Sex steroid-producing enzymes in human breast cancer

Suzuki, Takashi, Miki, Yasuhiro, Nakamura, Yasuhiro, Moriya, Takuya, Ito, Kiyoshi, Ohuchi, Noriaki, Sasano, Hironobu·2005·Endocrine Related Cancer

Cited by (183)

Items 101–183 of 183

  1. Improved detectability of sex steroids from frozen sections of breast cancer tissue using GC-triple quadrupole-MS
    Ju-Yeon Moon, Keely May McNamara, Jung‐Jin Lee, Bong Chul Chung, Hironobu Sasano, Man Ho Choi · 2017 · The Journal of Steroid Biochemistry and Molecular Biology
  2. Intratumoral concentration of estrogens and clinicopathological changes in ductal carcinoma in situ following aromatase inhibitor letrozole treatment
    Kiyoshi Takagi, T Ishida, Yasuhiro Miki, Hisashi Hirakawa, Yoichiro Kakugawa, 吾郎 天野, Akiko Ebata, Naoko Mori, Yasuhiro Nakamura, Mika Watanabe et al. · 2013 · British Journal of Cancer
  3. A Targeted-Covalent Inhibitor of 17β-HSD1 Blocks Two Estrogen-Biosynthesis Pathways: In Vitro (Metabolism) and In Vivo (Xenograft) Studies in T-47D Breast Cancer Models
    Donald Poirier, Jenny Roy, René Maltais · 2021 · Cancers
  4. Bacterial Lipopolysaccharides Induce Steroid Sulfatase Expression and Cell Migration through IL-6 Pathway in Human Prostate Cancer Cells
    Hee-Jung Im, Na-Hee Park, Yeo‐Jung Kwon, Sangyun Shin, Donghak Kim, Young‐Jin Chun · 2012 · Biomolecules & Therapeutics
  5. Formulation and biopharmaceutical evaluation of a transdermal patch containing letrozole
    Li Li, Liang Fang, Xinlan Xu, Yu Liu, Yinghua H. Sun, Zhonggui He · 2010 · Biopharmaceutics & Drug Disposition
  6. Substrate inhibition of 17β-HSD1 in living cells and regulation of 17β-HSD7 by 17β-HSD1 knockdown
    Hui Han, Jean-François Thériault, Guang Chen, Sheng‐Xiang Lin · 2017 · The Journal of Steroid Biochemistry and Molecular Biology
  7. Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: Of relevance to clinical understanding?
    Per Eystein Lønning, Jürgen Geisler · 2009 · The Journal of Steroid Biochemistry and Molecular Biology
  8. The interaction between aromatase, metalloproteinase 2,9 and cd44 in breast cancer
    Fábio Bagnoli, Vilmar Marques de Oliveira, Maria Antonieta Longo Galvão da Silva, Giuliana Cássia Morrone Taromaru, José Francisco Rinaldi, Tsutomu Aoki · 2010 · Revista da Associação Médica Brasileira
  9. Androgen and androgen-metabolizing enzymes in metastasized lymph nodes of breast cancer
    Yukiko Shibahara, Yasuhiro Miki, Chikako Sakurada, Keiko Uchida, Shuko Hata, Keely May McNamara, Tomomi Yoda, Kiyoshi Takagi, Yasuhiro Nakamura, Takashi Suzuki et al. · 2013 · Human Pathology
  10. Breast cancer, stem cells and sex hormones. Part 3: The impact of the menopause and hormone replacement
    John Eden · 2010 · Maturitas
  11. Intratumoral Estrogen Concentration and Expression of Estrogen-Induced Genes in Male Breast Carcinoma: Comparison with Female Breast Carcinoma
    Kiyoshi Takagi, Takuya Moriya, Masafumi Kurosumi, Kimako Oka, Yasuhiro Miki, Akiko Ebata, Takashi Toshima, Shoji Tsunekawa, Hiroyuki Takei, Hisashi Hirakawa et al. · 2012 · Hormones and Cancer
  12. STUDY ON CAUSE–EFFECT RELATIONS AND OPTIMIZATION OF EXEMESTANE-LOADED NANOSTRUCTURED LIPID CARRIERS
    Le Quoc Thang, Nguyen Duc Hanh, Do Quang Duong · 2017 · International Journal of Pharmacy and Pharmaceutical Sciences
  13. Steroid sulfatase and sulfuryl transferase activities in human brain tumors
    Lubomír Kříž, Marie Bičı́ková, M Mohapl, Martin Hill, Ivan Černý, Richard Hampl · 2008 · The Journal of Steroid Biochemistry and Molecular Biology
