Cited by 218Chronic Kidney Disease and DiabetesDialysis and Renal Disease ManagementAcute Kidney Injury Research

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. Prediction, progression and outcomes of chronic kidney disease in older adults.

Anderson, Sharon, Halter, Jeffrey B., Hazzard, William R., Himmelfarb, Jonathan, Horne, Frances McFarland, Kaysen, George A., Kusek, John W., Nayfield, Susan G., Schmader, Kenneth, Tian, Ying, Ashworth, John R., Clayton, Charles P., Parker, Ryan P., Tarver, Erika D., Woolard, Nancy F., High, Kevin P.·2009·Journal of the American Society of Nephrology

DOI 10.1681/asn.2008080860

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Abstract

Chronic kidney disease is a large and growing problem among aging populations. Although progression of chronic kidney disease to end-stage renal disease (ESRD) is a costly and important clinical event with substantial morbidity, it appears less frequently in aging people compared with cardiovascular mortality. The measurement of kidney function and management of kidney disease in older individuals remain challenging, partly because the pathophysiologic mechanisms underlying age-related decline in kidney function, the interactions between age and other risk factors in renal progression, and the associations of chronic kidney disease with other comorbidities in older people are understudied and poorly understood. The Association of Specialty Professors, the American Society of Nephrology, the American Geriatrics Society, the National Institute on Aging, and the National Institute of Diabetes and Digestive and Kidney Diseases held a workshop, summarized in this article, to review what is known about chronic kidney disease, identify research gaps and resources available to address them, and identify priority areas for future research. Answers to emerging research questions will support the integration of geriatrics and nephrology and thus improve care for older patients at risk for chronic kidney disease.

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Authors: Anderson, S., Halter, J. B., Hazzard, W. R., Himmelfarb, J., Horne, F. M., Kaysen, G. A., Kusek, J. W., Nayfield, S. G., Schmader, K., Tian, Y., Ashworth, J. R., Clayton, C. P., Parker, R. P., Tarver, E. D., Woolard, N. F., & High, K. P.
Affiliations: Oregon Health & Science University (US)
Corresponding author: High, Kevin P.
ORCID: Himmelfarb, Jonathan
Schmader, Kenneth
Tian, Ying
Woolard, Nancy F.
Venue: Journal of the American Society of Nephrology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2009-06
Volume: 20
Issue: 6
Pages: 1199-1209
ISSN: 1046-6673 (ISSN-L)
DOI: 10.1681/asn.2008080860
OpenAlex: W2168713667
Cited by: 218
References: 146
Citations by year: 2026: 1 · 2025: 6 · 2024: 12 · 2023: 10 · 2022: 10 · 2021: 15 · 2020: 16 · 2019: 14 · 2018: 15 · 2017: 19 · 2016: 19 · 2015: 16 · 2014: 6 · 2013: 15 · 2012: 10
FWCI: 9.91
Type: journal article
Language: en
Open access: closed
Locations: Journal of the American Society of Nephrology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (P30AG028716)
Topics: Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
Keywords: chronic kidney disease, older adults, aging, end-stage renal disease, renal function decline, comorbidities, kidney disease progression, geriatric nephrology, research priorities
MeSH terms: Aged, Aging, Cardiovascular Diseases, Humans, Comorbidity, Disease Progression, Biomedical Research, Renal Insufficiency, Chronic, Acute Kidney Injury

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. Prediction, progression and outcomes of chronic kidney disease in older adults.

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