The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Outcome Assessment in Clinical Trials of Fracture-Healing
Abstract
Although there are numerous methods for defining fracture-healing in clinical studies, no consensus exists regarding the most valid and reliable manner for assessing union or for determining which outcomes are most important. This article summarizes and describes methods for the clinical assessment of fracture-healing and reports results from a systematic review of prevalent definitions currently used in published clinical studies. Conventional radiography and ad hoc clinical definitions continue to be the most commonly used means of assessing fracture-healing in clinical studies. Investigators must improve upon and apply more rigorous outcome assessment in clinical trials, emphasize patient-important outcomes, and report factors that may bias estimated effects.
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Citations
Cites
The reliability of plain radiography in experimental fracture healing
Blokhuis, T. J., de Bruine, J. H. D., Bramer, J. A. M., den Boer, F. C., Bakker, F. C., Patka, P., Haarman, H. J. T. M., & Manoliu, R. A. (2001) · Skeletal Radiology · doi:10.1007/s002560000317 · Cited by 113
Cited by
Regenerative Effects of Transplanted Mesenchymal Stem Cells in Fracture Healing
Granero-Moltó, F., Weis, J. A., Miga, M. I., Landis, B., Myers, T. J., O'Rear, L., Longobardi, L., Jansen, E. D., Mortlock, D. P., & Spagnoli, A. (2009) · Stem Cells · doi:10.1002/stem.103 · Cited by 530
Continuous implant load monitoring to assess bone healing status-evidence from animal testing
Windolf, M., Varjas, V., Gehweiler, D., Schwyn, R., Arens, D., Constant, C., Zeiter, S., Richards, R. G., & Ernst, M. (2022) · Medicina · doi:10.3390/medicina58070858 · Cited by 63
Effect of Bone Morphogenetic Protein-2 in the Treatment of Long Bone Non-Unions
Fuchs, T., Stolberg-Stolberg, J., Michel, P. A., Garcia, P., Amler, S., Wähnert, D., & Raschke, M. J. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10194597 · Cited by 36
Metadata
- Authors
- Morshed, S., Corrales, L., Genant, H., & Miclau, T.
- Venue
- Journal of Bone and Joint Surgery
- Published
- 2008-02
- Volume
- 90
- Issue
- Supplement_1
- Pages
- 62-67
- ISSN
- 0021-9355 (ISSN-L)
- 1535-1386
- OpenAlex
- W2133706509
- Cited by
- 170
- References
- 1
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Morshed, S., Corrales, L., Genant, H., & Miclau, T. (2008). Outcome Assessment in Clinical Trials of Fracture-Healing. Journal of Bone and Joint Surgery. https://doi.org/10.2106/jbjs.g.01556
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.