Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

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Items 201–300 of 530

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2. Silencing of PTPN18 Induced Ferroptosis in Endometrial Cancer Cells Through p-P38-Mediated GPX4/xCT Down-Regulation
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3. Impact of ferroptosis on preeclampsia: A review
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4. An Artemisinin‐Derivative–(NHC)Gold(I) Hybrid with Enhanced Cytotoxicity through Inhibition of NRF2 Transcriptional Activity
   Chen Zhang, Pierre‐Yves Fortin, Guillaume Barnoin, Xue Qin, Xing Wang, Álvaro Fernández Álvarez, Christian Bijani, Marie‐Lise Maddelein, Catherine Hemmert, Olivier Cuvillier et al. · 2020 · Angewandte Chemie International Edition
5. Molecular mechanisms of ferroptosis and its role in prostate cancer therapy
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6. Deciphering the potential roles of ferroptosis in regulating tumor immunity and tumor immunotherapy
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7. Understanding the Novel Approach of Nanoferroptosis for Cancer Therapy
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8. Ferroptosis in Low-Grade Glioma: A New Marker for Diagnosis and Prognosis
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9. The construction and analysis of a ferroptosis-related gene prognostic signature for pancreatic cancer
   Peicheng Jiang, Feng Yang, Caifeng Zou, Tianyuan Bao, Mengmeng Wu, Dongqin Yang, Shurui Bu · 2021 · Aging
10. A prognostic model for hepatocellular carcinoma patients based on signature ferroptosis-related genes
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11. Can Polyphenols Inhibit Ferroptosis?
    Marija M. Lesjak, Nataša Đ. Simin, Surjit Kaila Srai · 2022 · Antioxidants
12. Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis
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13. Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy
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14. HIF‑1α inhibits ferroptosis and promotes malignant progression in non‑small cell lung cancer by activating the Hippo‑YAP signalling pathway
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15. Drug antagonism and single-agent dominance result from differences in death kinetics
    Ryan Richards, Hannah R. Schwartz, Megan E. Honeywell, Mariah S. Stewart, Peter Cruz‐Gordillo, Anna J. Joyce, Benjamin D. Landry, Michael J. Lee · 2020 · Nature Chemical Biology
16. Irisin Is a Positive Regulator for Ferroptosis in Pancreatic Cancer
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17. CPEB1 enhances erastin‐induced ferroptosis in gastric cancer cells by suppressing twist1 expression
    Jing Wang, Tao Wang, Yang Zhang, Jiaqi Liu, Jie Song, Yanlong Han, Lihong Wang, Shuang Yang, Lili Zhu, Rui Geng et al. · 2021 · IUBMB Life
18. Lipid metabolism in ferroptosis and ferroptosis-based cancer therapy
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19. The selectivity of artemisinin-based drugs on human lung normal and cancer cells
    Xinyang Li, Shiyan Gu, Donglei Sun, Huangmei Dai, Hongyu Chen, Zunzhen Zhang · 2017 · Environmental Toxicology and Pharmacology
20. Caspase-Independent Regulated Necrosis Pathways as Potential Targets in Cancer Management
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21. The Evolving Role of Ferroptosis in Breast Cancer: Translational Implications Present and Future
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22. Current Advances in Photoactive Agents for Cancer Imaging and Therapy
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23. Functional role of ferroptosis on cancers, activation and deactivation by various therapeutic candidates-an update
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24. Redox Epiphospholipidome in Programmed Cell Death Signaling: Catalytic Mechanisms and Regulation
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25. A Novel lncRNA Panel Related to Ferroptosis, Tumor Progression, and Microenvironment is a Robust Prognostic Indicator for Glioma Patients
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26. JAK/STAT signaling and cellular iron metabolism in hepatocellular carcinoma: therapeutic implications
    Bilal Rah, Nada Mazen Farhat, Mawieh A. Hamad, Jibran Sualeh Muhammad · 2023 · Clinical and Experimental Medicine
27. Ferroptosis: Biology and Role in Gastrointestinal Disease
    Juan-José Escuder‐Rodríguez, Deguang Liang, Xuejun Jiang, Frank A. Sinicrope · 2024 · Gastroenterology
28. An endoplasmic reticulum-targeting fluorescent probe for the visualization of the viscosity fluctuations during ferroptosis in live cells
    Hua Wei, Xiaochan Tang, Qingxian Chen, Tao Yue, Baoli Dong · 2022 · Analytica Chimica Acta
29. Ferroptosis and metabolic syndrome and complications: association, mechanism, and translational applications
    Dongmei Zhou, Peipei Lu, Xianglai Mo, Bing Yang, Ting Chen, You Yao, Tian Xiong, Yue Lin, Xi Yang · 2024 · Frontiers in Endocrinology
30. Targeting ferroptosis for leukemia therapy: exploring novel strategies from its mechanisms and role in leukemia based on nanotechnology
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31. Unlocking ferroptosis in prostate cancer — the road to novel therapies and imaging markers
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32. Potential mechanism of ferroptosis in pancreatic cancer (Review)
    Gang Chen, Guangqi Guo, Xiaodong Zhou, Hongxia Chen · 2019 · Oncology Letters
33. DUSP1 Blocks autophagy-dependent ferroptosis in pancreatic cancer
    Yangchun Xie, Feimei Kuang, Jiao Liu, Daolin Tang, Rui Kang · 2020 · Journal of Pancreatology
34. Artemisinins in Combating Viral Infections Like SARS-CoV-2, Inflammation and Cancers and Options to Meet Increased Global Demand
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35. Ferroptosis Involvement in Glioblastoma Treatment
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36. Scutellaria barbata Inhibits Hepatocellular Carcinoma Tumorigenicity by Inducing Ferroptosis of Hepatocellular Carcinoma Cells
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37. The Relationship Between Ferroptosis and Diseases
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38. Traditional Chinese medicine may be further explored as candidate drugs for pancreatic cancer: A review
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39. Artemisinin–Second Career as Anticancer Drug?