  14. The interplay of endocrine therapy, steroid pathways and therapeutic resistance: Importance of androgen in breast carcinoma
    Kiyoshi Takagi, Yasuhiro Miki, Takanori Ishida, Hironobu Sasano, Takashi Suzuki · 2017 · Molecular and Cellular Endocrinology
  15. The Effect of Grapefruit Intake on Endogenous Serum Estrogen Levels in Postmenopausal Women
    Kristine R. Monroe, Frank Z. Stanczyk, Kathleen Besinque, Malcolm C. Pike · 2013 · Nutrition and Cancer
  16. PERAN ESTROGEN DAN PROGESTERON TERHADAP KANKER PAYUDARA
    Erna Suparman, Eddy Suparman · 2014 · Jurnal Biomedik JBM
  17. The Role of Cancer-Associated Adipocytes (CAA) in the Dynamic Interaction Between the Tumor and the Host
    Marie‐Christine Rio · 2011 · Springer eBooks
  18. Estrogen Stimulation Differentially Impacts Human Male and Female Antigen-Specific T Cell Anti-Tumor Function and Polyfunctionality
    Flor C. Navarro, Stephanie K. Watkins · 2017 · Gender and the Genome
  19. Intratumoral androgen metabolism and actions in invasive lobular carcinoma of the breast
    Tomomi Yoda, Keely May McNamara, Yasuhiro Miki, Mayu Takagi, Yoshiaki Rai, Yasuyo Ohi, Yasuaki Sagara, Kentaro Tamaki, Hisashi Hirakawa, Takanori Ishida et al. · 2014 · Cancer Science
  20. In vitro interactions between mammary fibroblasts (Hs 578Bst) and cancer epithelial cells (MCF-7) modulate aromatase, steroid sulfatase and 17β-hydroxysteroid dehydrogenases
    Xiaoqiang Wang, Xiaoye Sang, Caroline Diorio, Sheng‐Xiang Lin, Charles J. Doillon · 2015 · Molecular and Cellular Endocrinology
  21. Differential effect of hormone therapy on E1S-sulfatase activity in non-malignant and cancerous breast cells in vitro
    Petra Stute, Martin Götte, Ludwig Kiesel · 2007 · Breast Cancer Research and Treatment
  22. Enhanced formation of non-phenolic androgen metabolites with intrinsic oestrogen-like gene transactivation potency in human breast cancer cells: a distinctive metabolic pattern
    Gregorio Pérez‐Palacios, René Santillán, Rocio Garcı́a-Becerra, Elizabeth Borja-Cacho, Fernando Larrea, Pablo Damián‐Matsumura, Leticia González-Núñez, Ana Elena Lemus · 2006 · Journal of Endocrinology
  23. Dynamic Regulation of Steroid Hormone Receptor Transcriptional Activity by Reversible SUMOylation
    Todd Philip Knutson, Carol Ann Lange · 2013 · Vitamins and hormones
  24. Melatonin affects the dynamic steady-state equilibrium of estrogen sulfates in human umbilical vein endothelial cells by regulating the balance between estrogen sulfatase and sulfotransferase
    Alicia González, Carlos Martínez‐Campa, Carolina Alonso‐González, Samuel Cos · 2015 · International Journal of Molecular Medicine
  25. Intratumoral estrogen production and actions in luminal A type invasive lobular and ductal carcinomas
    Mayu Takagi, Yasuhiro Miki, Minoru Miyashita, Shuko Hata, Tomomi Yoda, Hisashi Hirakawa, Yasuaki Sagara, Yoshiaki Rai, Yasuyo Ohi, Kentaro Tamaki et al. · 2016 · Breast Cancer Research and Treatment
  26. A Potent Inhibitor of Steroid Sulfatase (EM-1913) Blocks Tumor Growth in Nude Mice (MCF-7 Xenograft)
    Donald Poirier, Jenny Roy, René Maltais, Diana Paula Ayan · 2015 · Current Enzyme Inhibition
  27. The Measurement of Estrogens
    Geoff Holder, Hugh L.J. Makin, H. Leon Bradlow · 2010 · Springer eBooks
  28. Diverse role of androgen action in human breast cancer
    Kiyoshi Takagi, M. Yamaguchi, Minoru Miyashita, Hironobu Sasano, Takashi Suzuki · 2022 · Endocrine Oncology
  29. Bisphenol A-sulfate conjugate disrupts AURKA transcription and cell cycle in BeWo cytotrophoblasts
