Therapy
    Shrenika Patil, Samiksha Sawant, Ms Chandani Kamble · 2025 · International Journal of Advanced Research in Science Communication and Technology
85. Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen
    Ghasak Kais Abd-Alhussain‎ · 2026 · Al-Rafidain Journal of Medical Sciences
86. Diabetes and colorectal cancer : epidemiological and physiopathological studies
    Fatima Mohsen Mroueh · 2017 · theses.fr (ABES)