Peripheral oxytocin treatment ameliorates obesity by reducing food intake and visceral fat mass
Maejima, Yuko, Iwasaki, Yusaku, Yamahara, Yui, Kodaira, Misato, Sedbazar, Udval, Yada, Toshihiko·2011·Aging
Cited by (221)
Items 101–200 of 221
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- The adaptation of maternal energy metabolism to lactation and its underlying mechanismsGabriel Forato Anhê, Silvana Auxiliadora Bordin · 2022 · Molecular and Cellular Endocrinology
- Oxytocin levels are lower in premenopausal women with type 1 diabetes mellitus compared with matched controlsAmber S. Kujath, Lauretta T. Quinn, Mary Ellen Elliott, Krista A Varady, Tamara J. LeCaire, Carol Sue Carter, Kirstie K. Danielson · 2014 · Diabetes/Metabolism Research and Reviews
- Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulationBoyang Zhang, Masanori Nakata, Jun Nakae, Wataru Ogawa, Toshihiko Yada · 2018 · Scientific Reports
- Pathophysiological function of oxytocin secreted by neuropeptides: A mini reviewHirofumi Hashimoto, Yasuhito Uezono, Yoichi Ueta · 2012 · Pathophysiology
- Oxytocin therapy in hypopituitarism: Challenges and opportunitiesRaghav Bhargava, Katie Daughters, Aled Rees · 2018 · Clinical Endocrinology
- Chronic hindbrain administration of oxytocin elicits weight loss in male diet-induced obese miceMélise Marie Edwards, Ha K. Nguyen, Adam Jay Herbertson, Andrew Dale Dodson, Tomasz Wietecha, Tami Wolden‐Hanson, James Lawrence Graham, Kevin D. O’Brien, Peter Joseph Havel, James Ernest Blevins · 2021 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Oxytocin receptor gene polymorphism and low serum oxytocin level are associated with hyperphagia and obesity in adolescentsGönül Çatlı, Sezer Acar, Gülten Cingöz, Khayala Rasulova, Ayça KANAT YARIM, Hamide Uzun, Tuncay Küme, Sefa Kızıldağ, Bumin Nuri Dündar, Ayhan Abacı · 2021 · International Journal of Obesity
- Intranasal oxytocin reduces weight gain in diet-induced obese prairie volesAdele M. H. Seelke, Maya A. Rhine, Konterri Khun, Amira N. Shweyk, Alexandria M. Scott, Jessica M. Bond, James Lawrence Graham, Peter Joseph Havel, Tami Wolden‐Hanson, Karen Lisa Bales et al. · 2018 · Physiology & Behavior
- Intravenous administration of oxytocin in rats acutely decreases deprivation-induced chow intake, but it fails to affect consumption of palatable solutionsAnica Klockars, Chloe Brunton, Lu Li, Allen S. Levine, Pawel K. Olszewski · 2017 · Peptides
- Is weight status associated with peripheral levels of oxytocin? A pilot study in healthy women.Janelle A. Skinner, Manohar L. Garg, Christopher V. Dayas, Tracy L. Burrows · 2019 · Physiology & Behavior
- The relationship between oxytocin, dietary intake and feeding: A systematic review and meta-analysis of studies in mice and ratsJanelle A. Skinner, Erin J. Campbell, Christopher V. Dayas, Manohar L. Garg, Tracy L. Burrows · 2018 · Frontiers in Neuroendocrinology
- Disrupted Oxytocin-Appetite Signaling in Females With Anorexia NervosaAnna Aulinas, Franziska Plessow, Reitumetse Pulumo, Elisa Asanza, Christopher J. Mancuso, Meghan J. Slattery, Christiane Tolley, Jennifer J. Thomas, Kamryn T. Eddy, Karen Klahr Miller et al. · 2019 · The Journal of Clinical Endocrinology & Metabolism
- Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male MicePoonamjot Deol, Elena V. Kozlova, Matthew Christopher Valdez, Catherine Ho, Ei-Wen Yang, Holly Richardson, Gwendolyn Michelle Gonzalez, Edward Truong, Jack Reid, Joseph M. Valdez et al. · 2020 · Endocrinology
- Effect of Oxytocin on Hunger DiscriminationMitchell A. Head, David C. Jewett, Sarah N. Gartner, Anica Klockars, Allen S. Levine, Pawel K. Olszewski · 2019 · Frontiers in Endocrinology
- Changes in Endogenous Oxytocin Levels and the Effects of Exogenous Oxytocin Administration on Body Weight Changes and Food Intake in Polycystic Ovary Syndrome Model RatsShota Yamamoto, Hiroki Noguchi, Asuka Takeda, Ryosuke Arakaki, Maimi Uchishiba, Junki Imaizumi, Saki Minato, Shuhei Kamada, Tomohiro Kagawa, Atsuko Yoshida et al. · 2022 · International Journal of Molecular Sciences
- Fasted/fed states regulate postsynaptic hub protein DYNLL2 and glutamatergic transmission in oxytocin neurons in the hypothalamic paraventricular nucleusShigetomo Suyama, Misato Hirano-Kodaira, Zesemdorj Otgon-Uul, Yoichi Ueta, Masanori Nakata, Toshihiko Yada · 2015 · Neuropeptides
- Oxytocin Administration Alleviates Acute but Not Chronic Leptin Resistance of Diet-Induced Obese MiceMehdi Labyb, Claire Chrétien, Aurélie Caillon, Françoise Rohner‐Jeanrenaud, Jordi Altirriba · 2018 · International Journal of Molecular Sciences
- The effects of chronic oxytocin administration on body weight and food intake in DHT-induced PCOS model ratsTakeshi Iwasa, Toshiya Matsuzaki, Yiliyasi Mayila, Takako Kawakita, Rie Yanagihara, Minoru Irahara · 2019 · Gynecological Endocrinology
- Oxytocin projections to the nucleus of the solitary tract contribute to the increased meal‐related satiety responses in primary adrenal insufficiencyErnane Torres Uchôa, Daniel S. Zahm, Beatriz C. Borges, Rodrigo Cesar Rorato, José Antunes‐Rodrigues, Lucila Leico Kagohara Elias · 2013 · Experimental Physiology
- Recent progress in the pharmacotherapy for obesityLu, Jiale, Liu, Pengfei, Cai, Mengyang, Lv, Tongzhe, Zhang, Mengdi, Yin, Kaili, Cheng, Jie, Zhang, Guo · 2025 · European Journal of Pharmacology
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- Oxytocin and the microbiomeSusan E. Erdman · 2021 · Current Opinion in Endocrine and Metabolic Research
- Understanding oxytocin in human physiology and pathophysiology: A path towards therapeuticsElizabeth Austen Lawson · 2024 · Comprehensive Psychoneuroendocrinology
- Neuroendocrine drivers of risk and resilience: The influence of metabolism & mitochondriaSusie Turkson, Alex Kloster, Peter J. Hamilton, Gretchen N. Neigh · 2019 · Frontiers in Neuroendocrinology
- Oxytocin: An Old Hormone, a Novel Psychotropic Drug and its Possible Use in Treating Psychiatric DisordersDonatella Marazziti, Phuoc-Tan Diep, Carol Sue Carter, Manuel Glauco Carbone · 2022 · Current Medicinal Chemistry
- Cross-sectional correlates of increased IL-18 but reduced fetuin-A and oxytocin with adiposity and blood indices in metabolic syndrome patients with and without prediabetesViolet N. Kasabri, Esraa Shawakri, Amal A. Akour, Randa G. Naffa, Nahla M. Khawaja, Ibrahim Al-Sarraf, Jameel Bzour · 2018 · Therapeutic Advances in Endocrinology and Metabolism
- Effects of peripheral oxytocin administration on body weight, food intake, adipocytes, and biochemical parameters in peri- and postmenopausal female ratsOtgontsetseg Erdenebayar, Takeshi Kato, Takako Kawakita, Kana Kasai, Yuri Kadota, Kanako Yoshida, Takeshi Iwasa, Minoru Irahara · 2020 · Endocrine Journal