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40. Artesunate Suppresses the Growth of Prostatic Cancer Cells through Inhibiting Androgen Receptor
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41. Artesunate induces ER-derived-ROS-mediated cell death by disrupting labile iron pool and iron redistribution in hepatocellular carcinoma cells.
    Zhongyong Jiang, Ziwen Wang, Long Chen, Chi Zhang, Fengying Liao, Yawei Wang, Yang Wang, Peng Luo, Min Luo, Chunmeng Shi · 2021 · PubMed Central
42. Construction of Ovarian Cancer Prognostic Model Based on the Investigation of Ferroptosis-Related lncRNA
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43. A guide to ferroptosis, the biological rust of cellular membranes
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44. The Role of Nrf2 in the Regulation of Mitochondrial Function and Ferroptosis in Pancreatic Cancer
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45. Adaptive Changes Allow Targeting of Ferroptosis for Glioma Treatment
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46. Progress in Redirecting Antiparasitic Drugs for Cancer Treatment
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47. A case–control study in Taiwanese cohort and meta-analysis of serum ferritin in pancreatic cancer
    Ji Min Park, Chen-Zou Mau, Yang‐Ching Chen, Yen‐Hao Su, Hsin An Chen, Shih‐Yi Huang, Jung‐Su Chang, Ching‐Feng Chiu · 2021 · Scientific Reports
48. Artesunate Inhibits the Growth Behavior of Docetaxel-Resistant Prostate Cancer Cells
    Olesya Vakhrusheva, Holger H.H. Erb, Vitus Braeunig, Sascha D. Markowitsch, Patricia Schupp, Patrick C. Baer, Kimberly Sue Slade, Anita Thomas, Igor Tsaur, Martin Puhr et al. · 2022 · Frontiers in Oncology
49. Elabela: Negative Regulation of Ferroptosis in Trophoblasts via the Ferritinophagy Pathway Implicated in the Pathogenesis of Preeclampsia
    Huan Yang, Xuemei Zhang, Yubin Ding, Hui Xiong, Hui Xiong, Yang Wang, Huanhuan Li, Huanhuan Li, Jie He, Yuelan Tao et al. · 2022 · Cells
50. A guide to ferroptosis in cancer
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51. Mechanisms and Molecular Targets of Artemisinin in Cancer Treatment
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52. Targeting fatty acid uptake and metabolism in cancer cells: A promising strategy for cancer treatment
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53. A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis
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54. Artemisinin-Type Drugs in Tumor Cell Death: Mechanisms, Combination Treatment with Biologics and Nanoparticle Delivery
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55. Unveiling ferroptosis as a promising therapeutic avenue for colorectal cancer and colitis treatment
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56. Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas
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57. Artesunate exerts protective effects against ulcerative colitis via suppressing Toll‑like receptor 4 and its downstream nuclear factor‑κB signaling pathways
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58. The Emerging Roles of Ferroptosis in Pathophysiology and Treatment of Acute Lung Injury
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59. Artesunate in glioblastoma therapy: Case reports and review of clinical studies
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60. Recent progress in nanotechnology based ferroptotic therapies for clinical applications
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61. The role of ferroptosis in esophageal cancer
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62. Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy
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63. Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway
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64. Ferroptosis regulation by methylation in cancer
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65. Heat stress induces ferroptosis of porcine Sertoli cells by enhancing CYP2C9-Ras- JNK axis
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66. Ferroptosis mechanisms and its novel potential therapeutic targets for DLBCL
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67. Antitumor effects of Andrographis via ferroptosis‑associated genes in gastric cancer
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71. The Art of War: Ferroptosis and Pancreatic Cancer
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72. Molecular Mechanisms of Ferroptosis and Its Role in Viral Pathogenesis
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73. The role of ferroptosis in digestive system cancer (Review)
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75. Advances in ferroptosis for castration-resistant prostate cancer treatment: novel drug targets and combination therapy strategies
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77. Artesunate Affects T Antigen Expression and Survival of Virus-Positive Merkel Cell Carcinoma
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78. Ferroptosis-related NFE2L2 and NOX4 Genes are Potential Risk Prognostic Biomarkers and Correlated with Immunogenic Features in Glioma
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80. Elaborate cooperation of poly(rC)-binding proteins 1/2 and glutathione in ferroptosis induced by plasma-activated Ringer's lactate
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82. Small molecule probes for cellular death machines
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83. Cashing in on ferroptosis against tumor cells: Usher in the next chapter
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86. Amentoflavone promotes ferroptosis by regulating reactive oxygen species (ROS) /5’AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) to inhibit the malignant progression of endometrial carcinoma cells
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87. Ferroptosis: Opportunities and Challenges in Treating Endometrial Cancer
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88. Artesunate, a new antimalarial clinical drug, exhibits potent anti‐AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
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89. Expression and Prognostic Significance of Ferroptosis-related Proteins SLC7A11 and GPX4 in Renal Cell Carcinoma
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90. Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate
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99. Ferroptosis‐Related Long Noncoding RNAs Have Excellent Predictive Ability for Multiomic Characteristics of Bladder Cancer
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100. Induction of ferroptosis by artesunate nanoparticles is an effective therapeutic strategy for hepatocellular carcinoma
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