Cited by 532Meta-analysis and systematic reviewsStatistical Methods in Clinical TrialsData Analysis with R

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netmeta : An R Package for Network Meta-Analysis Using Frequentist Methods

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Balduzzi, Sara, Rücker, Gerta, Nikolakopoulou, Adriani, Papakonstantinou, Theodoros, Salanti, Georgia, Efthimiou, Orestis, Schwarzer, Guido·2023·Journal of Statistical Software

DOI 10.18637/jss.v106.i02

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Abstract

Network meta-analysis compares different interventions for the same condition, by combining direct and indirect evidence derived from all eligible studies. Network metaanalysis has been increasingly used by applied scientists and it is a major research topic for methodologists. This article describes the R package netmeta, which adopts frequentist methods to fit network meta-analysis models. We provide a roadmap to perform network meta-analysis, along with an overview of the main functions of the package. We present three worked examples considering different types of outcomes and different data formats to facilitate researchers aiming to conduct network meta-analysis with netmeta.

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Authors: Balduzzi, S., Rücker, G., Nikolakopoulou, A., Papakonstantinou, T., Salanti, G., Efthimiou, O., & Schwarzer, G.
Affiliations: University of Freiburg (DE)
University of Bern (CH)
ORCID: Balduzzi, Sara
Rücker, Gerta
Nikolakopoulou, Adriani
Salanti, Georgia
Efthimiou, Orestis
Schwarzer, Guido
Venue: Journal of Statistical Software
Publisher: Foundation for Open Access Statistic
Published: 2023
Volume: 106
Issue: 2
ISSN: 1548-7660 (ISSN-L)
DOI: 10.18637/jss.v106.i02
OpenAlex: W4327640222
Cited by: 532
References: 67
Citations by year: 2026: 221 · 2025: 176 · 2024: 108 · 2023: 27
FWCI: 98.70
Type: journal article
Language: en
Open access: diamond
doi.org
Licence: cc-by
Locations: Journal of Statistical Software (publishedVersion, cc-by)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: National Science Foundation
Deutsche Forschungsgemeinschaft
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (186723, 179158, 180083)
Topics: Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
Physical Sciences › Mathematics › Statistics and Probability › Data Analysis with R
Keywords: network meta-analysis, frequentist methods, direct and indirect evidence, intervention comparison, statistical software

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netmeta : An R Package for Network Meta-Analysis Using Frequentist Methods

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