Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

Eling, Nils, Reuter, Lukas, Hazin, John, Hamacher-Brady, Anne, Brady, Nathan R.·2015·Oncoscience

Cited by (530)

Items 401–500 of 530

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  6. Epigenetic Regulation and Nonepigenetic Mechanisms of Ferroptosis Drive Emerging Nanotherapeutics in Tumor
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  7. A New Ferroptosis-Related Long Non-Coding RNA Risk Model Predicts the Prognosis of Patients With Papillary Thyroid Cancer
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  8. Epigenetic regulation of ferroptosis in gastrointestinal cancers (Review)
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  9. Ferroptosis’s Master Switch GPX4 emerges as universal biomarker for precision immunotherapy: a pan-cancer study with in vitro experiments validation
    Xiao Li, Min Zhu, Ruihua Dong · 2025 · Frontiers in Oncology
  10. The Role of Artesunate in Cancer Management: Mechanisms of Biomedical Effects and Toxicology
    J F Li, Jing Zheng, Yue Cui, Yang Liu, Huixia Fan, Xinyu Wang, Huan Liu, Xueyan Li, Guohua Yu, Zhiqiang Luo · 2025 · The American Journal of Chinese Medicine
  11. Downregulation of ALDH5A1 suppresses cisplatin resistance in esophageal squamous cell carcinoma by regulating ferroptosis signaling pathways
    Kewei Song, Chenhui Ma, Ewetse Paul Maswikiti, Baohong Gu, Bofang Wang, Na Wang, Pei Jiang, Hao Chen · 2024 · Molecular Carcinogenesis
  12. Markers of oxidative‐nitrosative stress induced by artesunate are followed by clastogenic and aneugenic effects and apoptosis in human lymphocytes
    Tatiane Cristina Mota, Tarcyane Barata Garcia, Laís Teixeira Bonfim, Adrhyann Jullyanne de Sousa Portilho, Camila Albuquerque Pinto, Rommel Mário Rodríguez Burbano, Marcelo de Oliveira Bahia · 2019 · Journal of Applied Toxicology
  13. Small Molecule Regulators of Ferroptosis
    Sylvain Debieu, Stéphanie Solier, Ludovic Colombeau, Antoine Versini, Fabien Sindikubwabo, Alison R. Forrester, Sebastian Müller, Tatiana Cañeque, Raphaël Rodriguez · 2021 · Advances in experimental medicine and biology
  14. Ferroptosis-Related Long Noncoding RNA Signature Predicts Prognosis of Clear Cell Renal Carcinoma
    J. W. Liu, Farahaniza Supandi, Sarinder Kaur Dhillon · 2022 · Folia Biologica
  15. Construction and validation of a predictive nomogram for ferroptosis-related genes in osteosarcoma
    Jinzhi Meng, Huawei Du, Jinfeng Lü, Hongtao Wang · 2023 · Journal of Cancer Research and Clinical Oncology
  16. Genome, Metabolism, or Immunity: Which Is the Primary Decider of Pancreatic Cancer Fate through Non-Apoptotic Cell Death?
