Cited by 33Retinal Diseases and TreatmentsRetinal and Optic ConditionsDiabetes Management and Research

Doença Ocular Diabética

Open access
Henriques, José, Vaz-Pereira, Sara, Nascimento, João, Rosa, Paulo Caldeira·2015·Acta Médica Portuguesa

Abstract

A diabetes mellitus é uma doença metabólica crónica caracterizada por uma hiperglicémia mantida, o que leva a complicações macro e microvasculares. O olho é um dos principais órgãos atingidos nesta patologia e a retinopatia diabética a mais conhecida complicação microvascular e a principal causa de cegueira em indivíduos em idade activa. Todavia, a doença ocular diabética não se caracteriza apenas pela retinopatia diabética. Outras manifestações oculares importantes da diabetes mellitus são a catarata, o glaucoma, aneuropatia óptica isquémica, as parésias óculo-motoras e as erosões queráticas. Neste artigo de revisão destacamos a retinopatia diabética como a mais importante e característica complicação da diabetes mellitus, mas também as complicações menos conhecidas, com o objectivo de alertar e sensibilizar médicos não-oftalmologistas que lidam com indivíduos diabéticos, de modo a promover o diagnóstico e tratamento atempados destas alterações visualmente debilitantes.Palavras-chave: Complicações da Diabetes; Diabetes Mellitus; Retinopatia Diabética.

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  • There are many diabetes-related ocular diseases, such as cataract, glaucoma, ischemic optic neuropathy, cranial nerve palsies, and recurrent corneal erosion syndrome.

    “There are many diabetes-related ocular diseases, such as cataract, glaucoma, ischemic optic neuropathy, cranial nerve palsies, and recurrent corneal erosion syndrome (102).”

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Cites

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Research works printed but not linked: 12

  1. Klein R. Hyperglycemia and microvascular and macrovascular disease in diabetes. Diabetes Care. 1995;18:258-68.
  2. Henriques J, et al. Doença ocular diabética, Acta Med Port 2015 Jan-Feb;28(1):107-113 Observatório Nacional da Diabetes 11/2013. Lisboa: OND; 2013.
  3. Nabais C, Pereira J, Pereira P, Capote R, Morbeck S, Raposo J. Retinopatia diabética e condições associadas, que relação? Um estudo em doentes com diabetes mellitus tipo 2. Acta Med Port. 2011;24:71-8.
  4. Marinho Falcão I, Pinto C, Santos J, Fernandes MF, Ramalho L, Paixão E, et al. Estudo da prevalência da diabetes e das suas complicações numa coorte de diabéticos portugueses: um estudo na Rede Médicos - Sentinela. Rev Port Clin Geral. 2008;24:679-92.
  5. Antonetti DA, Klein R, Gardner TW. Diabetic retinopathy. N Engl J Med. 2012;366:1227-39.
  6. Goldin A, Beckam JA, Schmidt AM, Creager MA. Advanced glycation en products: sparking the development of diabetic vascular injury. Circulation. 2006;114:597-605.
  7. Schmidt AM, Yan SD, Wautier JL, Stern D. Activation of receptor for advanced glycation end products a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res. 1999;84:489-97.
  8. Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology. 1991;98:766-85.
  9. Mitchell P, Bandello F, Schmidt-Erfuth U, Lang GE, Masin P, Schlingeman RO, et al. The RESTORE study: ranibzumab mono therapy or combined with laser versus laser mono therapy for diabetic macular edma. Ophtalmology. 2011;118:615-25.
  10. Henriques J, Nascimento J, Rosa PC, Vaz FT, Amaro M. Laser fototérmico e sua interacção com a retina humana. Oftalmologia. 2012;36:353-64.
  11. Shen X, Zhong Y, Xie B, Cheng Y, Jiao Q. Pigment epithelium derived factor as an anti-inflammatory factor against decrease of glutamine synthetase expression in retinal Müller cells under high glucose conditions. Graef Arch Clin Exp Ophthalmol. 2010;248:1127-36.
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Authors
Henriques, J., Vaz-Pereira, S., Nascimento, J., & Rosa, P. C.
Affiliations
  • Instituto de Oftalmologia Dr Gama Pinto (PT)
  • University of Lisbon (PT)
  • Hospital Beatriz Ângelo (PT)
Venue
Acta Médica Portuguesa
Published
2015-02-27
Volume
28
Issue
1
Pages
107-113
ISSN
  • 0870-399X (ISSN-L)
  • 1646-0758
OpenAlex
W1758311627
Cited by
33
References
40
Citations by year
2026: 2 · 2025: 3 · 2023: 7 · 2022: 6 · 2021: 6 · 2020: 4 · 2019: 1 · 2016: 4
FWCI
1.28
Type
journal article
Language
pt
Open access
Licence
cc-by-nc
Locations
  • Acta Médica Portuguesa (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
  • Health Sciences › Medicine › Ophthalmology › Retinal and Optic Conditions
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
diabetic retinopathy, diabetes mellitus, microvascular complications, diabetic cataract, diabetic glaucoma, ischemic optic neuropathy, cranial nerve palsy, recurrent corneal erosion syndrome, blindness, early diagnosis
MeSH terms
Diabetic Retinopathy, Eye Diseases, Humans, Diabetes Complications

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