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Structural Interventions to Reduce and Eliminate Health Disparities
Open accessAbstract
Health disparities research in the United States over the past 2 decades has yielded considerable progress and contributed to a developing evidence base for interventions that tackle disparities in health status and access to care. However, health disparity interventions have focused primarily on individual and interpersonal factors, which are often limited in their ability to yield sustained improvements. Health disparities emerge and persist through complex mechanisms that include socioeconomic, environmental, and system-level factors. To accelerate the reduction of health disparities and yield enduring health outcomes requires broader approaches that intervene upon these structural determinants. Although an increasing number of innovative programs and policies have been deployed to address structural determinants, few explicitly focused on their impact on minority health and health disparities. Rigorously evaluated, evidence-based structural interventions are needed to address multilevel structural determinants that systemically lead to and perpetuate social and health inequities. This article highlights examples of structural interventions that have yielded health benefits, discusses challenges and opportunities for accelerating improvements in minority health, and proposes recommendations to foster the development of structural interventions likely to advance health disparities research.
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“When abusers fight for and obtain custody, what they are often looking for is not more meaningful involvement with their children, but rather acknowledgement of their status and importance (Bancroft et al., 2002; Brown et al., 2019; Silverman et al., 2004; Slote et al., 2005).”
From Post‐separation abuse: A concept analysis (2023) · cites this paper as Brown et al., 2019
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“01 14 (12) 17 (9) 23 (20) 60 (31) 31 (27) 59 (30)”
InfluentialHIV and Mental Health Services in the US South: A Meso Analysis
Ali, S., Stanton, M., Keo, B. S., Stanley, M., & McCormick, K. A. (2022) · Community Mental Health Journal · doi:10.1007/s10597-021-00925-3 · Cited by 7
Brawner, B. M. (2023) · Nursing Outlook · doi:10.1016/j.outlook.2023.102060 · Cited by 7
Liu, P. Y., Spiker, S., Holguin, M., & Schickedanz, A. B. (2023) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2023.101451 · Cited by 7
Health indicators of the National Roma Integration Strategy in Spain in the years 2006 and 2014
Parra‐Casado, D. L., Porras, J. A., & Estévez, J. F. (2020) · European Journal of Public Health · doi:10.1093/eurpub/ckaa070 · Cited by 7
Lopez‐Littleton, V., & Sampson, C. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819008-1.00013-4 · Cited by 8
Avwioro, G. O., Egwunyenga, A. O., Adjekuko, C. O., Mgbere, O. O., Odibo, E. O., Iyiola, S., Enitan, S. S., & Essien, E. J. (2021) · International Journal of Women s Health · doi:10.2147/ijwh.s303565 · Cited by 7
Increasing Access to Diabetes Education in Rural Alabama Through Telehealth
Ladner, K. A., Berry, S. R., & Hardy, J. (2022) · AJN American Journal of Nursing · doi:10.1097/01.naj.0000874116.81000.33 · Cited by 8
Lu, C., Jin, S., Tang, X., Lu, C., Lu, C., & Pang, J. (2020) · Healthcare · doi:10.3390/healthcare8030231 · Cited by 7
“[28], and other scholars used health indices such as life expectancy, cancer mortality, obesity, and weight problems to measure differences in citizens’ health levels across different regions.”
BackgroundMorales, L., Yowell, L., Molina, T., Smith, C. E., Arizcuren, J., & McClain, A. C. (2023) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2023.07.024 · Cited by 8
“23 27 Promoting local community and stakeholder engagement is a crucial factor in identifying the needs of low-resource communities to create shared goals and to support meaningful, sustainable, and scalable interventions.”