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  17. Immunization Combined with Ferroptosis Related Genes to Construct a New Prognostic Model for Head and Neck Squamous Cell Carcinoma
    Linhui Yang, Zhiwei Chen, Yunliang Liu, Xiaoyan Wang, Jing Li, Qing Ye · 2022 · Cancers
  18. The crucial value of serum ferritin in assessing high-risk factors and prognosis for patients with endometrial carcinoma
    Jiali Liu, Beibei Xuan, Quan Quan, Sainan Gong, Xiaoling Mu · 2023 · BMC Women s Health
  19. Development of a lysosome-targeted probe for revealing the fluctuations of the intracellular hypochlorous acid (HClO) during ferroptosis
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  20. Deciphering Ferroptosis: From Molecular Pathways to Machine Learning-Guided Therapeutic Innovation
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  21. Ferroptosis Resistance in Cancer: An Emerging Crisis of New Hope
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  22. Iron metabolism in prostate cancer
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  23. Emerging roles and therapeutic potentials of ferroptosis: from the perspective of 11 human body organ systems
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  24. The Antimalarial Drug Artesunate Mediates Selective Cytotoxicity by Upregulating HO-1 in Melanoma Cells
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  25. Clusterin is upregulated by erastin, a ferroptosis inducer and exerts cytoprotective effects in pancreatic adenocarcinoma cells
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  26. Identification and validation of stemness-based and ferroptosis-related molecular clusters in pancreatic ductal adenocarcinoma
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  27. Current understanding of phytochemicals from Chinese herbal medicines for ferroptosis-mediated cancer prevention and treatment
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  29. Artesunate and chloroquine induce cytotoxic activity on cholangiocarcinoma cells via different cell death mechanisms
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  30. Ferroptosis in Nervous System Diseases
    Jieru Wan, Xiuli Yang, Jian Wang · 2019 · Springer eBooks
  31. Ferroptosis in cancer: integrating multi-omics, AI-driven biomarkers, and translational challenges
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  32. YM155, specific survivin inhibitor, can enhance artesunate-induced cytotoxicity in HCT116 colon cancer cells
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  33. IDH1 Mutation Impacts DNA Repair Through ALKBH2 Rendering Glioblastoma Cells Sensitive to Artesunate
    Olivier J. Switzeny, Stefan Pusch, Markus Christmann, Bernd Kaina · 2025 · Biomedicines
  34. Ferroptosis-related lncRNAs guiding osteosarcoma prognosis and immune microenvironment
    Mingyi Yang, Yani Su, Ke Xu, Haishi Zheng, Qiling Yuan, Yongsong Cai, Yirixiati Aihaiti, Peng Xu · 2023 · Journal of Orthopaedic Surgery and Research
  35. Recent research progress based on ferroptosis-related signaling pathways and the tumor microenvironment on it effects
    Shijing Yu, Ling-Wu Tong, Jiangwen Shen, Chenglei Li, Yongshan Hu, Ke-Ke Feng, Jingwei Shao · 2024 · European Journal of Medicinal Chemistry
  36. Chronic Inflammation in Asthma
    Thai Tran, Yongkang Qiao, Huihui You, Dorothy Hui Juan Cheong · 2017 · Elsevier eBooks
  37. Drug Combination Antagonism and Single Agent Dominance Result from Differences in Death Activation Kinetics
    Ryan Richards, Hannah R. Schwartz, Mariah S. Stewart, Peter Cruz‐Gordillo, Megan E. Honeywell, Anna J. Joyce, Benjamin D. Landry, Michael J. Lee · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  38. Cell Membrane Biomimetic Drug Delivery Systems Based on Ferroptosis Mechanism for Anticancer Treatment
    Li Su, Shuoye Yang, Huajian Yuan, Qianqian Cheng, Xin Wang, Ning Li, Lu Zhang, Peng Li · 2025 · Advanced Healthcare Materials
  39. Ferrocenyl ferroptosis inducers as an emerging class of anticancer agents: a mini review
    Mateusz Klarek, Aryan Gautam, Konrad Kowalski · 2025 · RSC Medicinal Chemistry
  40. Cell Injury and Necrosis
    Joana C. d’Avila, Stuart Levin, Z.A. Radi · 2017 · Elsevier eBooks