- Effects of Combined Oxytocin and Beta-3 Receptor Agonist (CL 316243) Treatment on Body Weight and Adiposity in Male Diet-Induced Obese RatsMélise Marie Edwards, Ha K. Nguyen, Andrew Dale Dodson, Adam Jay Herbertson, Tomasz Wietecha, Tami Wolden‐Hanson, James Lawrence Graham, Mackenzie K. Honeycutt, Jared D. Slattery, Kevin D. O’Brien et al. · 2021 · Frontiers in Physiology
- Oxytocin as a potential pharmacological tool to combat obesityPawel K. Olszewski, Emily E. Noble, Luis Paiva, Yoichi Ueta, James Ernest Blevins · 2022 · Journal of Neuroendocrinology
- Microbes, oxytocin and stress: Converging players regulating eating behaviorCristina Cuesta‐Marti, Friederike Uhlig, Begoña Muguerza, Niall P. Hyland, Gerard A. Clarke, Harriët Schellekens · 2023 · Journal of Neuroendocrinology
- The Neural Network of Neuropeptide S (NPS): Implications in Food Intake and Gastrointestinal FunctionsLuca Botticelli, Emanuela Micioni Di Bonaventura, Massimo Ubaldi, Roberto Ciccocioppo, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura · 2021 · Pharmaceuticals
- Early Life Stress, Brain Development, and Obesity Risk: Is Oxytocin the Missing Link?Georgia Colleluori, Chiara Galli, Ilenia Severi, Jessica Perugini, Antonio Giordano · 2022 · Cells
- The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic healthAdriano Winterton, Francesco Bettella, Dani Beck, Tiril Pedersen Gurholt, Nils Eiel Steen, Linn Nilsen Rødevand, Lars Tjelta Westlye, Ole A. Andreassen, Daniel S. Quintana · 2022 · Psychoneuroendocrinology
- Hippocampus Oxytocin Signaling Promotes Prosocial Eating in RatsJessica J. Rea, Clarissa M. Liu, Anna Hayes, Alexander G. Bashaw, Grace M. Schwartz, Rita Ohan, Léa Décarie-Spain, Alicia E. Kao, Molly E. Klug, Kenneth J. Phung et al. · 2024 · Biological Psychiatry
- Review of eating disorders and oxytocin receptor polymorphismsVictoria Burmester, Dasha Nicholls, Alexis Buckle, Boban Stanojević, Marta Crous‐Bou · 2021 · Journal of Eating Disorders
- A randomized, double-blind, placebo-controlled clinical trial of 8-week intranasal oxytocin administration in adults with obesity: Rationale, study design, and methodsMarie‐Louis Wronski, Franziska Plessow, Liya Kerem, Elisa Asanza, Michelle L. O’Donoghue, Fatima Cody Stanford, Miriam A. Bredella, Martin Torriani, Alexander A. Soukas, Arvin Kheterpal et al. · 2022 · Contemporary Clinical Trials
- Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effectsMohammed Asker, Jean‐Philippe Krieger, Amber Liles, Ian C. Tinsley, Tito Borner, Ivana Marić, Sarah A. Doebley, C. Daniel Furst, Stina Börchers, Francesco Longo et al. · 2022 · Diabetes Obesity and Metabolism
- Involvement of central nesfatin-1 neurons on oxytocin-induced feeding suppression in ratsReiko Saito, Satomi Sonoda, Hiromichi Ueno, Yasuhito Motojima, Mitsuhiro Yoshimura, Takashi Maruyama, Hirofumi Hashimoto, Kentaro Tanaka, Yukiyo Yamamoto, Koichi Kusuhara et al. · 2017 · Neuroscience Letters
- Identification of oxytocin receptor activating chemical components from traditional Japanese medicinesYuko Maejima, Shoichiro Horita, Shoko Yokota, Tomoyuki Ono, Peter Proks, Hiromi Yoshida‐Komiya, Yoichi Ueta, Katsuhiko Nishimori, Shingen Misaka, Kenju Shimomura · 2021 · Journal of Food and Drug Analysis