BackgroundInfluentialRoadmap for Health Equity: Understanding the Importance of Community-Engaged Research
Boden-Albala, B. M. (2024) · Stroke · doi:10.1161/strokeaha.124.046958 · Cited by 7
Wagemakers, A., Elkhuizen, S., Bindels, A., Wachter, M., Niewold, D., Derkzen, M. L., & Thompson, K. (2025) · Evaluation and Program Planning · doi:10.1016/j.evalprogplan.2025.102695 · Cited by 9
Dawson‐McClure, S., Rhule, D. M., Hamer, K.-A., Calzada, E. J., Kolawole, B., Mondesir, M., Rosenblatt, K., & Brotman, L. M. (2021) · Research on Family-School Partnerships · doi:10.1007/978-3-030-74617-9_4 · Cited by 6
Felner, J. K., Stieber, A., McCune, N., Reed, E., & Calzo, J. P. (2023) · Critical Public Health · doi:10.1080/09581596.2023.2271137 · Cited by 6
“…discourses effectively silenced (or even challenged) the body of evidence supporting the importance of structural-level (as opposed to individual-level) (Agurs-Collins et al., 2019; Brown et al., 2019) community-informed public health interventions to address health inequities (Trickett, 2011).”
BackgroundSilva, A., Saiyed, N. S., Canty, E., & Benjamins, M. R. (2023) · BMC Public Health · doi:10.1186/s12889-023-17214-1 · Cited by 6
Interventions addressing systemic racism in the US: A scoping review
Matos, L. A., Jaynes, S., VanRiel, Y. M., Barrett, N. J., Ledbetter, L., Cadavero, A. A., Grant, E. A., Webb, M. A., & Gonzalez-Guarda, R. M. (2024) · Social Science & Medicine · doi:10.1016/j.socscimed.2024.117403 · Cited by 8
Doing (and undoing) privilege: evaluating how public policy drives health inequities
Schram, A., Carrad, A., Townsend, B., Harris, P. J., Baum, F. E., Rychetnik, L., Allender, S. E., Pescud, M., Frank, N., Arthur, M., et al. (2025) · Critical Public Health · doi:10.1080/09581596.2025.2474078 · Cited by 7
“…to address structural inequities – as opposed to interventions targeting ‘at risk’ or marginalised communities and individuals – is still in its infancy (Brown et al., 2019). this paper aims to advance conceptual and analytical thinking for the study of structural drivers of entrenched advantage…”
Raghuram, H., Rajguru, A. J., Pathiyil, M. M., Brahmbhatt, A., Bhan, A., Spagnolo, J., & Naslund, J. A. (2025) · International Journal of Mental Health Systems · doi:10.1186/s13033-025-00671-z · Cited by 11
“…local resources and changing awareness and knowledge about cultural perceptions and determinants of mental health in local populations in the course of implementing modifications should continually inform and enhance the refinement, customization, and execution of adapted interventions [64, 74–76].”
Public Health Reports: 2020 in Review
Kuzmichev, A., Onyejiuwa, N., Jones, P. L., & Dean, H. D. (2021) · Public Health Reports · doi:10.1177/00333549211011306 · Cited by 6
Self-citationJaramillo‐Cardoso, A., Daye, D., Narayan, A. K., Spalluto, L. B., Alvarez, C., Rosman, D. A., Brink, J. A., & Flores, E. J. (2021) · Clinical Imaging · doi:10.1016/j.clinimag.2021.07.003 · Cited by 6
Greeven, S. J., Solá, P. A. F., Kercher, V. M. M., Coble, C. J., Pope, K. J., Erinosho, T., Grube, A., Evanovich, J. M., Werner, N. E., & Kercher, K. A. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1243560 · Cited by 6
Boyd, T., Garcia‐Fischer, I., Silvernale, C. J., Anyane‐Yeboa, A., & Staller, K. D. (2024) · Neurogastroenterology & Motility · doi:10.1111/nmo.14742 · Cited by 6
“36 In addition to the potential for implicit bias based on race and/or ethnicity, stigma related to IBS as a disease may exist and negatively influence both patient care and outcomes.”