    Jumpei Fujiki, Megumi Uchida, Sakurako Tsunoda, Naoyuki Maeda, Hiroki Inoue, Hiroshi Yokota, Hidetomo Iwano · 2022 · Molecular and Cellular Endocrinology
  30. Anti-hormone Therapy: Principles of Endocrine Therapy of Cancer
    Jens Hoffmann, Anette Sommer · 2006 · Topics in medicinal chemistry
  31. Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases
    Daphne Gschwantler‐Kaulich, A. Fink-Retter, Klaus F Czerwenka, Gernot Hudelist, Axel Kaulich, Ernst Kubista, Christian Fridolin Singer · 2010 · Tumor Biology
  32. Effect of testosterone on E1S-sulfatase activity in non-malignant and cancerous breast cells in vitro
    Martin Götte, Kathrin Kalkhake, Sebastian Ploeger, Ludwig Kiesel, Petra Stute · 2009 · The Journal of Steroid Biochemistry and Molecular Biology
  33. Menopausal status, adipose tissue, and breast cancer risk: impact of estrogen replacement therapy
    John Eden · 2013 · Hormone Molecular Biology and Clinical Investigation
  34. Homology modeling meets site-directed mutagenesis: An ideal combination to elucidate the topology of 17β-HSD2
    Christoph P. Sager, Susanne Weber, Matthias Negri, Pauline Banachowicz, Gabriele Möller, Jerzy Adamski, Rolf W. Hartmann, Sandrine Marchais‐Oberwinkler · 2020 · The Journal of Steroid Biochemistry and Molecular Biology
  35. Intracrine Formation of Steroid Hormones in Breast Cancer, Epidermal Keratinocyte, Dermal Fibroblast, and Adipocyte Cell Lines Measured by LC-MS/MS
    Emre Karakus, Andreas Schmid, Andréas Schäffler, Stefan Alexander Wudy, Joachim Geyer · 2025 · International Journal of Molecular Sciences
  36. Melatonin and Breast Cancer: Selective Estrogen Enzyme Modulator Actions
    2013 · BENTHAM SCIENCE PUBLISHERS eBooks
  37. Dual aromatase-steroid sulfatase inhibitors (DASI's) for the treatment of breast cancer: a structure guided ligand based designing approach
    Yogesh Singh, Shalini Jaswal, Satwinder Singh, Sant Kumar Verma, Suresh Thareja · 2022 · Journal of Biomolecular Structure and Dynamics
  38. Treatment of ER-positive breast cancer with FDA-approved aromatase inhibitors
    Nayoung Kim, Kiven Erique Lukong · 2026 · Cancer Treatment and Research Communications
  39. Melatonin and Aromatase in Breast Cancer
    Samuel Cos, Carlos Martínez‐Campa, Alicia González, Virginia Alvarez Garcia, Carolina Alonso‐González, M. Mediavilla, Emilio J. Sánchez‐Barceló · 2013 · Clinical Cancer Drugs
  40. Downregulation of Dihydrotestosterone and Estradiol Levels by HEXIM1
    Fitya Syarifa Mozar, Vikas Sharma, Shashank Gorityala, Jeffrey M. Albert, Yan Xu, Monica M. Montano · 2021 · Endocrinology
  41. Post-menopausal ovarian fibroma associated with steroid hormone synthesis: A case report
    Naomi Sato, Yuko Itakura, Yūji Yoshida, Jun‐ichi Akahira, Fumiyoshi Fujishima, Yasuhiro Nakamura · 2023 · Taiwanese Journal of Obstetrics and Gynecology
  42. Why does oestrogen-only hormone therapy have such a small impact on breast cancer risk? A hypothesis
    John Eden · 2010 · Gynecological Endocrinology
  43. Regulation of Stromal Cells by Sex Steroid Hormones in the Breast Cancer Microenvironment
    M. Yamaguchi, Kiyoshi Takagi, Ai Sato, Yuto Yamazaki, Minoru Miyashita, Atsushi Masamune, Takashi Suzuki · 2024 · Cancers
  44. Expression of 5α-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study
    Gang Zhao, Lu Liu, Van Luu-The, Zhimin Fan, Fernand Labrie, Georges Pelletier · 2010 · Hormone Molecular Biology and Clinical Investigation
  45. Perbedaan Jumlah Leukosit pada Pasien Kanker Payudara Pasca Bedah Sebelum dan Sesudah Radioterapi
