The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Occurrence of pharmaceuticals and personal care products in fish: Results of a national pilot study in the united states
Abstract
Pharmaceuticals and personal care products are being increasingly reported in a variety of biological matrices, including fish tissue; however, screening studies have presently not encompassed broad geographical areas. A national pilot study was initiated in the United States to assess the accumulation of pharmaceuticals and personal care products in fish sampled from five effluent-dominated rivers that receive direct discharge from wastewater treatment facilities in Chicago, Illinois; Dallas, Texas; Orlando, Florida; Phoenix, Arizona; and West Chester, Pennsylvania, USA. Fish were also collected from the Gila River, New Mexico, USA, as a reference condition expected to be minimally impacted by anthropogenic influence. High performance liquid chromatography-tandem mass spectrometry analysis of pharmaceuticals revealed the presence of norfluoxetine, sertraline, diphenhydramine, diltiazem, and carbamazepine at nanogram-per-gram concentrations in fillet composites from effluent-dominated sampling locations; the additional presence of fluoxetine and gemfibrozil was confirmed in liver tissue. Sertraline was detected at concentrations as high as 19 and 545 ng/g in fillet and liver tissue, respectively. Gas chromatography-tandem mass spectrometry analysis of personal care products in fillet composites revealed the presence of galaxolide and tonalide at maximum concentrations of 2,100 and 290 ng/g, respectively, and trace levels of triclosan. In general, more pharmaceuticals were detected at higher concentrations and with greater frequency in liver than in fillet tissues. Higher lipid content in liver tissue could not account for this discrepancy as no significant positive correlations were found between accumulated pharmaceutical concentrations and lipid content for either tissue type from any sampling site. In contrast, accumulation of the personal care products galaxolide and tonalide was significantly related to lipid content. Results suggest that the detection of pharmaceuticals and personal care products was dependent on the degree of wastewater treatment employed.
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Cites
Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es011055j · Cited by 7,953
Heberer, T. (2002) · Toxicology Letters · doi:10.1016/s0378-4274(02)00041-3 · Cited by 2,995
Occurrence of some organic UV filters in wastewater, in surface waters, and in fish from Swiss lakes
Balmer, M. E., Buser, H.-R., Müller, M. D., & Poiger, T. (2005) · Environmental Science & Technology · doi:10.1021/es040055r · Cited by 779 · cited 1×
“have been quantified in fish tissue matrices [10–17].”
Cited by
Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment
Ebele, A. J., Abou-Elwafa Abdallah, M., & Harrad, S. (2017) · Emerging Contaminants · doi:10.1016/j.emcon.2016.12.004 · Cited by 2,023
Wellington, E. M., Boxall, A. B., Cross, P., Feil, E. J., Gaze, W. H., Hawkey, P. M., Johnson-Rollings, A. S., Jones, D. L., Lee, N. M., Otten, W., et al. (2013) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(12)70317-1 · Cited by 1,122
Triclosan: environmental exposure, toxicity and mechanisms of action
Dann, A. B., & Hontela, A. (2011) · Journal of Applied Toxicology · doi:10.1002/jat.1660 · Cited by 868
Schultz, M. M., Furlong, E. T., Kolpin, D. W., Werner, S. L., Schoenfuss, H. L., Barber, L. B., Blazer, V. S., Norris, D. O., & Vajda, A. M. (2010) · Environmental Science & Technology · doi:10.1021/es9022706 · Cited by 537
Xiong, W., Zeng, G., Yang, Z., Zhou, Y., Zhang, C., Cheng, M., Liu, Y., Hu, L., Wan, J., Zhou, C., et al. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.01.249 · Cited by 532
Metadata
- Authors
- Ramirez, A. J., Brain, R. A., Usenko, S., Mottaleb, M. A., O'Donnell, J. G., Stahl, L. L., Wathen, J. B., Snyder, B. D., Pitt, J. L., Perez-Hurtado, P., Dobbins, L. L., Brooks, B. W., & Chambliss, C. K.
- Venue
- Environmental Toxicology and Chemistry
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-12-01
- Volume
- 28
- Issue
- 12
- Pages
- 2587-2597
- ISSN
- 0730-7268 (ISSN-L)
- 1552-8618
- OpenAlex
- W2085215470
- Cited by
- 486
- References
- 3
- FWCI
- 22.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ramirez, A. J., Brain, R. A., Usenko, S., Mottaleb, M. A., O'Donnell, J. G., Stahl, L. L., Wathen, J. B., Snyder, B. D., Pitt, J. L., Perez-Hurtado, P., Dobbins, L. L., Brooks, B. W., & Chambliss, C. K. (2009). Occurrence of pharmaceuticals and personal care products in fish: Results of a national pilot study in the united states. Environmental Toxicology and Chemistry. https://doi.org/10.1897/08-561.1
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