- Oxytocin: A Potential Therapeutic for ObesitySoo Min Hong, Jeong-Kyung Ko, Jung‐Joon Moon, Youl‐Ri Kim · 2021 · Journal of Obesity & Metabolic Syndrome
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- Hindbrain Administration of Oxytocin Reduces Food Intake, Weight Gain and Activates Catecholamine Neurons in the Hindbrain Nucleus of the Solitary Tract in RatsVishwanath T. Anekonda, Benjamin W. Thompson, Jacqueline M. Ho, Zachary S. Roberts, Mélise Marie Edwards, Ha K. Nguyen, Andrew Dale Dodson, Tami Wolden‐Hanson, Daniel W. Chukri, Adam Jay Herbertson et al. · 2021 · Journal of Clinical Medicine
- Oxytocin signal contributes to the adaptative growth of islets during gestationPing Gu, Yuege Lin, Qi Wan, Dongming Su, Qun Shu · 2021 · Endocrine Connections
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- Vagal oxytocin receptors are necessary for esophageal motility and functionMohammed Asker, Jean-Philippe Krieger, Ivana Marić, Emre Bedel, Jenny Theodora van der Steen, Stina Börchers, Yuxiang Wen, Francesco Longo, Patrik Aronsson, Michael Winder et al. · 2025 · JCI Insight
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- Beneficial Dog Bacteria Up-Regulate Oxytocin and Lower Risk of ObesityBernard J. Varian, Tatiana Levkovich, Theofilos Poutahidis, Yassin M. Ibrahim · 2017 · Journal of Probiotics & Health
- Robust Reductions of Body Weight and Food Intake by an Oxytocin Analog in RatsClinton Elfers, James Ernest Blevins, Elizabeth Austen Lawson, Richard A. Pittner, David Silva, Alex S. Kiselyov, Christian Ludwig Roth · 2021 · Frontiers in Physiology
- Oestrogen-dependent hypothalamic oxytocin expression with changes in feeding and body weight in female ratsKazuaki Nishimura, Kiyoshi Yoshino, Naofumi Ikeda, Kazuhiko Baba, Kenya Sanada, Yasuki Akiyama, Haruki Nishimura, Kentaro Tanaka, Satomi Sonoda, Hiromichi Ueno et al. · 2022 · Communications Biology
- Systemic Co-Administration of Low-Dose Oxytocin and Glucagon-Like Peptide 1 Additively Decreases Food Intake and Body WeightYuko Maejima, Shoko Yokota, Shizu Hidema, Katsuhiko Nishimori, Heidi de Wet, Kenju Shimomura · 2024 · Neuroendocrinology
- Sex differences in the effects of aromatherapy on anxiety and salivary oxytocin levelsDaisuke Nakajima, Megumi Yamachi, Shingen Misaka, Kenju Shimomura, Yuko Maejima · 2024 · Frontiers in Endocrinology
- Effect of combination of peripheral oxytocin and naltrexone at subthreshold doses on food intake, body weight and feeding-related brain gene expression in male ratsMitchell A. Head, Allen S. Levine, David G. Christian, Anica Klockars, Pawel K. Olszewski · 2021 · Physiology & Behavior
- The OXTR Polymorphism Stratified the Correlation of Oxytocin and Glucose Homeostasis in Non-Diabetic SubjectsHui Hua Chang, Wei Hung Chang, Mei Hung Chi, Yi Peng, Chih-Chun Jean Huang, Yen Kuang Yang, Po See Chen · 2019 · Diabetes Metabolic Syndrome and Obesity
- Increased oxytocin release precedes hyponatremia after pituitary surgeryPaul Eugène Constanthin, Nathalie Isidor, Sophie de Seigneux, Shahan Momjian · 2021 · Pituitary