    Rizqy Auliya Lubis, Efrida Efrida, Dwitya Elvira · 2017 · Jurnal Kesehatan Andalas
  46. Effects of hormone therapy on estrogen synthesis from E1S in the mammary gland of postmenopausal women
    Petra Stute, Thomas Szuwart, Martina Schlueter, Martin Götte, Jens Packeisen, Ludwig Kiesel · 2008 · Maturitas
  47. Structure, Regulation and Polymorphisms of the Aromatase Gene
    Nobuhiro Harada · 2015 · Resistance to targeted anti-cancer therapeutics
  48. Catalytic characteristics of AKR1C1-AKR1C4 and AKR1C9 on oxymesterone
    Huiling Hu, Shan Li, Chun Zhang, Linfeng Li, Jiaxin Yang, Qi Wu, Lilan Ou, Jiarong You, Ai Sun, Frank Heinrich Wieland et al. · 2024 · Molecular Catalysis
  49. Cell Progression and Survival Functions of Enzymes Secreted in Extracellular Vesicles Associated with Breast and Prostate Cancers
    Cosmos Ifeanyi Onyiba, Niwasini Krishna Kumar, Christopher James Scarlett, Judith Weidenhofer · 2025 · Cells
  50. Postmenopausal Hormone Replacement Therapy and Breast Cancer – Clinicopathologic Associations and Molecular Mechanisms
    Géza Ács, Michael J. Wagoner · 2010 · Springer eBooks
  51. The expression of sex steroid receptors and sex steroid–synthesizing/metabolizing enzymes in metastasized lymph nodes of prostate cancer
    Yasuhiro Nakamura, Kazue Ise, Keely May McNamara, Abdullah Azmahani, Shun Sato, Fumiyoshi Fujishima, Kensuke Joh, Hiroyoshi Suzuki, Koji Mitsuzuka, Yoichi Arai et al. · 2018 · Human Pathology
  52. 5 α -reductase type 3 is a predictive marker for chemotherapy efficacy in breast cancer in an androgen-independent manner
    Kanoko Nakamura, Kiyoshi Takagi, M. Yamaguchi, Ai Sato, Naoki Inoue, Akiko Ebata, Yasuhiro Miki, Minoru Miyashita, Takashi Suzuki · 2025 · The Journal of Steroid Biochemistry and Molecular Biology
  53. Fulvestrant: a guide to its use in hormone receptor-positive metastatic breast cancer in postmenopausal women in the EU
    Lesley J. Scott, Jamie D. Croxtall, Kate McKeage · 2013 · Drugs & Therapy Perspectives
  54. Comprehensive multi-level expression profiling of key biomarkers in breast cancer patients.
    Tayyaba Zia, Bangfan Liu, Amun Nadeem, Abid Hussain, Mostafa A. Abdel-Maksoud, Adel M. Zakri, Muhammad Kazim Bashir, Mubarak Ali, Norina Jabeen, Muhammad Jamil et al. · 2023 · PubMed Central
  55. Evaluation of Hormone receptor status in patients with operable breast cancer: a retrospective study at a Regional Cancer Centre in Northeast India
    Neeta Sinam · 2019 · Journal of Medical Science And clinical Research
  56. Tumor microenvironmental growth factors induce long-term estrogen deprivation resistance in breast cancer
    Kouki Tsuboi, Chiyuki Uematsu, Yuri Yamaguchi, Toshifumi Niwa, Shin‐ichi Hayashi · 2019 · Breast Cancer
  57. Endocrine therapy after aromatase inhibitor therapy in breast cancer
    Mohit Kumar Verma, Yasuhiro Miki, Hironobu Sasano · 2011 · Expert Review of Endocrinology & Metabolism
  58. Fulvestrant in postmenopausal women with locally advanced or metastatic breast cancer that has progressed on prior endocrine therapy: a guide
    Katherine Ann Lyseng-Williamson · 2015 · Drugs & Therapy Perspectives
  59. Alternative Androgen Metabolism in Resistance to Aromatase Inhibitors.
    Matthew J. Sikora · 2011 · Deep Blue (University of Michigan)
  60. Charakterisierung der DNA-Methylierung von Biomarkern in Brust- und Darmkrebs
    Manuel Krispin · 2009 · Publications of the UdS (Saarland University)
  61. L'hormonothérapie dans le cancer du sein et l'observance des traitements : quel est le rôle du pharmacien officinal ?