BackgroundThe Dynamic Nature of the Socioeconomic Determinants of Cardiovascular Health: A Narrative Review
Alter, D. A., Austin, P. C., & Rosenfeld, A. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.01.029 · Cited by 7
Sandesara, U. N., Carson, S. L., Dopp, A. R., Perez, L. G., Sadia, A., Wali, S., Park, N. J., Casillas, A., Kim, G., Morales, M. G., et al. (2023) · Ethnicity & Disease · doi:10.18865/ed.decipher.68 · Cited by 6
Self-citationUnmasking Systemic Racism and Unconscious Bias in Medical Workplaces: A Call to Servant Leadership
Mezu‐Ndubuisi, O. J. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.018845 · Cited by 6
van Meurs, T., de Koster, W., van der Waal, J., & Groeniger, J. O. (2022) · European Journal of Public Health · doi:10.1093/eurpub/ckae013 · Cited by 5
Yarahmadi, S., Soleimani, M., Gholami, M., Fakhr‐Movahedi, A., & Madani, S. M. S. (2024) · BMC Medical Ethics · doi:10.1186/s12910-024-01118-9 · Cited by 5
“Since health disparities are a systemic and multi-level issue, evidence-based actions are needed to reduce them [28].”
BackgroundWolff, B., Nielsen, S., & Kiwanuka, A. (2024) · Frontiers in Digital Health · doi:10.3389/fdgth.2024.1490156 · Cited by 5
Neighborhood Factors Related to Cancer Screening in Texas: A Spatioecological Study
Rathod, R. A., Beauchamp, A., Shahan, K. L., Lin, K., Henry, K., Shariff‐Marco, S., Pruitt, S. L., & Hughes, A. E. (2024) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2024.12.012 · Cited by 5
Structural racism and racial disparities in stroke mortality in the United States, 2021
Gompers, A. D., Lewis, T. T., & Kramer, M. R. (2025) · Social Science & Medicine · doi:10.1016/j.socscimed.2025.117705 · Cited by 5
Metadata
- Authors
- Brown, A. F., Ma, G. X., Miranda, J., Eng, E., Castille, D., Brockie, T., Jones, P., Airhihenbuwa, C. O., Farhat, T., Zhu, L., & Trinh-Shevrin, C.
- Affiliations
- Fox Chase Cancer Center (US)
- Arleen F. Brown is with General Internal Medicine and Health Services Research, University of California Los Angeles (UCLA) and Olive View-UCLA Medical Center, Los Angeles, CA. Grace X. Ma is with Center for Asian Health, Fox Chase Cancer Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA. Jeanne Miranda is with the Department of Psychiatry and Biobehavioral Sciences, Jonathan and Karin Fielding School of Public Health, UCLA. Eugenia Eng is with the Gillings School of Global...
- Venue
- American Journal of Public Health
- Publisher
- American Public Health Association
- Published
- 2019-01
- Volume
- 109
- Issue
- S1
- Pages
- S72-S78
- ISSN
- 0090-0036 (ISSN-L)
- 1541-0048
- PMC
- PMC6356131
- OpenAlex
- W2912527863
- Cited by
- 465
- References
- 45
- Citations by year
- 2026: 52 · 2025: 97 · 2024: 86 · 2023: 79 · 2022: 58 · 2021: 53 · 2020: 30 · 2019: 9
- FWCI
- 36.42
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Public Health (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- TUScholarShare (Temple University) (submittedVersion)
- Funders
- National Institutes of Health (UL1TR001881)
- National Cancer Institute (U54CA153513)
- National Institute of Neurological Disorders and Stroke (U54NS081764)
- National Center for Chronic Disease Prevention and Health Promotion (U58 DP005828, U48DP005008)
- National Center for Advancing Translational Sciences
- National Institute on Minority Health and Health Disparities (U54MD000538)
- Topics
- Social Sciences › Health › Health disparities and outcomes
- Social Sciences › Health › Public Health and Social Inequalities
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Public Health Policies and Education
- Keywords
- health disparities, structural interventions, structural determinants of health, minority health, health care access, socioeconomic factors, environmental factors, health policy, multilevel interventions, evidence-based interventions
- MeSH terms
- Health Status, Humans, Minority Groups, Socioeconomic Factors, United States, Healthcare Disparities
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