The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The Influence of Obesity on the Complication Rate and Outcome of Total Knee Arthroplasty: A Meta-Analysis and Systematic Literature Review
Open accessAbstract
BACKGROUND: The increase in the number of individuals with an unhealthy high body weight is particularly relevant in the United States. Obesity (body mass index ≥ 30 kg/m2) is a well-documented risk factor for the development of osteoarthritis. Furthermore, an increased prevalence of total knee arthroplasty in obese individuals has been observed in the last decades. The primary aim of this systematic literature review was to determine whether obesity has a negative influence on outcome after primary total knee arthroplasty. METHODS: A search of the literature was performed, and studies comparing the outcome of total knee arthroplasty in different weight groups were included. The methodology of the included studies was scored according to the Cochrane guidelines. Data extraction and pooling were performed. The weighted mean difference for continuous data and the weighted odds ratio for dichotomous variables were calculated. Heterogeneity was calculated with use of the I2 statistic. RESULTS: After consensus was reached, twenty studies were included in the data analysis. The presence of any infection was reported in fourteen studies including 15,276 patients (I2, 26%). Overall, infection occurred more often in obese patients, with an odds ratio of 1.90 (95% confidence interval [CI], 1.46 to 2.47). Deep infection requiring surgical debridement was reported in nine studies including 5061 patients (I2, 0%). Deep infection occurred more often in obese patients, with an odds ratio of 2.38 (95% CI, 1.28 to 4.55). Revision of the total knee arthroplasty, defined as exchange or removal of the components for any reason, was documented in eleven studies including 12,101 patients (I2, 25%). Revision for any reason occurred more often in obese patients, with an odds ratio of 1.30 (95% CI, 1.02 to 1.67). CONCLUSIONS: Obesity had a negative influence on outcome after total knee arthroplasty.
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Cites
Measuring inconsistency in meta-analyses
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Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
A Potential Decline in Life Expectancy in the United States in the 21st Century
Olshansky, S. J., Passaro, D. J., Hershow, R. C., Layden, J., Carnes, B. A., Brody, J., Hayflick, L., Butler, R. N., Allison, D. B., & Ludwig, D. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmsr043743 · Cited by 2,612
Updated Method Guidelines for Systematic Reviews in the Cochrane Collaboration Back Review Group
van Tulder, M., Furlan, A., Bombardier, C., & Bouter, L. (2003) · Spine · doi:10.1097/01.brs.0000065484.95996.af · Cited by 2,180
Cited by
Belmont, P. J., Goodman, G. P., Waterman, B. R., Bader, J. O., & Schoenfeld, A. J. (2014) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.m.00018 · Cited by 438
De Luca, M., Angrisani, L., Himpens, J., Busetto, L., Scopinaro, N., Weiner, R., Sartori, A., Stier, C., Lakdawala, M., Bhasker, A. G., et al. (2016) · Obesity Surgery · doi:10.1007/s11695-016-2271-4 · Cited by 296
Werner, B. C., Kurkis, G. M., Gwathmey, F. W., & Browne, J. A. (2015) · The Journal of Arthroplasty · doi:10.1016/j.arth.2014.11.039 · Cited by 101
McLawhorn, A. S., Levack, A. E., Lee, Y.-Y., Ge, Y., Do, H., & Dodwell, E. R. (2018) · The Journal of Arthroplasty · doi:10.1016/j.arth.2017.11.056 · Cited by 93
Pavlovic, N., Boland, R. A., Brady, B., Genel, F., Harris, I. A., Flood, V. M., & Naylor, J. M. (2021) · Clinical Obesity · doi:10.1111/cob.12485 · Cited by 22
Metadata
- Authors
- Kerkhoffs, G. M. M. J., Servien, E., Dunn, W., Dahm, D., Bramer, J. A. M., & Haverkamp, D.
- Venue
- The Journal of Bone & Joint Surgery
- Published
- 2012-10
- Volume
- 94
- Issue
- 20
- Pages
- 1839-1844
- ISSN
- 0021-9355 (ISSN-L)
- OpenAlex
- W2047369426
- Cited by
- 503
- References
- 4
- FWCI
- 29.16
- Type
- journal article
- Language
- en
- Open access
- green
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- Kerkhoffs, G. M. M. J., Servien, E., Dunn, W., Dahm, D., Bramer, J. A. M., & Haverkamp, D. (2012). The Influence of Obesity on the Complication Rate and Outcome of Total Knee Arthroplasty: A Meta-Analysis and Systematic Literature Review. The Journal of Bone & Joint Surgery. https://doi.org/10.2106/jbjs.k.00820
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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