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- Vagal Oxytocin Receptors as Molecular Targets in Gut–Brain Signaling: Implications for Appetite, Satiety, Obesity, and Esophageal Motility—A Narrative ReviewAgnieszka Nowacka, Maciej Śniegocki, Ewa Ziółkowska · 2025 · International Journal of Molecular Sciences
- Interactions Between the Neuroendocrine System and T Lymphocytes in DiabetesLuz Andreone, María Laura Gimeno, Marcelo Javier Perone · 2018 · Frontiers in Endocrinology
- Engineering a Potent, Long-Acting, and Periphery-Restricted Oxytocin Receptor Agonist with Anorexigenic and Body Weight Reducing EffectsElsa Pflimlin, Zhihong Zhou, Zaid Amso, Qiangwei Fu, Candy Lee, Avinash Muppidi, Sean B. Joseph, Vân T. B. Nguyen-Tran, Weijun Shen · 2019 · Journal of Medicinal Chemistry
- Oral oxytocin delivery with proton pump inhibitor pretreatment decreases food intakeYuko Maejima, Shoichiro Horita, Ayano Otsuka, Shizu Hidema, Katsuhiko Nishimori, Kenju Shimomura · 2020 · Peptides
- Oxytocin participates on the effects of vasoactive intestinal peptide on food intake and plasma parametersAndressa Busetti Martins, Marcela Cristina Garnica-Siqueira, Dimas Augusto Morozin Zaia, Cássia Thaïs Bussamra Vieira Zaia, Ernane Torres Uchôa · 2017 · Molecular and Cellular Biochemistry
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- Oxytocin neurons in the paraventricular and supraoptic hypothalamic nuclei bidirectionally modulate food intakeJessica J. Rea, Clarissa M. Liu, Anna Hayes, Rita Ohan, Grace M. Schwartz, Alexander G. Bashaw, Molly E. Klug, Léa Décarie-Spain, Yedam Park, Alicia E. Kao et al. · 2025 · Molecular Metabolism
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- Unchanged food approach‐avoidance behaviour of healthy men after oxytocin administrationAnna Melkonyan, Lu Liu, Elliot Clayton Brown, Willi Meyer, Apoorva Rajiv Madipakkam, Lina Ringelmann, Franziska Lange, Sebastian Michael Schmid, Thomas Frank Münte, Soyoung Q. Park · 2020 · Journal of Neuroendocrinology
- Relationship between Oxytocin and Osteoarthritis: Hope or Despair?Stephanie Ferrero, Ez‐Zoubir Amri, Christian Hubert Roux · 2021 · International Journal of Molecular Sciences
- Insulin-regulated aminopeptidase in adipocyte is Cys-specific and affected by obesityRafaela Fadoni Alponti, Luciana Godoy Viana, Norma Yamanouye, Paulo Flávio Silveira · 2015 · Journal of Molecular Endocrinology
- Novel adipocyte aminopeptidases are selectively upregulated by insulin in healthy and obese ratsRafaela Fadoni Alponti, Patricia Lucio Alves, Paulo Flávio Silveira · 2015 · Journal of Endocrinology
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- Effects of systemic oxytocin and beta‐3 receptor agonist (CL 316243) treatment on body weight and adiposity in male diet‐induced obese ratsJared D. Slattery, June R. Rambousek, Edison W. Tsui, Mackenzie K. Honeycutt, Matvey Goldberg, James Lawrence Graham, Tomasz Wietecha, Tami Wolden‐Hanson, Amber L. Williams, Kevin D. O’Brien et al. · 2025 · Frontiers in Endocrinology
- Corticotrophin-releasing factor receptor 2 mediates the enhanced activation of satiety-related responses through oxytocin neurons in the paraventricular nucleus of the hypothalamus after adrenalectomyErnane Torres Uchôa, Rodrigo Cesar Rorato, Sílvia Graciela Ruginsk, Beatriz C. Borges, José Antunes‐Rodrigues, Lucila Leico Kagohara Elias · 2015 · Neuroscience Letters
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