    Claire Frodeau · 2012 · OpenGrey (Institut de l'Information Scientifique et Technique)
  62. Customization of tamoxifen therapy : not only a dream
    Betzabe Chavez Sanchez · 2011 · Open Archive (Karolinska Institutet)
  63. Who benefits from hormone therapy?
    Masakazu Toi, Yuichi lino · 2006 · Breast Cancer
  64. Design, Synthese und biologische Evaluierung von nichtsteroidalen, potenten und selektiven Inhibitoren der 17beta-Hydroxysteroid Dehydrogenase Typ 1 (17beta-HSD1)
    Erika Ziegler · 2007 · Publications of the UdS (Saarland University)
  65. Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer
    Emilio J. Sánchez‐Barceló, Maria Dolores Mediavilla, Samuel Cos · 2013 · Springer eBooks
  66. Local Control of Steroid Hormone Biosynthesis
    Johannes Hofland · 2012 · EUR Research Repository (Erasmus University Rotterdam)
  67. Structure and biological function of human 3-alpha hydroxysteroid dehydrogenase type 3 in breast cancer
    Bo Zhang · 2014 · Corpus Université Laval (Université Laval)
  68. Charakterisierung der DNA-Methylierung von Biomarkern in Brust- und Darmkrebs
    Naturwissenschaftlich-Technischen Fakultät · 2009
  69. erapie dans le cancer du sein et l'observance des traitements : quel est le r^ ole du pharmacien ocinal ?
    Claire Frodeau · 2013
  70. Intrakrynologia estrogenów a terapia i chemioprewencja w nowotworach piersi* Estrogen intracrinology: therapy and chemoprevention of breast cancer
    Barbara E. Licznerska, Wanda Baer‐Dubowska · 2010
  71. Basic science: (December 2005)
    Robert L. Sutherland, J. Scorer · 2006 · Breast Cancer Online
  72. Immunohistochemical Study on Hormone Receptors and HER2 Status in Invasive Breast Carcinoma and its Therapeutic Implications
    Md Iqbal Karim, Md Tarikul Islam, Nazlima Nargis · 2019 · Bangladesh Critical Care Journal
  73. Mammakarzinom und endogene Hormonexposition
    Inselspital Bern, C. Banz-Janssen · 2013
  74. Biotransformações da bacarina da própolis verde utilizando fungos filamentosos e bactérias da microbiota intestinal
    Adriany Dias Fonseca · 2020 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  75. A Promising Challenge in the Link between Melatonin and Breast Cancer: Exploring the Microbiome-Gut-Brain Axis
    Alicia González-González, Aurora Laborda-Illanes, Soukaina Boutriq, Lidia Sánchez‐Alcoholado, Daniel Castellano‐Castillo, Isaac J. Plaza-Andrades, Jesús Peralta-Linero, María Isabel Queipo‐Ortuño · 2022 · IntechOpen eBooks
  76. Regulación de la expresión de la angiogenina en el cáncer mamario
    Erika Karina Ruvalcaba Paredes · 2008
  77. Expresión de los ARNm que codifican para las enzimas que biotransforman a la testosterona en células humanas de carcinoma mamario
    Leticia González Núñez · 2007
  78. Effect of Dietary Energy Restriction on the Expression of Genes Encoding the Enzymes Involved in Steroidogenesis in Normal Breast Epithelium and Abdominal Adipose Tissue of Women with Excessive Adiposity
    Danila Coradini · 2022 · Archives of Breast Cancer
  79. Mammakarzinom und endogene Hormonexposition
    Stute, Petra, Mueck, A.O. · 2013 · reroDoc Digital Library
  80. Post-translational regulation of steroidogenesis and its clinical relevance in hormone responsive cancers
    Roopika Sankar, Ganesh Venkatraman · 2026 · Seminars in Oncology
  81. Progress in 17β-HSD5 Inhibitor Discovery: Mechanistic Basis, SAR Trends, and Therapeutic Potential
    Suyash Torawane, Pooja Ratre, Yogesh Singh, Shilpa Mandpe, Swanand Kulkarni · 2026 · Journal of Molecular Structure
  82. Mammakarzinom und endogene Hormonexposition
    Deutsche Menopause Gesellschaft e.V., Petra Stute, A. O. Mueck · 2013 · Gynäkologische Endokrinologie
  83. BindingDB Entry 50032861: New drug-like hydroxyphenylnaphthol steroidomimetics as potent and selective 17ß-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of estrogen-dependent diseases.
    BindingDB · 2011 · UC San Diego