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Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization

Roblain, Quentin, Louis, Thomas, Yip, Cassandre, Baudin, Louis, Struman, Ingrid, Caolo, Vincenza, Lambert, Vincent, Lecomte, Julie +2 more·2021·Aging

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  • miR-7 regulates neuronal death and glutamatergic signaling; miR-137 is critical for neural development; miR-935 and miR-129-2-3p are elevated in epileptic brains and plasma.

    “miR-7 regulates neuronal death and glutamatergic signaling 40,41 ; miR-137 is critical for neural development 42 ; miR-935 and miR-129-2-3p are both elevated in epileptic brains and plasma 43 .”

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Authors
Roblain, Q., Louis, T., Yip, C., Baudin, L., Struman, I., Caolo, V., Lambert, V., Lecomte, J., Noël, A., & Heymans, S.
Affiliations
  • Laboratory of Tumor and Development Biology, GIGA-Cancer, University of Liège, Liège, Belgium
  • Molecular Angiogenesis Laboratory, GIGA-Cancer, University of Liège, Liège, Belgium
  • Department of Cardiovascular Sciences, Centre for Molecular and Vascular Biology, KU Leuven, Leuven, Belgium
  • Department of Cardiology, CARIM School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
Venue
Aging
Published
2021-05-05
Volume
13
Issue
9
Pages
12359-12377
ISSN
1945-4589
Cited by
25
References
2
Language
en

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