Investigating the Effect of Microalgae Bioactive Compounds on Sleep and Mood
Open accessAbstract
Introduction: Nowadays, lack of sleep has led to many serious health problems. Meanwhile, cyanobacteria exhibit bioactive properties such as anti-inflammatory, anti-cancer, anti-bacterial, anti-parasitic, anti-diabetic, anti-viral, antioxidant, rejuvenating and anti-obesity, making them a suitable option for the production of drugs. Sleep and mental health are closely related, and the negative impact of sleep deprivation on overall health and well-being is exacerbated. Methods: In this review article, more than 200 journals on databases such as PubMed, Springer, Wiley، Science Direct, Scopus, Web of Sciences, and the list of open access journals were investigated. Keywords such as "microalgae", "bioactive compounds", "unsaturated fatty acids", "sleep disorders", "mood regulation" and "stress" were used for searching. Results: The results showed that sleep and mental health are closely related, and the negative effect of sleep deprivation on health and overall well-being intensifies is exacerbated. Conventional treatments have a wide range of adverse effects, commonly associated with benzodiazepines and antidepressants. Conclusion: At present, the significant contribution of microalgae bioactive compounds in sleep management and mental health has not been investigated, which is suggested to be widely studied in the near future.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Microalgal bioactives such as omega-3 PUFAs and carotenoids may exert neuroprotective and mood-regulating effects via modulation of neuroinflammation and oxidative stress pathways.
“microalgal bioactives such as omega-3 PUFAs and carotenoids may exert neuroprotective and mood-regulating effects via the modulation of neuroinflammation and oxidative stress pathways, although more targeted trials are needed [72].”
From Microalgae Bioactives for Functional Food Innovation and Health Promotion (2025) · cites this paper as [72]
The matching passages in the References and Additional information sections are bibliographic entries, not statements of the paper’s findings. Searches for omega-3 PUFAs, carotenoids, neuroprotection, neuroinflammation, oxidative stress, and mood regulation found no passage in our copy that states the proposed effects or mechanisms. (LLM, conf=0.69)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The publisher hasn’t deposited this paper’s reference list.
Research works printed but not linked: 7
- -Cobb RJ, Sheehan CM, Nguyen AW, Johnson D. COVID-19 Hardships and Self-Reported Sleep Quality among American Adults in March and April 2020: Results from a Nationally Representative Panel Study. Sleep Health 2022; 8(3): 288-93.
- -Nobis A, Zalewski D, Waszkiewicz N. Peripheral Markers of Depression. J Clin Med 2020; 9(12): 3793.
- -Bellahcen TO, AAmiri A, Touam I, Hmimid F, Amrani AE, Cherif A, et al. Evaluation of Moroccan Microalgae: Spirulina Platensis as a Potential Source of Natural Antioxidants. J Complement Integr Med 2020; 17(3): 20190036.
- -Schreiber S, Pick C. Trazodone and Mirtazapine: A Possible Opioid Involvement in their Use (At Low Dose) for Sleep? Med Hypotheses 2020; 136: 109501.
- -McCarthy B, O'Neill G, Abu-Ghannam N. Potential Psychoactive Effects of Microalgal Bioactive Compounds for the Case of Sleep and Mood Regulation: Opportunities and Challenges. Mar Drugs 2022; 20(8): 493.
- -Anvar A, Nowruzi B. Bioactive Properties of Spirulina: A Review. Microb Bioact 2021; 4: 134-42.
- -Hannan MA, Sohag AAM, Dash R, Haque MN, Mohibbullah M, Oktaviani DF, et al. Phytosterols of Marine Algae: Insights Into the Potential Health Benefits and Molecular Pharmacology. Phytomedicine 2020; 69: 153201. [ DOI: 10.18502/ssu.v32i7.16564 ] [ Downloaded from jssu.ssu.ac.ir on 2024-10-21 ]
Cited by
Sorted by citations
Microalgae Bioactives for Functional Food Innovation and Health Promotion
Guil-Guerrero, J. L., & Prates, J. A. M. (2025) · Foods · doi:10.3390/foods14122122 · Cited by 47 · see citing works
“A recent clinical review highlighted that microalgal bioactives such as omega-3 PUFAs and carotenoids may exert neuroprotective and mood-regulating effects via the modulation of neuroinflammation and oxidative stress pathways, although more targeted trials are needed [72].”
- Authors
- Nowruz, B.
- Affiliations
- Islamic Azad University, Tehran (IR)
- Corresponding author
- Nowruz, Bahareh
- Venue
- Journal of Shahid Sadoughi University of Medical Sciences
- Publisher
- Knowledge E DMCC
- Published
- 2024-09-29
- ISSN
- 2228-5733 (ISSN-L)
- 2228-5741
- OpenAlex
- W4402960901
- Cited by
- 1
- References
- 0
- Citations by year
- 2025: 1
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc
- Locations
- ماهنامه علمی پژوهشی دانشگاه علوم پزشکی شهید صدوقی یزد (publishedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Keywords
- microalgae, cyanobacteria, bioactive compounds, sleep disorders, sleep deprivation, mood regulation, mental health, unsaturated fatty acids, stress, antioxidant activity, anti-inflammatory activity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