  41. Yeni Bir Hücre Ölüm Şekli Olarak Ferroptozis
    Alper Çelenk · 2021 · Arşiv Kaynak Tarama Dergisi
  42. Bioinformatics analysis identifies ferroptosis‑related genes in the regulatory mechanism of myocardial infarction
    Yong-Hao Jiang, Su‐Ying Wu, Zhen Wang, Lei Zhang, Juan Zhang, Yan Li, Chenglong Liu, Wenzhe Wu, Yitao Xue · 2022 · Experimental and Therapeutic Medicine
  43. Pharmacological Targeting of Ferroptosis in Cancer Treatment
    Mohammad Altaf Khan, Trilochan Satapathy, Kalpana Sen, Shailesh Sahu, Bharti Pradhan, Ayushi Gupta, Abinash Satapathy, Ansuman Satapathy · 2024 · Journal of Drug Delivery and Therapeutics
  44. The Role of Redox Environment in Tumors
    Jiaping Wu, Liling Hu, Wei Liu, Xiaowen Liu, Jun Jie Zheng, Xiao Tan · 2024 · Current Medicinal Chemistry
  45. Induction of programmed necrosis by phytochemicals in colorectal cancer
    Jie Zhong Yu, Bingling Zhong, Xiuping Chen · 2020 · Elsevier eBooks
  46. Natural compounds and programmed necrosis: pioneering a new frontier in cancer treatments
    Md. Al Amin, Hasna Bouhenni, Mehrukh Zehravi, Sherouk Hussein Sweilam, Trupti Pratik Durgawale, Mohammad Shamim Qureshi, Sumit Durgapal, M. Akiful Haque, Rajeshwar Vodeti, Deepadarshan Urs et al. · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
  47. Targeting Cellular Energetics via Ferroptosis Mediated Cell Death in Resistant Colorectal Cancer Stem Cells
    Tanika Biswas, Sumit Mallick, Utsav Sen, Debajit Chaudhury, Sudheer Shenoy P, Bipasha Bose · 2025 · BioFactors
  48. CTHRC1/TGF-β/Smad axis serves as therapeutic targets in inhibiting oral squamous cell carcinoma by mediating ferroptosis
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  51. DPP4 suppresses pancreatic cancer growth by enhancing ferroptosis sensitivity through stabilization of ACSL4
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  52. Frontiers of Ferroptosis in Cancer Treatment
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  53. Exploring a 7-gene prognostic model based on ferroptosis for efficiently guiding immunotherapy in melanoma patients
    Xin Zhang, Changrui Ding, Zigang Zhao · 2022 · Advances in Medical Sciences
  54. Identification of a ferroptosis-related gene signature for the prognosis of pediatric neuroblastoma
    Xijin Lin, Kongfeng Shao, Zhuangbin Lin, Qiandong Liang, Xiaoyan Li, Haiyan Chen, Junxin Wu · 2024 · Translational Cancer Research
  55. Visual analysis on ferroptosis and its cross-talk to coronavirus disease 2019 (COVID-19)
    Junda Zhou, Wenjia Ni, Xianqin Zhang, Meng Yang, Xin Liu, Jinlin Guo, Jian Li, Qi Zhao, Hang Deng, Hanyue Lei et al. · 2024 · Heliyon
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    Devinder Kumar, Uday C Ghoshal, Vamika Mansi Saigal, Moni Chaudhary, Shikha Sahu, Vishruti N. Pandya, Ujjala Ghoshal · 2025 · JGH Open
  57. Fucoidan induces ferroptosis in colorectal cancer cells by regulating the SLC7A11/GPX4 signaling pathway and modulating metabolic pathways
    Chengyu Yang, Chunqi Feng, Naiqi Zhang, Jia Feng, Shulian Xie, Xinghua Li, Qi Liu · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
  58. Study of a series of fluorophore-labeled artesunate derivatives – Design, analysis and application
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  97. Additional file 5 of Identification the ferroptosis-related gene signature in patients with esophageal adenocarcinoma
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  98. Additional file 4 of Identification the ferroptosis-related gene signature in patients with esophageal adenocarcinoma
    Zhu, Lei, Fugui Yang, Wang, Lingwei, Dong, Lin, Huang, Zhiyuan, Guangxue Wang, Guohan Chen, Qinchuan Li · 2021 · Figshare
  99. Additional file 6 of Identification the ferroptosis-related gene signature in patients with esophageal adenocarcinoma
    Zhu, Lei, Fugui Yang, Wang, Lingwei, Dong, Lin, Huang, Zhiyuan, Guangxue Wang, Guohan Chen, Qinchuan Li · 2021 · Figshare
  100. Additional file 2 of Identification the ferroptosis-related gene signature in patients with esophageal adenocarcinoma
    Lei Zhu, Fugui Yang, Wang, Lingwei, Dong, Lin, Huang, Zhiyuan, Guangxue Wang, Guohan Chen, Qinchuan Li · 2021 · Figshare