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Agent Laboratory: Using LLM Agents as Research Assistants

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Schmidgall, Samuel, Su, Yusheng, Wang, Ze, Sun, Ximeng, Wu, Jialian, Yu, Xiaodong, Liu, Jiang, Moor, Michael, Liu, Zicheng, Barsoum, Emad·2025·Findings of the Association for Computational Linguistics: EMNLP 2025

Abstract

Samuel Schmidgall, Yusheng Su, Ze Wang, Ximeng Sun, Jialian Wu, Xiaodong Yu, Jiang Liu, Michael Moor, Zicheng Liu, Emad Barsoum. Findings of the Association for Computational Linguistics: EMNLP 2025. 2025.

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Crossref · 10.18653/v1/2025.findings-emnlp.320

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  • Agent Laboratory's additional metrics include human and automated reviewer comparisons to ensure consistency and reliability in evaluations.

    “human and automated reviewer comparisons ensure consistency and reliability in evaluations.”

    From Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions (2025) · cites this paper as Schmidgall et al. (2025)

    In “Automated versus Human Reviews” (page not provided), the paper compares human and automated scores but finds substantial discrepancies, not consistency. It says automated reviews do not align closely with human reviews and recommends reporting human evaluations alongside automated scores to better understand paper quality. (LLM, conf=0.88)

    Checked by a reasoning model — may be wrong.

    Experimental — accuracy not yet measured
  • Agent Laboratory's performance dropped significantly in the literature review phase.

    “However, its performance dropped significantly in the literature review phase, reflecting the inherent challenges of automating structured literature reviews.”

    From Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions (2025) · cites this paper as Schmidgall et al., 2025

    Section 6.2 (page unavailable) reports that models struggled during the literature review phase and sometimes reached the maximum number of steps, terminating the phase. That supports a performance problem, but the paper does not establish a significant drop in performance or attribute it to an inherent difficulty of automating structured literature reviews. (LLM, conf=0.82)

    Experimental — accuracy not yet measured
  • Agent Laboratory introduces additional evaluation metrics for agentic AI systems.

    “The recent proposed framework, Agent Laboratory Schmidgall et al. (2025), introduces additional evaluation metrics that provide a more comprehensive assessment of agentic AI systems.”

    From Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions (2025) · cites this paper as Schmidgall et al. (2025)

    Sections 4.1 and 4.2 describe multiple measures used to evaluate Agent Laboratory, including research quality, usefulness, and co-pilot usability. The paper does not present these as newly introduced metrics for assessing agentic AI systems generally, or establish that they provide a more comprehensive assessment of such systems. Page numbers are unavailable in our copy. (LLM, conf=0.85)

    Experimental — accuracy not yet measured
  • Schmidgall et al. (2025) reported that among the phases of data preparation, experimentation, report writing, and research report generation, the literature review phase exhibited the highest failure rate.

    “For instance, Schmidgall et al. (2025) reported that among the phases of data preparation, experimentation, report writing, and research report generation, the literature review phase exhibited the highest failure rate.”

    From Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions (2025) · cites this paper as Schmidgall et al. (2025)

    Section 6.2 (Common failure modes; page unavailable) reports that models sometimes reached the step limit and terminated during literature review. The Figure 6 caption says phase-level success rates were evaluated, but the passages in our copy do not establish that literature review had the highest failure rate compared with data preparation, experimentation, or report writing. (LLM, conf=0.78)

    Experimental — accuracy not yet measured
  • Our analysis shows that while previous systems have performed well in fields such as chemistry, biology, and general science, literature review remains a significant challenge across nearly all approaches, especially in tasks like research idea generation and scientific discovery.

    “Our analysis shows that while previous systems have performed well in fields such as chemistry, biology, and general science, literature review remains a significant challenge across nearly all approaches, especially in tasks like research idea generation(Baek et al., 2024) and scientific discovery (Schmidgall et al., 2025).”

    From Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions (2025) · cites this paper as Schmidgall et al., 2025

    Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.

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Metadata

Authors
Schmidgall, S., Su, Y., Wang, Z., Sun, X., Wu, J., Yu, X., Liu, J., Moor, M., Liu, Z., & Barsoum, E.
Affiliations
  • Johns Hopkins University (US)
  • ETH Zurich (CH)
Venue
Findings of the Association for Computational Linguistics: EMNLP 2025
Published
2025
Pages
5977-6043
OpenAlex
W4416035220
Cited by
59
References
0
Citations by year
2026: 40 · 2025: 19
FWCI
56.25
Type
conference paper
Language
en
Open access
Licence
cc-by
Locations
Findings of the Association for Computational Linguistics: EMNLP (Findings of EMNLP) (publishedVersion, cc-by)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
  • Physical Sciences › Computer Science › Artificial Intelligence › Natural Language Processing Techniques
  • Social Sciences › General Social Sciences › Computational and Text Analysis Methods
Keywords
LLM agents, research assistants

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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